Article
Biology
Anna Svensson, Jatesada Jiwakanon, Caroline Fossum, Anne-Marie Dalin
Summary: The study found that IL-23 plays a role in the inflammatory response after insemination in gilts, with the mRNA expression of IL-23 detected in the endometrium regardless of the insemination treatment.
BMC RESEARCH NOTES
(2021)
Review
Medicine, General & Internal
Michal Jeseta, Anna Pospisilova, Lenka Mekinova, Katerina Franzova, Pavel Ventruba, Eva Lousova, Bartosz Kempisty, Tomas Ozdian, Jana Zakova, Igor Crha
Summary: The compounds in seminal plasma have potential as biomarkers for male fertility and can be used for diagnosing different types of azoospermia. Distinguishing between obstructive and non-obstructive azoospermia is important for effective treatment. Proteins in seminal plasma, particularly testicular and epididymal proteins, can serve as biomarkers for diagnosing azoospermia. Combining multiple biomarkers, such as TEX101 and ECM1 or TEX101 and SPAG1, can improve diagnostic accuracy.
Article
Biology
Pol Fernandez-Lopez, Joan Garriga, Isabel Casas, Marc Yeste, Frederic Bartumeus
Summary: Understanding the relationship between sperm motility and fertility is important for both evolutionary and practical purposes. This study characterizes pig sperm motility using t-SNE, a method that reveals a hierarchical organization of sperm motility across individuals and enables accurate fertility predictions. The findings suggest that high-speed and straight-lined motion are positively correlated with fertility and are more important than other sources of variability. The study proposes the use of embedding methods and Bayesian inference frameworks to better understand the relationship between fertility and sperm motility in animals, including humans.
COMMUNICATIONS BIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Inmaculada Parrilla, Heriberto Rodriguez-Martinez, Cristina Cuello, Maria Antonia Gil, Emilio A. Martinez
Summary: This study evaluated the effect of infused frozen-thawed seminal plasma (SP) and TGF-beta 1 on fertility and prolificacy in sows post-cervically inseminated. The results showed that pre-infusions of SP or TGF-beta 1 did not influence subsequent fertility and prolificacy in the sows.
REPRODUCTION IN DOMESTIC ANIMALS
(2022)
Article
Veterinary Sciences
Bingbing Xu, Xue Bai, Jian Zhang, Boyuan Li, Yanjun Zhang, Rui Su, Ruijun Wang, Zhiying Wang, Qi Lv, Jiaxin Zhang, Jinquan Li
Summary: This study investigated the factors affecting sperm freezability in goat seminal plasma. Goats were divided into high-freezability (HF) and low-freezability (LF) groups based on the total motility of thawed sperm. The seminal plasma composition was found to be related to the differences in sperm motility and integrity. Metabolomic analysis revealed clear separations in metabolic patterns between the HF and LF groups. Differential metabolites, including L-glutamine, L-aspartate, L-arginine, phenylpyruvate, benzoic acid, ketoisocaproic acid, and choline, were identified as potential biomarkers for sperm freezability. These metabolites may directly affect sperm freezability or regulate anabolic processes in sperm.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Heriberto Rodriguez-Martinez, Emilio A. Martinez, Juan J. Calvete, Fernando J. Pena Vega, Jordi Roca
Summary: Seminal plasma, a non-cellular component of semen, plays a crucial role in sperm function and interactions with the female reproductive tract. It participates in diverse pre-fertilization events and triggers gene function changes to prepare for successful pregnancy. Despite the fertility of SP-free spermatozoa, its components have diagnostic biomarker potential and can be used as additives to improve reproductive strategies in livestock and humans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Masood Abu-Halima, Lea Simone Becker, Mohammad A. Al Smadi, Lea Sophie Kunz, Laura Groeger, Eckart Meese
Summary: This study investigated the role of miRNAs and SPAG7 in male infertility. It found that miR-424 and miR-497 were upregulated in oligoasthenozoospermic men, while SPAG7 expression was downregulated. These findings suggest a potential regulatory role of miR-424 and SPAG7 in the pathogenesis of oligoasthenozoospermia.
SCIENTIFIC REPORTS
(2023)
Article
Reproductive Biology
Ana Carolina Pedrosa, Mariana Andrade Torres, Diego Vilela Alkmin, Jorge E. P. Pinzon, Simone Maria Massami Kitamura Martins, Juliano Coelho da Silveira, Andre Furugen Cesar de Andrade
Summary: Research has shown that ssc-miR-503, ssc-miR-130a, and ssc-miR-9 are related to low sperm cryotolerance in boar semen and can be used as biomarkers to predict their low ability to tolerate the cryopreservation process.
Article
Agriculture, Dairy & Animal Science
Yentel Mateo-Otero, Pol Fernandez-Lopez, Ariadna Delgado-Bermudez, Pau Nolis, Jordi Roca, Jordi Miro, Isabel Barranco, Marc Yeste
Summary: This study evaluated the relationship between seminal plasma metabolites and in vivo fertility outcomes in pigs. Using NMR spectroscopy, specific metabolites such as lactate, carnitine, and glucose were found to be potential biomarkers for predicting farrowing rate and litter size. These findings suggest that assessing selected SP-metabolites in ejaculates through NMR spectroscopy could serve as a promising non-invasive tool to predict in vivo fertility in pigs.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Filip Tirpak, Marko Halo, Marian Tomka, Tomag Slanina, Katarina Tokarova, Martyna Blaszczyk-Altman, Lucia Dianova, Peter Ivanic, Robert Kirchner, Agnieszka Gren, Norbert Lukac, Peter Massanyi
Summary: This study monitored the chemical and biochemical composition of bovine seminal plasma and correlated it with sperm quality parameters. The results showed that seminal Fe has beneficial effects on sperm motility, while Mg has beneficial effects on sperm velocity and viability. On the contrary, negative correlations were observed between Zn and sperm velocity, as well as between seminal cholesterol content and motility. These findings suggest that seminal plasma has the potential to serve as a potential biomarker for bull reproductive health.
Article
Agriculture, Dairy & Animal Science
Andres Suarez-Usbeck, Olga Mitjana, Maria Teresa Tejedor, Cristina Bonastre, Jorge Sistac, Antonio Ubiergo, Maria Victoria Falceto
Summary: The study found that the use of FTAI-PCAI protocol combined with buserelin in gilts can increase piglet birth weight, shorten estrus duration, and reduce delivery batch length in spring.
Article
Agriculture, Dairy & Animal Science
Fahimeh Seyedasgari, Behnam Asadi, Ellen Kim
Summary: This study investigated the effect of adding seminal plasma to frozen-thawed semen on the quality of sperm and pregnancy following insemination in dromedary camels. The results showed that adding seminal plasma can improve sperm longevity and motility after thawing, with significant between-bull variation in effect.
Article
Fisheries
Takafumi Fujimoto, Takahisa Kaneyasu, Mitsuru Endoh, Yuya Kogame, Joanna Nynca, Andrzej Ciereszko, Eisuke Takahashi, Etsuro Yamaha, Kiyoshi Naruse, Katsutoshi Arai
Summary: The aim of this study was to evaluate the cryopreservation of masu salmon semen using a specific extender and to investigate the relationship between semen parameters and post-thaw sperm motility. The results showed that the suitability of semen for cryopreservation was affected by the condition of the parental fish.
Article
Agriculture, Dairy & Animal Science
Lorena Padilla, Marina Lopez-Arjona, Silvia Martinez-Subiela, Heriberto Rodriguez-Martinez, Jordi Roca, Isabel Barranco
Summary: The study found that the concentration of OXT in seminal plasma varies between boars and ejaculates within boars but not between breeds. Ejaculates with higher OXT concentration tend to have larger volume and come from younger boars, while boars with positive farrowing rate deviation have higher OXT concentration.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Maria Gemma Millan de la Blanca, Eva Martinez-Nevado, Cristina Castano, Juncal Garcia, Berenice Bernal, Adolfo Toledano-Diaz, Milagros Cristina Esteso, Paula Boveda, Lucia Martinez-Fresneda, Antonio Lopez-Sebastian, Julian Santiago-Moreno
Summary: The American flamingo is a useful model for developing successful semen cryopreservation procedures, applicable to threatened related species from the family Phoenicopteridae, to allow genetic material banking. The study aimed to develop effective sperm cryopreservation protocols by examining the influences of two permeating cryoprotectants and seminal plasma removal. The findings showed that there were no differences between Me2SO and DMA for successful freezing of flamingo sperm, and seminal plasma removal did not benefit sperm cryopreservation.
Article
Veterinary Sciences
Karin M. Olofsson, Bernt Hjertner, Caroline Fossum, Charles M. Press, Ronny Lindberg
VETERINARY JOURNAL
(2015)
Article
Immunology
Bernt Hjertner, Theresa Bengtsson, Bror Morein, Staffan Paulie, Caroline Fossum
Article
Genetics & Heredity
Xingyu Ye, Mikael Berg, Caroline Fossum, Per Wallgren, Anne-Lie Blomstrom
Article
Biochemical Research Methods
Caroline Fossum, Bernt Hjertner, Tanja Lovgren, Lisbeth Fuxler, Wasin Charerntantanakul, Per Wallgren
JOURNAL OF VIROLOGICAL METHODS
(2014)
Article
Multidisciplinary Sciences
Anne-Lie Blomstrom, Caroline Fossum, Per Wallgren, Mikael Berg
Article
Immunology
Caroline Fossum, Bernt Hjertner, Viktor Ahlberg, Wasin Charerntantanakul, Kathy McIntosh, Lisbeth Fuxler, Navisraj Balagunaseelan, Per Wallgren, Karin Lovgren Bengtssone
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
(2014)
Article
Veterinary Sciences
Bernt Hjertner, Karin M. Olofsson, Ronny Lindberg, Lisbeth Fuxler, Caroline Fossum
VETERINARY JOURNAL
(2013)
Article
Virology
Anne-Lie Blomstrom, Xingyu Ye, Caroline Fossum, Per Wallgren, Mikael Berg
Article
Immunology
Stina Hellman, Eva Tyden, Bernt Hjertner, Frida Nilsfors, Kefei Hu, Bror Morein, Caroline Fossum
Summary: The study aimed to understand the impact of different larval stages of Strongylus vulgaris and cyathostomins on cytokine responses in equine peripheral blood mononuclear cells (eqPBMC). It was found that the L4 stage of S. vulgaris induces a distinct cytokine profile compared to the earlier L3 stage and cyathostomins, which may have implications for future vaccine design.
PARASITE IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Bernt Hjertner, Claudia Lutzelschwab, Elise Schieck, Benjamin Nzau, Sonal Henson, Marie Sjolund, Caroline Fossum, Ulf Magnusson
Summary: This study evaluated the potential of genes considered biomarkers in humans to differentially diagnose bacterial from viral infections in pigs. Utilizing these genes, infected pigs could be effectively distinguished from healthy pigs.
Article
Biology
Anna Svensson, Jatesada Jiwakanon, Caroline Fossum, Anne-Marie Dalin
Summary: The study found that IL-23 plays a role in the inflammatory response after insemination in gilts, with the mRNA expression of IL-23 detected in the endometrium regardless of the insemination treatment.
BMC RESEARCH NOTES
(2021)
Article
Veterinary Sciences
Hedvig Stenberg, Stina Hellman, Lisa Lindstrom, Magdalena Jacobson, Caroline Fossum, Juliette Hayer, Maja Malmberg
Summary: The results of this study provide evidence of an APPV-induced antiviral cytokine response, but found no lesions related to the infection or any support for a common causative agent.
BMC VETERINARY RESEARCH
(2022)
Article
Veterinary Sciences
Stina Hellman, Bernt Hjertner, Bror Morein, Caroline Fossum
VETERINARY RESEARCH
(2018)
Meeting Abstract
Immunology
Hellman Stina, Hjertner Bernt, Morein Bror, Fossum Caroline
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
(2017)
Article
Veterinary Sciences
Viktor Ahlberg, Bernt Hjertner, Per Wallgren, Stina Hellman, Karin Lovgren Bengtsson, Caroline Fossum
VETERINARY RESEARCH
(2017)