Article
Agriculture, Dairy & Animal Science
Sihua Jin, Jingjing Xia, Fumin Jia, Lijun Jiang, Xin Wang, Xuling Liu, Xing Liu, Zhaoyu Geng
Summary: Characterization of the complete mitochondrial genome of Pingpu Yellow chicken revealed high genetic diversity and potentially three maternal lineages, indicating the breed's close relation to Luhua and Nandan chickens.
Article
Agriculture, Dairy & Animal Science
Ahmed S. Al-Jumaili, Olivier Hanotte
Summary: Phylogeography is important in understanding the evolutionary interpretations of geographical distribution. In this study, the effectiveness of full mtDNA sequences and W chromosome polymorphisms for phylogeographic studies of village chickens was assessed. The results showed that full mtDNA sequences are more useful in tracing the maternal historical genome background compared to the W chromosome.
ANIMAL BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
David H. Mauki, Adeniyi C. Adeola, Said Ng'ang'a, Abdulfatai Tijjani, Ibikunle Mark Akanbi, Oscar J. Sanke, Abdussamad M. Abdussamad, Sunday C. Olaogun, Jebi Ibrahim, Philip M. Dawuda, Godwin F. Mangbon, Paul S. Gwakisa, Ting-Ting Yin, Min-Sheng Peng, Ya-Ping Zhang
Summary: This study analyzed the genetic diversity of cattle samples from Nigeria using both maternal and paternal DNA markers, revealing that Nigerian cattle are mainly clustered with African cattle and have a zebu haplogroup in terms of paternal analysis. There was no signal of maternal genetic structure in Nigerian cattle population, suggesting extensive genetic intermixing within the country.
Article
Genetics & Heredity
K. Haddish, E. Chierto, G. Di Vella, D. Lacerenza, S. Raddi, S. Aneli, A. L. Bogale, E. Kidane, A. Yizengaw, Y. Getaneh, G. Tewelemedhin, H. R. S. Kumar, C. Robino
Summary: The study investigated allele frequencies of autosomal STR markers and haplotype frequencies of Y- and X-STR markers in the Tigray population of Ethiopia. Results showed low random match probability and high Y-STR diversity in Tigray males. The findings can be utilized by local forensic genetics services and in genetic identification procedures for victims of human trafficking in the Mediterranean Sea.
FORENSIC SCIENCE INTERNATIONAL-GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Adrianna D. Musial, Katarzyna Ropka-Molik, Monika Stefaniuk-Szmukier, Grzegorz Mycka, Agnieszka Bieniek, Nataliya Yasynetska
Summary: Przewalski horses are the last population of wild horses, descended from herds domesticated by the Botai culture 5000 years ago. This study aimed to determine the maternal variation of Przewalski horses in Askania-Nova Reserve through analysis of mitochondrial DNA and Y chromosome markers, as well as coat color genes. The results showed distinct haplotypes in the mtDNA analysis, unique Y chromosome polymorphisms, and confirmation of native, wild genotypes through coat color analysis.
MOLECULAR BIOLOGY REPORTS
(2023)
Article
Multidisciplinary Sciences
Zefei Wang, Mengyuan Song, Qiang Lyu, Jun Ying, Qian Wu, Feng Song, Lanrui Jiang, Xiaowen Wei, Shuangshuang Wang, Fei Wang, Yuxiang Zhou, Xingbo Song, Haibo Luo
Summary: The Qiang ethnic group, one of the oldest in China, has been found to have extensive genetic connections with other ethnic groups, especially the Han, which supports their status as the oldest group in the Sino-Tibetan language family.
Article
Agriculture, Dairy & Animal Science
Fereshte Kaviani, Mohsen Gholizadeh, Hasan Hafezian
Summary: The objective of this study was to investigate the genetic inheritance of growth traits in Mazandaran native chickens by assessing autosomal and sex-linked genetic effects. It was found that there was no significant sex-linked additive genetic effect on body weight at hatching (BW0), while for body weight at 8 weeks (BW8) and 12 weeks (BW12), a model including autosomal, sex-linked direct additive, and maternal effects without global dosage compensation on the Z chromosome was the most appropriate. The heritability estimates for autosomal effects were relatively low, while the estimates for sex-linked effects were higher, particularly for BW12. There were positive genetic correlations among all traits, and a high genetic correlation between BW8 and BW12 due to sex-linked effects. Maternal genetic correlations were also observed between different body weight traits.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2023)
Article
Genetics & Heredity
Lirong Jiang, Jing Liu, Suyu Li, Yufeng Wen, Xinyue Zheng, Liu Qin, Yiping Hou, Zheng Wang
Summary: This study evaluated the performance of four commonly used variant callers in the heterogeneity authentication of human mtDNA and developed a python-based nanopore analytics pipeline, CmVCall. The results showed that CmVCall can accurately identify heterogeneity and reveal significant levels of individual differences. This analysis pipeline lays a solid foundation for comprehensive research on the characteristics of the mitochondrial genome.
FORENSIC SCIENCE INTERNATIONAL-GENETICS
(2023)
Article
Genetics & Heredity
Nuket Bilgen, Mervenur Guvendi, Efe Sezgin, Huseyin Can, Ahmet Efe Koseoglu, Sedef Erkunt Alak, Mert Doskaya, Cemal Un
Summary: This study investigated the mitochondrial DNA diversity in random bred cats from various regions across Turkey and compared it with the mitochondrial DNA profiles of Turkish Angora and Turkish Van breeds. The analysis identified nine 'universal' mitochondrial DNA profiles and one 'outlier' profile in random bred cats. The haplotype structure in random bred cats showed remarkable diversity compared to Turkish Angora and Van breeds. Overall, this study expands our understanding of the feline genetic landscape in Turkey and lays the foundation for future research on the evolutionary trajectories and genetic legacies of these feline populations.
Article
Evolutionary Biology
Irina Kulikova, Sergei Shedko, Yury N. Zhuravlev, Philip Lavretsky, Jeffrey L. Peters
Summary: Closely related bird species often show high genetic differentiation in the Z-chromosome, which may contribute to reproductive isolation through the presence of selection loci. A study on Mallard and Chinese Spot-billed Duck using ddRAD-seq revealed a 4.5 times greater differentiation on the Z-chromosome compared to autosomal DNA, including three fixed differences in SNPs.
Article
Medicine, Legal
Suhair M. Jabbar, Nihad A. M. Al-Rashedi
Summary: Although Iraq has a rich cultural history and unique geographic location, there is a lack of forensic reference data on mitochondrial DNA (mtDNA) control region in Iraqi populations, especially in the southern part of the country. This study conducted forensic analysis on 203 unrelated individuals in Samawah City, revealing 111 haplotypes with 143 polymorphic positions in the mtDNA control region. The data generated will be available for further research and forensic investigations.
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
(2021)
Article
Genetics & Heredity
Bo Ran, Wei Zhu, Xiaoling Zhao, Linxiang Li, Zhixin Yi, Miao Li, Tao Wang, Diyan Li
Summary: This study analyzed the genetic structure and evolutionary relationships of the Mountainous Meihua chicken. It found that the chicken has high genetic diversity and good breeding potential. It also showed a moderate degree of differentiation from other chicken breeds and no evidence of past population expansions. The study identified four unique maternal lineages in the Mountainous Meihua chicken.
Article
Anthropology
Wen-qing Yue, Mao-ling Sun, Feng Han, Jiu-jun Li, Tsewang Rigzin, Tashi Dhondup, Hai-bo Liu, Dong-yue Li, Xuan Li, Yan-ming Xu, Xiao-na Li
Summary: The study analyzed the mtDNA control region sequences of Tibetan individuals from the Naqu region of Tibet, and found a unique population structure in the Naqu Tibetan population through population comparison with other groups.
ANNALS OF HUMAN BIOLOGY
(2021)
Article
Medicine, Legal
Fu-Chi Yang, Bill Tseng, Chun-Yen Lin, Yu-Jen Yu, Adrian Linacre, James Chun- Lee
Summary: This study demonstrated the accuracy of population and subpopulation assignment using mitochondrial genome DNA sequences and the K-nearest neighbors algorithm. Results showed high accuracy in assigning individuals to continental populations and subpopulations, providing valuable insights for research and applications involving subpopulations.
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
(2021)
Article
Medicine, General & Internal
Rebeca Lorca, Andrea Aparicio, Juan Gomez, Rut Alvarez-Velasco, Isaac Pascual, Pablo Avanzas, Francisco Gonzalez-Urbistondo, Alberto Alen, Daniel Vazquez-Coto, Mar Gonzalez-Fernandez, Claudia Garcia-Lago, Elias Cuesta-Llavona, Cesar Moris, Eliecer Coto
Summary: Mitochondrial DNA (mtDNA) is different from nuclear genome in terms of inheritance patterns, susceptibility to mutations, and heteroplasmy. This study aimed to evaluate mtDNA variants associated with premature cardiovascular disease. Patients with premature myocardial infarction were compared with a control group, and the presence of mtDNA polymorphisms and clinical data were examined. The results showed that certain mtDNA mutations and heteroplasmy were significantly more frequent in premature myocardial infarction patients, particularly in males. These findings suggest that mtDNA mutations and heteroplasmy may be associated with unstable premature atherosclerosis disease in men, emphasizing the importance of protective mitochondrial pathways and preventing exposure to cardiovascular risk factors.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
Sumaya Kambal, Amina E. Abdelrahim, Olivier Hanotte, Ryo Nakao, Abeer M. Alkhaibari, Bashir Salim
Summary: The study found that there is high genetic polymorphism in maternal genetic diversity in the Western Baggara cattle breed, specifically in the Nyalawi and Daeinawi populations, with low genetic differentiation between populations. Approximate Bayesian computation showed a larger maternal effective population size in Nyalawi compared to Daeinawi, and both populations experienced population expansions before the arrival of zebu into the continent.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2022)
Article
Multidisciplinary Sciences
A. Talenti, J. Powell, J. D. Hemmink, E. A. J. Cook, D. Wragg, S. Jayaraman, E. Paxton, C. Ezeasor, E. T. Obishakin, E. R. Agusi, A. Tijjani, K. Marshall, A. Fisch, B. R. Ferreira, A. Qasim, U. Chaudhry, P. Wiener, P. Toye, L. J. Morrison, T. Connelley, J. G. D. Prendergast
Summary: This study generated assemblies for African cattle breeds and integrated them with genomic data for global cattle breeds into a graph genome. Compared to the current reference assembly, this more representative assembly contains additional sequence, increases read mapping rates, reduces biases, and improves structural variant calling consistency.
NATURE COMMUNICATIONS
(2022)
Article
Agriculture, Dairy & Animal Science
S. Tavaniello, A. Slawinska, F. Sirri, M. Wu, D. De Marzo, M. Siwek, G. Maiorano
Summary: This study evaluated the in vivo performance, carcass and meat quality traits of slow-growing chickens stimulated in ovo with trans galactooligosaccharides (GOS), and exposed to heat stress. The results showed that GOS had a significant impact on the performance of the chickens, but did not alleviate the negative effects of heat stress.
Correction
Multidisciplinary Sciences
A. Talenti, J. Powell, J. D. Hemmink, E. A. J. Cook, D. Wragg, S. Jayaraman, E. Paxton, C. Ezeasor, E. T. Obishakin, E. R. Agusi, A. Tijjani, W. Amanyire, D. Muhanguzi, K. Marshall, A. Fisch, B. R. Ferreira, A. Qasim, U. Chaudhry, P. Wiener, P. Toye, L. J. Morrison, T. Connelley, J. G. D. Prendergast
NATURE COMMUNICATIONS
(2022)
Article
Agriculture, Dairy & Animal Science
Michelle Paradowska, Aleksandra Dunislawska, Maria Siwek, Anna Slawinska
Summary: Antimicrobial resistance poses an increasing threat to human and animal health, necessitating research on natural immunomodulators, such as plant extracts and probiotics. In vitro and ex vivo models offer valuable tools for experimental studies, facilitating the development of alternative antimicrobial agents.
Article
Food Science & Technology
Desalew Tadesse, Negussie Retta, Mekonnen Girma, Nicholas Ndiwa, Tadelle Dessie, Olivier Hanotte, Paulos Getachew, Dirk Dannenberger, Steffen Maak
Summary: Adding flaxseed can decrease feed oxidative stability and increase the antioxidant needs of chickens. This study evaluated the effects of feeding plant polyphenol extracts as an antioxidant alongside flaxseed on fatty acid content, oxidative stability, and lipid health indices in breast muscle of slow-growing Sasso T451A dual-purpose chicken.
Article
Agriculture, Dairy & Animal Science
Beatriz Batista Trigo, Natalia Fonseca Alves, Marco Milanesi, Jose Fernando Garcia, Endashaw Terefe, Olivier Hanotte, Abdulfatai Tijjani, Yuri Tani Utsunomiya
Summary: A structural variant (SV1) in the agouti signaling protein gene (ASIP) has been found to be strongly associated with hair coat darkness in specific regions of zebu cattle from the Nellore breed. Analysis of whole-genome sequences of zebu and taurine cattle revealed that ASIP-SV1 is commonly found in 45.9% of zebu cattle and 6.3% of taurine cattle, with the taurine cattle showing zebu introgression or being from crossbreeding. This study provides evidence of the widespread presence of ASIP-SV1 in both zebu populations and taurine cattle with zebu admixture.
Article
Cell Biology
Hussain Bahbahani, Sanaa Al-Zoubi, Fatima Ali, Arwa Afana, Mohammed Dashti, Abdulaziz Al-Ateeqi, David Wragg, Suzanne Al-Bustan, Faisal Almathen
Summary: This study investigates the natural selection signatures in the mitochondrial DNA of different dromedary camel populations. The findings reveal adaptive divergence between Old World and New World camels, with evidence of purifying selection among Old World camel species. A total of 89 codons, known to impact the physiochemical properties of proteins, were found to be under positive selection in the Camelidae family.
Article
Agriculture, Dairy & Animal Science
Aleksandra Dunislawska, Aleksandra Beldowska, Olha Yatsenko, Maria Siwek
Summary: Mitochondria play a crucial role in cellular functions, and the gut microbiota may improve their functioning. This study investigates the effects of prebiotics on gene expression in the intestinal mucosa and cecal tonsils of broiler chickens.
Article
Multidisciplinary Sciences
M. Parejo, A. Talenti, M. Richardson, A. Vignal, M. Barnett, D. Wragg
Summary: This study utilized the unique characteristics of haploid honey bee drones and high-quality genetic data to establish the haplotype resource AmelHap. It demonstrated the utility of AmelHap in genotype imputation, association studies, population genetic analyses, and evolutionary analyses.
Article
Food Science & Technology
Desalew Tadesse, Negussie Retta, Mekonnen Girma, Nicholas Ndiwa, Tadelle Dessie, Olivier Hanotte, Paulos Getachew, Dirk Dannenberger, Steffen Maak
Summary: This study investigated the effects of feeding flaxseed and plant polyphenol extracts on fatty acid content, oxidative stability, and lipid health indices in eggs. The results showed that the inclusion of flaxseed and moderate doses of plant polyphenol extracts significantly increased the content of n-3 polyunsaturated fatty acids in eggs and improved lipid health indices.
Article
Biodiversity Conservation
Endashaw Terefe, Gurja Belay, Abdulfatai Tijjani, Jianlin Han, Olivier Hanotte
Summary: This study analyzed the whole genome sequences of 151 samples from 14 Ethiopian indigenous cattle populations to assess genomic diversity, differentiation, and selection signatures. The results revealed high genomic differentiation between Ethiopian and non-Ethiopian cattle populations, as well as low differentiation and inbreeding within Ethiopian cattle populations. Furthermore, candidate genes associated with various biological functions and molecular pathways were identified in Ethiopian cattle.
Review
Agriculture, Dairy & Animal Science
Sumaya Kambal, Abdulfatai Tijjani, Sabah A. E. Ibrahim, Mohamed-Khair A. Ahmed, Joram M. Mwacharo, Olivier Hanotte
Summary: The review summarizes the research on genomic regions under positive selection in indigenous African cattle breeds, highlighting candidate genes and genome regions associated with adaptation to extreme environments and environmental challenges such as heat stress, infectious diseases, and high altitude. The review also emphasizes the importance of identifying candidate causative variants controlling these traits and provides guidance for future targeted genome studies. The highest numbers of candidate regions are found on BTA3, BTA5, and BTA7, overlapping with genes involved in various biological functions and pathways.
Biographical-Item
Biochemistry & Molecular Biology
Pablo Orozco-terWengel, Eric Coissac, Olivier Hanotte, Francois Pompanon, Paul Sunnucks, Pierre Taberlet
Article
Biotechnology & Applied Microbiology
Ramesha N. Wishna-Kadawarage, Martin Jensen, Szymon Powalowski, Rita M. Hickey, Maria Siwek
Summary: Synbiotics have been extensively studied to enhance gut health in humans and animals. The success of synbiotics depends on the compatibility between prebiotics and probiotics. Certain plant extracts with antimicrobial and prebiotic properties show potential in combination with probiotics to improve gut health, termed as prophybiotics. This study aimed to identify compatible combinations of prebiotics and six strains of lactic acid bacteria (LAB) for synbiotic/prophybiotic use. The results indicated that turmeric and garlic have broad potential as prophybiotics, while the studied prebiotics have limited use for synbiotics with these LAB strains.
INTERNATIONAL MICROBIOLOGY
(2023)