Journal
ANIMAL GENETICS
Volume 40, Issue 4, Pages 553-555Publisher
WILEY
DOI: 10.1111/j.1365-2052.2009.01865.x
Keywords
horse; horse chromosome 5; osteochondrosis; quantitative trait locus
Funding
- German Research Council, DFG, Bonn [DI 333/12-2]
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P>In this report, we provide 29 new informative microsatellites distributed over a region of 21 Mb on horse chromosome (ECA) 5 and refine a quantitative trait locus (QTL) for fetlock osteochondrosis dissecans (OCD) to a genome-wide significant interval between 78.03 and 90.23 Mb on ECA5. Genotyping was performed in 211 Hanoverian warmblood horses from 14 paternal half-sib groups. Within this OCD-QTL, collagen type XXIV alpha 1 was identified as a potential functional candidate gene for equine osteochondrosis. This report is a further step towards unravelling the genes that cause equine osteochondrosis.
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