Exploring glia to better understand Alzheimer’s disease

Monitoring Ca 2+ elevations in individual astrocytes upon local release of amyloid beta in acute brain slices

(2018) Olga Tyurikova et al.   BRAIN RESEARCH BULLETIN

Human astrocytes in the diseased brain

(2018) Elena Dossi et al.   BRAIN RESEARCH BULLETIN

Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum

(2018) Junsung Woo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P2Y12R-Dependent Translocation Mechanisms Gate the Changing Microglial Landscape

(2018) Ukpong B. Eyo et al.   Cell Reports

Innate immune memory in the brain shapes neurological disease hallmarks

(2018) Ann-Christin Wendeln et al.   NATURE

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

(2017) Petra Füger et al.   NATURE NEUROSCIENCE

ApoE4 Accelerates Early Seeding of Amyloid Pathology

(2017) Chia-Chen Liu et al.   NEURON

Altered GABAergic Signaling in Brain Disease at Various Stages of Life

(2017) Yoo Sung Kim et al.   Experimental Neurobiology

Decreased Glial GABA and Tonic Inhibition in Cerebellum of Mouse Model for Attention-Deficit/Hyperactivity Disorder (ADHD)

(2017) Yoo Sung Kim et al.   Experimental Neurobiology

Fibrillar Amyloid-  Peptides Activate Microglia via TLR2: Implications for Alzheimer's Disease

(2014) M. Jana et al.   JOURNAL OF IMMUNOLOGY

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers

(2012) Sadayuki Hashioka et al.   NEUROPHARMACOLOGY

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

(2011) Tetsuya Mizuno et al.   AMERICAN JOURNAL OF PATHOLOGY

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

(2011) Min Song et al.   Journal of Neuroinflammation

Microglia Mediate the Clearance of Soluble A  through Fluid Phase Macropinocytosis

(2009) S. Mandrekar et al.   JOURNAL OF NEUROSCIENCE

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON