Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Bromelain nanoparticles protect against 7,12-dimethylbenz[a]anthracene induced skin carcinogenesis in mouse model

(2015) Priyanka Bhatnagar et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The role of epigenetics in colorectal cancer

(2014) Fabio Coppedè   Expert Review of Gastroenterology & Hepatology

The chemopreventive action of bromelain, from pineapple stem (Ananas comosusL.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects

(2013) Barbara Romano et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diet, Genes, and Microbes

(2013) Diane F. Birt et al.   TOXICOLOGIC PATHOLOGY

The prognostic value of KRAS mutations in patients with colorectal cancer

(2012) YASUHIRO INOUE et al.   ONCOLOGY REPORTS

KRAS Gene Mutation in Colorectal Cancer Is Correlated With Increased Proliferation and Spontaneous Apoptosis

(2011) Xiuli Liu et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Bromelain-Induced Apoptosis in GI-101A Breast Cancer Cells

(2011) Sivanesan Dhandayuthapani et al.   JOURNAL OF MEDICINAL FOOD

Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G2/M arrest to apoptosis

(2011) Kulpreet Bhui et al.   MOLECULAR CARCINOGENESIS

Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells

(2010) Kulpreet Bhui et al.   BIOFACTORS

Bromelain’s activity and potential as an anti-cancer agent: Current evidence and perspectives

(2009) Katya Chobotova et al.   CANCER LETTERS

Natural products and colon cancer: current status and future prospects

(2008) Subapriya Rajamanickam et al.   DRUG DEVELOPMENT RESEARCH

Oral Bromelain Attenuates Inflammation in an Ovalbumin-Induced Murine Model of Asthma

(2007) Eric R. Secor et al.   Evidence-based Complementary and Alternative Medicine