Article
Dentistry, Oral Surgery & Medicine
Blanca Estevez-Arroyo, Ignacio Gomez-Mendo, Martin Romero-Maroto, Enrique Solano-Reina, Alejandro Iglesias-Linares
Summary: Patients with Van der Woude syndrome exhibit specific craniofacial characteristics, including a tendency towards vertical growth pattern, skeletal class II caused by mandibular retrognathism, retruded and retroclined lower incisors, increased interincisal angulation, an open nasolabial angle, and a more protruding lower lip.
Article
Cell & Tissue Engineering
H. J. Kok, C. N. Crowder, L. Koo Min Chee, H. Y. Choi, N. Lin, E. R. Barton
Summary: IGF-I plays a crucial role in muscle and bone development, acting as a primary mediator of growth hormone actions. Studies using mice with muscle-specific IGF-I overexpression have shown that increased muscle IGF-I can indirectly affect craniofacial growth through IGF-I-dependent increases in muscle hypertrophy, which has implications for therapeutic strategies for craniofacial disorders.
EUROPEAN CELLS & MATERIALS
(2021)
Article
Dermatology
Fernando Garcia-Souto, Javier del Boz, Maria Colmenero-Sendra, Juan Polo-Padillo
Summary: This study aimed to describe the clinical characteristics of patients with craniofacial hyperhidrosis and compare them with those at other locations. The study found significant differences in terms of age, onset of hyperhidrosis, affected areas, and generalized hyperhidrosis among patients with craniofacial hyperhidrosis. However, there were no significant differences in the effectiveness and side effects of oral oxybutynin between different locations. Patients with exclusively facial hyperhidrosis showed greater adherence to treatment.
DERMATOLOGIC THERAPY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Fabio Savoldi, Francesca Del Re, Ingrid Tonni, Min Gu, Domenico Dalessandri, Luca Visconti
Summary: Cleidocranial dysplasia (CCD) is a rare skeletal syndrome that affects craniofacial and dental development. This study found that CCD patients have a shortening of the cranial base, leading to protrusion of the mandible and maxilla, despite a reduced length. Additionally, CCD patients have reduced mandibular divergence, decreased overbite, and retro-inclination of lower incisors.
DENTOMAXILLOFACIAL RADIOLOGY
(2022)
Article
Genetics & Heredity
Vivian Reinhold, Stina Syrjanen, Minna Kankuri-Tammilehto
Summary: This study reports a severe case of oligodontia in a female patient with the EDA gene variant c.742-2A>G. The results strongly suggest that this variant is pathogenic and the oligodontia in the patient is exceptionally severe. Early identification of this variant is crucial for planning adequate treatment and follow-up.
MOLECULAR GENETICS & GENOMIC MEDICINE
(2023)
Article
Medicine, General & Internal
Layla Damen, Melitza S. M. Elizabeth, Stephany H. Donze, Sjoerd A. A. van den Berg, Laura C. G. de Graaff, Anita C. S. Hokken-Koelega
Summary: In children with Prader-Willi syndrome receiving GH treatment, high immunoreactive IGF-I levels are often observed, while free IGF-I levels are low, indicating a significant discrepancy between the two.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Pediatrics
Camilla Hansen, Agneta Markstrom, Liselotte Sonnesen
Summary: Dento-craniofacial characteristics such as anterior open bite, large overjet due to mandibular retrognathia, cross bite, and narrow and high palate can predispose to SDB in non-syndromic children. Facial characteristics predisposing to SDB can be a convex facial profile, extended head posture, mouth breathing and general adenoidal face. Interdisciplinary collaboration between medical doctors and dentists can prove valuable in diagnostics, prevention and treatment of SDB in non-syndromic children.
Review
Oncology
Jumanah Qedair, Ali S. Haider, Kishore Balasubramanian, Paolo Palmisciano, Taimur Hassan, Ataollah Shahbandi, Mohammadmahdi Sabahi, Abdurrahman F. Kharbat, Hussam Abou-Al-Shaar, Kenny Yu, Aaron A. Cohen-Gadol, Tarek Y. El Ahmadieh, Othman Bin-Alamer
Summary: Despite the disfiguring nature of orbital exenteration (OE), it has been used as a surgical intervention for craniofacial lesions, particularly in advanced or recurrent tumors. However, large studies investigating the clinical and survival outcomes are lacking. This study aims to review the literature on the clinical characteristics and outcomes of patients who underwent OE. A positive surgical margin after OE was found to be significantly associated with worse overall survival (OS), while other factors such as sex, tumor recurrence, type of OE, and tumor histopathology did not show significant effects on OS.
Review
Endocrinology & Metabolism
David L. Russell-Jones, Ewan J. Hutchison, Graham A. Roberts
Summary: In the past, people with diabetes treated with insulin have often been banned from safety-critical occupations due to fear of incapacitation from hypoglycemia. However, recent advances in insulin therapies and monitoring techniques have challenged these stereotypes. The aviation sector has paved the way for allowing pilots to fly while on insulin, and more countries are changing their minds due to increasing evidence of safety.
DIABETES OBESITY & METABOLISM
(2021)
Article
Environmental Sciences
Pei-Ching Chang, Shiao-Yu Lin
Summary: The article discusses the oral issues experienced by a boy diagnosed with rhabdomyosarcoma and the dental treatments he underwent during his treatment process. It also mentions the long-term effects of cancer therapy, including facial deformity, faced by the patient after years of treatment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Chemistry, Physical
Marianna Pires Barbosa, Tiago Braga Rabello, Eduardo Moreira da Silva
Summary: The present study aimed to analyze the influence of adhesive strategy, the type of dental composite, and polishing time on marginal gap formation at the tooth-composite interface. The results suggest that selective enamel etching (SEE) is a better strategy for reducing marginal gap formation, regardless of the time in which the restoration is polished.
Article
Hematology
Adam S. Kittai, Ying Huang, Kyle A. Beckwith, Seema A. Bhat, David A. Bond, John C. Byrd, Daniel Goldstein, Michael R. Grever, Cecelia Miller, Kerry A. Rogers, Max Yano, Jennifer A. Woyach
Summary: This retrospective analysis found that progression on treatment, higher LDH levels, and lymphadenopathy without lymphocytosis were independent prognostic factors for the development of Richter's Transformation in CLL patients treated with ibrutinib. Additionally, the prognosis for Richter's Transformation remained poor.
AMERICAN JOURNAL OF HEMATOLOGY
(2023)
Article
Nutrition & Dietetics
Philippe P. Hujoel
Summary: This report explores how the American Dental Association ignored evidence linking pediatric vitamin D deficiencies with dental caries, showing how professional organizations of clinical specialists have the power to create standards of care that may harm public health by ignoring key evidence.
Article
Dentistry, Oral Surgery & Medicine
Florence Danneels, Anna Verdonck, Karlijne Indencleef, Dominique Declerck, Guy Willems, Maria Cadenas De Llano-Perula
Summary: The study found significant facial differences in the nose and mouth area using 3D facial scans for WBS identification, while cephalometric aspects and panoramic radiographs also revealed significant differences in dental characteristics. 3D imaging can be an effective method for early diagnosis of WBS and help in planning appropriate medical, dental, and orthodontic treatments.
ORTHODONTICS & CRANIOFACIAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Andre Alexis Diaz-Quevedo, Hella Maomy Lucero Castillo-Quispe, Katherine Joselyn Atoche-Socola, Luis Ernesto Arriola-Guillen
Summary: Children and adolescents with Down syndrome (DS) exhibit craniofacial and oral characteristics such as reduced dimensions of facial bones and a higher prevalence of periodontal diseases. These abnormalities can lead to Class III malocclusion and impact their quality of life by causing difficulties in swallowing, talking, eating, and breathing through the nose.
JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY
(2021)