4.3 Article

Neutrophil-to-Lymphocyte Ratio is Associated With Severity of Coronary Artery Ectasia

Journal

ANGIOLOGY
Volume 65, Issue 2, Pages 147-151

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/0003319713488932

Keywords

coronary artery ectasia; inflammation; neutrophil to lymphocyte ratio

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We investigated the association between coronary artery ectasia (CAE) and Neutrophil-to-lymphocyte ratio (NLR), an indicator of the inflammatory state. The study population included 434 patients (247 males, mean age 62 +/- 10 years) including 230 patients with isolated CAE and 104 patients with coronary artery disease and 100 patientss with normal coronary arteries. The NLR was measured at admission and 30 days after coronary angiography in all the patients. The NLR was significantly higher in patients with CAE than those with normal coronary arteries (2.2 +/- 0.6-1.3 +/- 0.6, P < .001). Linear regression analyses revealed that NLR (coefficient beta = -.61, P < .001) was significantly associated with severity of CAE. The NLR is significantly higher in patients with CAE compared to controls with normal coronary arteries, and NLR is associated with severity of CAE.

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