Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo

The promotion of angiogenesis by growth factors integrated with ECM proteins through coiled-coil structures

(2013) Yasmine Assal et al.   BIOMATERIALS

Acute Depletion of Endothelial β3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice

(2013) Veronica Steri et al.   CIRCULATION RESEARCH

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Modulation of CXCL-8 expression in human melanoma cells regulates tumor growth, angiogenesis, invasion, and metastasis

(2012) Sheng Wu et al.   Cancer Medicine

The adaptor protein Shc integrates growth factor and ECM signaling during postnatal angiogenesis

(2011) D. T. Sweet et al.   BLOOD

Molecular Mechanisms Controlling Vascular Lumen Formation in Three-Dimensional Extracellular Matrices

(2011) Anastasia Sacharidou et al.   CELLS TISSUES ORGANS

The role of β3-integrins in tumor angiogenesis: context is everything

(2011) Stephen D Robinson et al.   CURRENT OPINION IN CELL BIOLOGY

Insulin-like Growth Factor Binding Protein-4 Differentially Inhibits Growth Factor-induced Angiogenesis

(2011) Liangru W. Contois et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin αvβ3-Mediated FGF-2 Release

(2011) Theres Hennig et al.   JOURNAL OF VASCULAR RESEARCH

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology

(2010) James Beattie et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype

(2009) N. Almog et al.   CANCER RESEARCH

Tumor and Host-Mediated Pathways of Resistance and Disease Progression in Response to Antiangiogenic Therapy

(2009) J. M. L. Ebos et al.   CLINICAL CANCER RESEARCH

The Angiogenic Switch: Implications in the Regulation of Tumor Dormancy

(2009) L. Moserle et al.   CURRENT MOLECULAR MEDICINE

Activation of tumor cell integrin  v 3 controls angiogenesis and metastatic growth in the brain

(2009) M. Lorger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrins as “functional hubs” in the regulation of pathological angiogenesis

(2009) Liangru Contois et al.   SEMINARS IN CANCER BIOLOGY

Micro-CT of Corrosion Casts for Use in the Computer-Aided Design of Microvasculature

(2009) William Lafayette Mondy et al.   TISSUE ENGINEERING PART C-METHODS

Regulation of tumor dormancy as a function of tumor-mediated paracrine regulation of stromal Tsp-1 and VEGF expression 

(2008) SOO-YOUNG KANG et al.   APMIS

The angiogenic response is dictated by β3integrin on bone marrow–derived cells

(2008) Weiyi Feng et al.   JOURNAL OF CELL BIOLOGY

Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients

(2008) Jessie Z Yu et al.   Journal of Translational Medicine

Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

(2008) Yeriel Estrada et al.   Pigment Cell & Melanoma Research