Endoglin and activin receptor-like kinase 1 heterozygous mice have a distinct pulmonary and hepatic angiogenic profile and response to anti-VEGF treatment

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

(2013) P. R. Lawler et al.   Cold Spring Harbor Perspectives in Medicine

Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation Is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse

(2012) Eun-Jung Choi et al.   CEREBROVASCULAR DISEASES

Bevacizumab in Patients With Hereditary Hemorrhagic Telangiectasia and Severe Hepatic Vascular Malformations and High Cardiac Output

(2012) Sophie Dupuis-Girod et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cardiovascular and Systemic MicrovascularEffects of Anti-Vascular Endothelial Growth Factor Therapy for Cancer

(2012) J. Todd Belcik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Oxidative Stress Contributes to Endothelial Dysfunction in Mouse Models of Hereditary Hemorrhagic Telangiectasia

(2012) Mirjana Jerkic et al.   Oxidative Medicine and Cellular Longevity

Bevacizumab Attenuates VEGF-Induced Angiogenesis and Vascular Malformations in the Adult Mouse Brain

(2012) Espen J. Walker et al.   STROKE

Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress

(2011) Mirjana Jerkic et al.   CARDIOVASCULAR RESEARCH

Micro-ultrasound for preclinical imaging

(2011) F. S. Foster et al.   Interface Focus

Clinical Outcomes of Pulmonary Arterial Hypertension in Patients Carrying anACVRL1(ALK1) Mutation

(2010) Barbara Girerd et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment

(2010) Claire L. Shovlin   BLOOD REVIEWS

Stimulatory effects of the multi-kinase inhibitor sorafenib on human bladder cancer cells

(2010) A Rose et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

(2010) Marwa Mahmoud et al.   CIRCULATION RESEARCH

Circulating angiopoietins in idiopathic pulmonary arterial hypertension

(2010) Philipp Kümpers et al.   EUROPEAN HEART JOURNAL

Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47

(2010) Sukhbir Kaur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension

(2010) Cristhiaan D Ochoa et al.   Journal of Cardiothoracic Surgery

Hereditary hemorrhagic telangiectasia: from molecular biology to patient care

(2010) S. DUPUIS-GIROD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Ocular manifestations in hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease): A case-series

(2010) Michele Rinaldi et al.   OPHTHALMIC GENETICS

Signaling by members of the TGF-β family in vascular morphogenesis and disease

(2010) Evangelia Pardali et al.   TRENDS IN CELL BIOLOGY

VEGF Induces More Severe Cerebrovascular Dysplasia in Eng+/− than in Alk1+/− Mice

(2010) Qi Hao et al.   Translational Stroke Research

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Spontaneous Adult-Onset Pulmonary Arterial Hypertension Attributable to Increased Endothelial Oxidative Stress in a Murine Model of Hereditary Hemorrhagic Telangiectasia

(2009) Mourad Toporsian et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells

(2009) E. S. Shao et al.   BLOOD

Bevacizumab in Hereditary Hemorrhagic Telangiectasia

(2009) Prithviraj Bose et al.   NEW ENGLAND JOURNAL OF MEDICINE

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats

(2008) Marc Mejias et al.   HEPATOLOGY

Bevacizumab reverses need for liver transplantation in hereditary hemorrhagic telangiectasia

(2008) Andrew Mitchell et al.   LIVER TRANSPLANTATION

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE

Early-life pulmonary arterial hypertension with subsequent development of diffuse pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia type 1

(2007) C J Mache et al.   THORAX