A Unified Approach to Couple Aromatic Heteronucleophiles to Azines and Pharmaceuticals

C–N Cross-Coupling via Photoexcitation of Nickel–Amine Complexes

(2018) Chern-Hooi Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Selective Switching Strategies to Functionalize Polyazines

(2018) Ryan D. Dolewski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals

(2018) J. Luke Koniarczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

A Strategy to Aminate Pyridines, Diazines, and Pharmaceuticals via Heterocyclic Phosphonium Salts

(2018) Chirag Patel et al.   ORGANIC LETTERS

Selective formation of heteroaryl thioethers via a phosphonium ion coupling reaction

(2018) Ryan G. Anderson et al.   TETRAHEDRON

Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

(2016) Paula Ruiz-Castillo et al.   CHEMICAL REVIEWS

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Selective Functionalization of Pyridines via Heterocyclic Phosphonium Salts

(2016) Michael C. Hilton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

(2016) Emily B. Corcoran et al.   SCIENCE

First ever observation of the intermediate of phosphonium salt and ylide hydrolysis: P-hydroxytetraorganophosphorane

(2015) Peter A. Byrne et al.   CHEMICAL COMMUNICATIONS

Organometallic palladium reagents for cysteine bioconjugation

(2015) Ekaterina V. Vinogradova et al.   NATURE

FDA-approved small-molecule kinase inhibitors

(2015) Peng Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Transition-Metal-Catalyzed CS Bond Coupling Reaction

(2014) Chin-Fa Lee et al.   Chemistry-An Asian Journal

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iridium-Catalyzed C–H Borylation of Heteroarenes: Scope, Regioselectivity, Application to Late-Stage Functionalization, and Mechanism

(2014) Matthew A. Larsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxygen nucleophiles as reaction partners in photoinduced, copper-catalyzed cross-couplings: O-arylations of phenols at room temperature

(2014) Yichen Tan et al.   Chemical Science

An efficient method for the synthesis of heteroaryl C–O bonds in the absence of added transition metal catalysts

(2014) Katie Walsh et al.   RSC Advances

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

(2013) Marcus Baumann et al.   Beilstein Journal of Organic Chemistry

A New Family of Nucleophiles for Photoinduced, Copper-Catalyzed Cross-Couplings via Single-Electron Transfer: Reactions of Thiols with Aryl Halides Under Mild Conditions (O °C)

(2013) Christopher Uyeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Versatile Approach to Ullmann C–N Couplings at Room Temperature: New Families of Nucleophiles and Electrophiles for Photoinduced, Copper-Catalyzed Processes

(2013) Daniel T. Ziegler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced Ullmann C-N Coupling: Demonstrating the Viability of a Radical Pathway

(2012) S. E. Creutz et al.   SCIENCE

A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

(2011) E. Lee et al.   SCIENCE

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?

(2009) Kristy J. Gotink et al.   ANGIOGENESIS

Protein kinase inhibitors: contributions from structure to clinical compounds

(2009) Louise N. Johnson   QUARTERLY REVIEWS OF BIOPHYSICS

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION