Three-Dimensional Heterocycles by Iron-Catalyzed Ring-Closing Sulfoxide Imidation

Metal–organic layers stabilize earth-abundant metal–terpyridine diradical complexes for catalytic C–H activation

(2018) Zekai Lin et al.   Chemical Science

Rhodium(iii)-catalyzed annulative coupling between arenes and sulfoxonium ylides via C–H activation

(2018) Guangfan Zheng et al.   Organic Chemistry Frontiers

Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery

(2017) Marcus Frings et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Convenient, Mild, and Green Synthesis of NH-Sulfoximines in Flow Reactors

(2017) Leonardo Degennaro et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry

(2017) Tanaji T. Talele   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Synthesis of N-Heterocycles via Direct C(sp3)–H Amination Using an Air-Stable Iron(III) Species with a Redox-Active Ligand

(2017) Bidraha Bagh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

(2017) Georg Karpel-Massler et al.   NEUROCHEMICAL RESEARCH

Tetrahydrobenzo[c]thieno[2,1-e]isothiazole 4-Oxides: Three-Dimensional Heterocycles as Cross-Coupling Building Blocks

(2017) Philip Lamers et al.   ORGANIC LETTERS

Rhodium-Catalyzed [4 + 3] Annulations of Sulfoximines with α,β-Unsaturated Ketones Leading to 1,2-Benzothiazepine 1-Oxides

(2017) Jian Wen et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed Ortho Halogenations of N-Acylsulfoximines and Synthetic Applications toward Functionalized Sulfoximine Derivatives

(2017) Ying Cheng et al.   ORGANIC LETTERS

1,2-Benzothiazines from Sulfoximines and Allyl Methyl Carbonate by Rhodium-Catalyzed Cross-Coupling and Oxidative Cyclization

(2017) Jian Wen et al.   ORGANIC LETTERS

Development and Demonstration of a Safer Protocol for the Synthesis of 5-Aryltetrazoles from Aryl Nitriles

(2017) Daniel S. Treitler et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Use of a Curtius Rearrangement as Part of the Multikilogram Manufacture of a Pyrazine Building Block

(2017) Alan Steven et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Straightforward Strategies for the Preparation of NH-Sulfox­imines: A Serendipitous Story

(2017) James Bull et al.   SYNLETT

N-Arylated Sulfoximines as Cross-Coupling Building Blocks

(2017) Anne-Katrin Bachon et al.   ADVANCED SYNTHESIS & CATALYSIS

Benzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential

(2016) Philip Lamers et al.   ADVANCED SYNTHESIS & CATALYSIS

1,2-Thiazines: One-Pot Syntheses Utilizing Mono and Diaza Analogs of Sulfones

(2016) Rebekka Anna Bohmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed ortho -Amidations in the Preparation of Thiadiazine 1-Oxides

(2016) Ying Cheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Robust and Porous β-Diketiminate-Functionalized Metal–Organic Frameworks for Earth-Abundant-Metal-Catalyzed C–H Amination and Hydrogenation

(2016) Nathan C. Thacker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Halocyclizations of Unsaturated Sulfoximines

(2016) Han Wang et al.   ORGANIC LETTERS

Building Block Approach for the Synthesis of Sulfoximines

(2016) Anne-Dorothee Steinkamp et al.   ORGANIC LETTERS

Synthesis of 1,2-Benzothiazines by a Rhodium-Catalyzed Domino C–H Activation/Cyclization/Elimination Process from S-Aryl Sulfoximines and Pyridotriazoles

(2016) Woo Hyung Jeon et al.   ORGANIC LETTERS

Iron-Catalyzed Amination of Sulfides and Sulfoxides with Azides in Photochemical Continuous Flow Synthesis

(2016) Hélène Lebel et al.   ACS Catalysis

Active Species and Mechanistic Pathways in Iron-Catalyzed C–C Bond-Forming Cross-Coupling Reactions

(2016) Carlo Cassani et al.   ACS Catalysis

Stereoselective synthesis of 4-aminobenzo[c][1,2]thiazine via modification of the Harmata benzothiazine synthesis

(2016) S. R. K. Battula et al.   RSC Advances

Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

(2016) Alois Fürstner   ACS Central Science

Iron-Catalyzed C–C Cross-Couplings Using Organometallics

(2016) Amandine Guérinot et al.   Topics in Current Chemistry

How Low Does Iron Go? Chasing the Active Species in Fe-Catalyzed Cross-Coupling Reactions

(2015) Robin B. Bedford   ACCOUNTS OF CHEMICAL RESEARCH

Transition-Metal-Catalyzed C–N Bond Forming Reactions Using Organic Azides as the Nitrogen Source: A Journey for the Mild and Versatile C–H Amination

(2015) Kwangmin Shin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Regioselective Syntheses of 1,2-Benzothiazines by Rhodium-Catalyzed Annulation Reactions

(2015) Ying Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium- and palladium-catalyzed consecutive coupling and cyclization of aromatic sulfoximines with phenylboronic acids: an efficient route to dibenzothiazines

(2015) Ravi Kiran Chinnagolla et al.   CHEMICAL COMMUNICATIONS

Iron Catalysis in Organic Synthesis

(2015) Ingmar Bauer et al.   CHEMICAL REVIEWS

Sulfur imidations: access to sulfimides and sulfoximines

(2015) Vincent Bizet et al.   CHEMICAL SOCIETY REVIEWS

Designing novel building blocks is an overlooked strategy to improve compound quality

(2015) Frederick W. Goldberg et al.   DRUG DISCOVERY TODAY

Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions

(2015) Bernhard Gutmann et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Development of a Scalable Process for the Crop Protection Agent Isoclast

(2015) Kim E. Arndt et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

α-MsO/TsO/Cl Ketones as Oxidized Alkyne Equivalents: Redox-Neutral Rhodium(III)-Catalyzed CH Activation for the Synthesis of N-Heterocycles

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorinated sulfoximines: syntheses, properties and applications

(2014) Vincent Bizet et al.   CHEMICAL SOCIETY REVIEWS

Fluorinated Sulfoximines: Preparation, Reactions and Applications

(2014) Xiao Shen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Sulfoximines: A Neglected Opportunity in Medicinal Chemistry

(2013) Ulrich Lücking   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Oxidative Annulation of Sulfoximines and Alkynes as an Approach to 1,2-Benzothiazines

(2013) Wanrong Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Nitrene Transfer to Sulfides Catalyzed by a Chiral Iron Complex

(2013) Jun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron-Catalyzed Imidative Kinetic Resolution of Racemic Sulfoxides

(2013) Jun Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nonheme Iron-Mediated Amination of C(sp3)–H Bonds. Quinquepyridine-Supported Iron-Imide/Nitrene Intermediates by Experimental Studies and DFT Calculations

(2013) Yungen Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complex N-Heterocycle Synthesis via Iron-Catalyzed, Direct C-H Bond Amination

(2013) E. T. Hennessy et al.   SCIENCE

Iron-Catalyzed Intramolecular Allylic C–H Amination

(2012) Shauna M. Paradine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron(II) Bromide-Catalyzed Intramolecular C–H Bond Amination [1,2]-Shift Tandem Reactions of Aryl Azides

(2012) Quyen Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scale-up of Azide Chemistry: A Case Study

(2012) Francisco González-Bobes et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Escape from Flatland 2: complexity and promiscuity

(2012) Frank Lovering   MedChemComm

Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners

(2011) Ranjan Jana et al.   CHEMICAL REVIEWS

What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

(2011) W. Patrick Walters et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron(II) Triflate as a Catalyst for the Synthesis of Indoles by Intramolecular C−H Amination

(2011) Julien Bonnamour et al.   ORGANIC LETTERS

Synthesis of Sulfoximines and Sulfilimines with Aryl and Pyrazolylmethyl Substituents

(2010) Olga García Mancheño et al.   ADVANCED SYNTHESIS & CATALYSIS

Heteroaromatic Rings of the Future

(2009) William R. Pitt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

A new iron age

(2009) Carsten Bolm   Nature Chemistry

Iron(II) Triflate as an Efficient Catalyst for the Imination of Sulfoxides

(2009) Olga García Mancheño et al.   ORGANIC LETTERS

The Promise and Challenge of Iron-Catalyzed Cross Coupling

(2008) Benjamin D. Sherry et al.   ACCOUNTS OF CHEMICAL RESEARCH