Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 53, Issue 20, Pages 5078-5082Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201311241
Keywords
alkenes; aryl migration; desulfonylation; difunctionalization; radicals
Categories
Funding
- European Research Council (ERC) [307948]
- European Research Council (ERC) [307948] Funding Source: European Research Council (ERC)
Ask authors/readers for more resources
Two radical-mediated processes of activated alkenes, namely arylphosphonylation and arylazidation, are described. The difunctionalization of alkenes by a tandem process that involves radical addition, 1,4-aryl migration, and desulfonylation generates -aryl--heterofunctionalized amides bearing a quaternary stereocenter when the substituent on the nitrogen atom is an aryl group. Alternatively, heterooxindoles or spirobicycles can be obtained with excellent regioselectivity in the presence of an alkyl substituent on the nitrogen atom.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available