Dynamics of Intact Immunoglobulin G Explored by Drift-Tube Ion-Mobility Mass Spectrometry and Molecular Modeling

Time Resolved Native Ion-Mobility Mass Spectrometry to Monitor Dynamics of IgG4 Fab Arm Exchange and “Bispecific” Monoclonal Antibody Formation

(2013) François Debaene et al.   ANALYTICAL CHEMISTRY

The Role of Ion Mobility Spectrometry–Mass Spectrometry in the Analysis of Protein Reference Standards

(2013) Caroline Pritchard et al.   ANALYTICAL CHEMISTRY

Complementary MS Methods Assist Conformational Characterization of Antibodies with Altered S–S Bonding Networks

(2013) Lisa M. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Characterization of Therapeutic Antibodies and Related Products

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

The impact of mass spectrometry on the study of intact antibodies: from post-translational modifications to structural analysis

(2012) Natalie J. Thompson et al.   CHEMICAL COMMUNICATIONS

Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

(2012) Steven A. Berkowitz et al.   NATURE REVIEWS DRUG DISCOVERY

Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3-CH3 Interaction Strength

(2011) A. F. Labrijn et al.   JOURNAL OF IMMUNOLOGY

Resolving Disulfide Structural Isoforms of IgG2 Monoclonal Antibodies by Ion Mobility Mass Spectrometry

(2010) Dhanashri Bagal et al.   ANALYTICAL CHEMISTRY

Antibodies to watch in 2010

(2010) Janice M. Reichert   mAbs

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Human IgG4 Binds to IgG4 and Conformationally Altered IgG1 via Fc-Fc Interactions

(2009) T. Rispens et al.   JOURNAL OF IMMUNOLOGY

Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer

(2008) Bryan J. McCullough et al.   ANALYTICAL CHEMISTRY

Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass

(2008) Thomas M. Dillon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY