Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 4, Pages 1312-1315Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201410322
Keywords
amides; cross-coupling; dehydrogenation; esters; nickel
Categories
Funding
- UC Irvine
- National Institutes of Health [GM105938]
Ask authors/readers for more resources
By exploring a new mode of nickel-catalyzed cross-coupling, a method to directly transform both aromatic and aliphatic aldehydes into either esters or amides has been developed. The success of this oxidative coupling depends on the appropriate choice of catalyst and organic oxidant, including the use of either ,,-trifluoroacetophenone or excess aldehyde. Mechanistic data that supports a catalytic cycle involving oxidative addition into the aldehyde CH bond is also presented.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available