Structure and Function of an RNA-Reading Thermostable DNA Polymerase

The Importance of Additive and Non-Additive Mutational Effects in Protein Engineering

(2013) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

(2013) Elżbieta Nowak et al.   NUCLEIC ACIDS RESEARCH

Interactions of non-polar and “Click-able” nucleotides in the confines of a DNA polymerase active site

(2012) Samra Obeid et al.   CHEMICAL COMMUNICATIONS

Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides

(2012) Weina Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase

(2012) Samra Obeid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates

(2012) Konrad Bergen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

(2012) Karin Betz et al.   Nature Chemical Biology

A short adaptive path from DNA to RNA polymerases

(2012) C. Cozens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unlocking the Sugar “Steric Gate” of DNA Polymerases

(2011) Jessica A. Brown et al.   BIOCHEMISTRY

Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity

(2011) Samra Obeid et al.   CHEMBIOCHEM

Replication through an abasic DNA lesion: structural basis for adenine selectivity

(2010) Samra Obeid et al.   EMBO JOURNAL

Genome instability due to ribonucleotide incorporation into DNA

(2010) Stephanie A Nick McElhinny et al.   Nature Chemical Biology

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase

(2010) S. Obeid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA