Chemical Biology of Glycosylphosphatidylinositol Anchors

Streamlined access to conjugation-ready glycans by automated synthesis

(2012) Lenz Kröck et al.   Chemical Science

A General Method for Synthesis of GPI Anchors Illustrated by the Total Synthesis of the Low-Molecular-Weight Antigen from Toxoplasma gondii

(2011) Yu-Hsuan Tsai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of a Glycosylphosphatidylinositol Anchor of the Human Lymphocyte CD52 Antigen

(2011) Srinivas Burgula et al.   CHEMISTRY-A EUROPEAN JOURNAL

Novel applications for glycosylphosphatidylinositol-anchored proteins in pharmaceutical and industrial biotechnology

(2011) Günter Müller   MOLECULAR MEMBRANE BIOLOGY

Synthetic glycosylphosphatidylinositol (GPI) anchors: how these complex molecules have been made

(2011) Andrei V. Nikolaev et al.   NATURAL PRODUCT REPORTS

Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins

(2011) Yusuke Maeda et al.   PROGRESS IN LIPID RESEARCH

Chemical synthesis and functionalization of clickable glycosylphosphatidylinositol anchors

(2011) Benjamin M. Swarts et al.   Chemical Science

Synthetic Inositol Phosphoglycans Related to GPI Lack Insulin-Mimetic Activity

(2010) Marie-Lyn Hecht et al.   ACS Chemical Biology

Synthetic glycosylphosphatidylinositol microarray reveals differential antibody levels and fine specificities in children with mild and severe malaria

(2010) Marco Tamborrini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chemoenzymatic synthesis of glycosylphosphatidylinositol-anchored glycopeptides

(2010) Zhimeng Wu et al.   CHEMICAL COMMUNICATIONS

The biological activity of structurally defined inositol glycans

(2010) Meenakshi Goel et al.   Future Medicinal Chemistry

Application of electrospray mass spectrometry to the structural determination of glycosylphosphatidylinositol membrane anchors

(2010) I. R. E. Nett et al.   GLYCOBIOLOGY

Immunological reactions in response to apicomplexan glycosylphosphatidylinositols

(2010) F. Debierre-Grockiego et al.   GLYCOBIOLOGY

Binding ofToxoplasma gondiiGlycosylphosphatidylinositols to Galectin-3 Is Required for Their Recognition by Macrophages

(2010) Françoise Debierre-Grockiego et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of a Glycosylphosphatidylinositol Anchor Bearing Unsaturated Lipid Chains

(2010) Benjamin M. Swarts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sortase A-Catalyzed Transpeptidation of Glycosylphosphatidylinositol Derivatives for Chemoenzymatic Synthesis of GPI-Anchored Proteins

(2010) Zhimeng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome

(2010) Peter M Krawitz et al.   NATURE GENETICS

Synthetic Glycosylphosphatidylinositol as Tools for Glycoparasitology Research

(2010) Nahid Azzouz et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The role of the prion protein membrane anchor in prion infection

(2010) Suzette A. Priola et al.   Prion

Total synthesis of the fully lipidated glycosylphosphatidylinositol (GPI) anchor of malarial parasite Plasmodium falciparum

(2010) Asif Ali et al.   TETRAHEDRON

Comparative bioinformatics analysis of the mammalian and bacterial glycomes

(2010) Alexander Adibekian et al.   Chemical Science

Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system

(2009) Toni Kline et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness

(2009) Terry K. Smith et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

GPI Glycan Remodeling by PGAP5 Regulates Transport of GPI-Anchored Proteins from the ER to the Golgi

(2009) Morihisa Fujita et al.   CELL

Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins

(2009) Morihisa Fujita et al.   FEBS LETTERS

Sortase-Catalyzed Peptide−Glycosylphosphatidylinositol Analogue Ligation

(2009) Xueqing Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From carbohydrate leads to glycomimetic drugs

(2009) Beat Ernst et al.   NATURE REVIEWS DRUG DISCOVERY

Probing Enzymes Late in the Trypanosomal Glycosylphosphatidylinositol Biosynthetic Pathway with Synthetic Glycosylphosphatidylinositol Analogues

(2008) Michael D. Urbaniak et al.   ACS Chemical Biology

Semisynthesis of a Glycosylphosphatidylinositol-Anchored Prion Protein

(2008) Christian F. W. Becker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Plasmodium falciparum dolichol phosphate mannose synthase represents a novel clade

(2008) Hosam Shams-Eldin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins†

(2008) Margot G. Paulick et al.   BIOCHEMISTRY

Synthesis and biological evaluation of sperm CD52 GPI anchor and related derivatives as binding receptors of pore-forming CAMP factor

(2008) Xiaoming Wu et al.   CARBOHYDRATE RESEARCH

ProbingTrypanosoma bruceiGlycosylphosphatidylinositol Biosynthesis Using Novel Precursor-Analogues

(2008) Michael D. Urbaniak et al.   Chemical Biology & Drug Design

T cells and immunopathogenesis of experimental African trypanosomiasis

(2008) Henry Tabel et al.   IMMUNOLOGICAL REVIEWS

Biosynthesis, Remodelling and Functions of Mammalian GPI-anchored Proteins: Recent Progress

(2008) T. Kinoshita et al.   JOURNAL OF BIOCHEMISTRY

Reciprocal Control of Pyruvate Dehydrogenase Kinase and Phosphatase by Inositol Phosphoglycans

(2008) Patricia McLean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitors of UDP-Galactopyranose Mutase Thwart Mycobacterial Growth

(2008) Emily C. Dykhuizen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plasmodium falciparum glycosylphosphatidylinositol toxin interacts with the membrane of non-parasitized red blood cells: a putative mechanism contributing to malaria anemia

(2008) Norbert W. Brattig et al.   MICROBES AND INFECTION

Synthetic GPI array to study antitoxic malaria response

(2008) Faustin Kamena et al.   Nature Chemical Biology

Lipid remodeling of GPI-anchored proteins and its function

(2007) Morihisa Fujita et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Automated oligosaccharide synthesis

(2007) Peter H. Seeberger   CHEMICAL SOCIETY REVIEWS