Rapid Catalyst Identification for the Synthesis of the Pyrimidinone Core of HIV Integrase Inhibitors

Discovery of an  -Amino C-H Arylation Reaction Using the Strategy of Accelerated Serendipity

(2011) A. McNally et al.   SCIENCE

A Simple, Multidimensional Approach to High-Throughput Discovery of Catalytic Reactions

(2011) D. W. Robbins et al.   SCIENCE

Palladium-Catalyzed, Direct Boronic Acid Synthesis from Aryl Chlorides: A Simplified Route to Diverse Boronate Ester Derivatives

(2010) Gary A. Molander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Aerobic Oxidative Functionalization of an Arene C−H Bond: Evidence for an Aryl-Copper(III) Intermediate

(2010) Amanda E. King et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Second-Generation, Highly Efficient Manufacturing Route for the HIV Integrase Inhibitor Raltegravir Potassium

(2010) Guy R. Humphrey et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

MISER chromatography (multiple injections in a single experimental run): the chromatogram is the graph

(2010) Christopher J. Welch et al.   TETRAHEDRON-ASYMMETRY

2-Substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries

(2009) Vincent A. Boyd et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Looking Forward in Pharmaceutical Process Chemistry

(2009) I. W. Davies et al.   SCIENCE

A Polar Radical Pair Pathway To Assemble the Pyrimidinone Core of the HIV Integrase Inhibitor Raltegravir Potassium

(2008) Philip J. Pye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

(2008) Vincenzo Summa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient Cross-Coupling of Secondary Alkyltrifluoroborates with Aryl ChloridesReaction Discovery Using Parallel Microscale Experimentation

(2008) Spencer D. Dreher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY