Is There No End to the Total Syntheses of Strychnine? Lessons Learned in Strategy and Tactics in Total Synthesis

Die tödliche Brechnuss. Strychnin - von der Isolierung zur Totalsynthese

(2011) Klaus Roth   CHEMIE IN UNSERER ZEIT

The Relevance of Higher Plants in Lead Compound Discovery Programs

(2011) A. Douglas Kinghorn et al.   JOURNAL OF NATURAL PRODUCTS

Unraveling the Mechanism of Cascade Reactions of Zincke Aldehydes

(2011) Robert S. Paton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical C−H Functionalization of Quinones with Boronic Acids

(2011) Yuta Fujiwara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collective synthesis of natural products by means of organocascade catalysis

(2011) Spencer B. Jones et al.   NATURE

A synthesis of strychnine by a longest linear sequence of six steps

(2011) David B. C. Martin et al.   Chemical Science

A Short Formal Total Synthesis of Strychnine with a Samarium Diiodide Induced Cascade Reaction as the Key Step

(2010) Christine Beemelmanns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereoselective Samarium Diiodide Induced Ketyl Cyclisations of Indole and Pyrrole Derivatives - Scope and Limitations

(2010) Christine Beemelmanns et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Concise Total Syntheses of (±)-Strychnine and (±)-Akuammicine†

(2010) Gopal Sirasani et al.   JOURNAL OF ORGANIC CHEMISTRY

Aiming for the Ideal Synthesis

(2010) Tanja Gaich et al.   JOURNAL OF ORGANIC CHEMISTRY

Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis:In vivoand Mechanistic Studies on the Migrastatin Core Ether Analog

(2010) Thordur Oskarsson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C−H Arylation of Electron-Deficient Heterocycles with Arylboronic Acids

(2010) Ian B. Seiple et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Concise Formal Synthesis of Porothramycins A and B via Zincke Pyridinium Ring-Opening/Ring-Closing Cascade

(2010) Theo D. Michels et al.   ORGANIC LETTERS

Samarium Diiodide Mediated Reactions in Total Synthesis

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Natural Product Inspired Compound Collections

(2009) Kamal Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Impact of Natural Products on Developing New Anti-Cancer Agents†

(2009) Gordon M. Cragg et al.   CHEMICAL REVIEWS

Mitsunobu and Related Reactions: Advances and Applications

(2009) K. C. Kumara Swamy et al.   CHEMICAL REVIEWS

The art of total synthesis through cascade reactions

(2009) K. C. Nicolaou et al.   CHEMICAL SOCIETY REVIEWS

The economies of synthesis

(2009) Timothy Newhouse et al.   CHEMICAL SOCIETY REVIEWS

Total Synthesis of Strychnine

(2009) Miwako Mori   HETEROCYCLES

Inspirations, Discoveries, and Future Perspectives in Total Synthesis

(2009) K. C. Nicolaou   JOURNAL OF ORGANIC CHEMISTRY

Complex Polycyclic Lactams from Pericyclic Cascade Reactions of Zincke Aldehydes

(2009) Sarah E. Steinhardt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nine-Step Enantioselective Total Synthesis of (+)-Minfiensine

(2009) Spencer B. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Access to the Core of theStrychnos,AspidospermaandIbogaAlkaloids. A Short Synthesis of Norfluorocurarine

(2009) David B. C. Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Synthetic Studies Leading to Structural Revisions of Marine Natural Products

(2009) Yoshihide Usami   Marine Drugs

Structural revisions of natural products by total synthesis

(2009) Martin E. Maier   NATURAL PRODUCT REPORTS

Protecting-group-free synthesis as an opportunity for invention

(2009) Ian S. Young et al.   Nature Chemistry

Highly diastereoselective samarium diiodide induced cyclizations of new 3-substituted indole derivatives

(2009) Christine Beemelmanns et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Organocatalytic Diels-Alder Reactions

(2009) Pedro Merino et al.   SYNTHESIS-STUTTGART

Molecular rearrangements in the construction of complex molecules

(2009) Larry E. Overman   TETRAHEDRON

Asymmetric Organocatalysis: From Infancy to Adolescence

(2008) Alessandro Dondoni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Synthetic Entry to the PentacyclicStrychnosAlkaloid Family, Using a [4 + 2]-Cycloaddition/Rearrangement Cascade Sequence

(2008) Jutatip Boonsombat et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereocontrolled Synthesis ofZ-Dienes via an Unexpected Pericyclic Cascade Rearrangement of 5-Amino-2,4-pentadienals

(2008) Sarah E. Steinhardt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantiospecific Total Synthesis of the Hapalindoles, Fischerindoles, and Welwitindolinonesviaa Redox Economic Approach

(2008) Jeremy M. Richter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native glycine receptor subtypes and their physiological roles

(2008) Joseph W. Lynch   NEUROPHARMACOLOGY

Use of samarium diiodide in the field of asymmetric synthesis

(2008) Kovuru Gopalaiah et al.   NEW JOURNAL OF CHEMISTRY

Synthesis of δ-Tributylstannyl-α,β,γ,δ-Unsaturated Aldehydes from Pyridines

(2008) Theo D. Michels et al.   ORGANIC LETTERS

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH