Brønsted Acid Activation Strategy in Transition-Metal Catalyzed Asymmetric Hydrogenation of N-Unprotected Imines, Enamines, and N-Heteroaromatic Compounds

Dihydrophenanthridine: A New and Easily Regenerable NAD(P)H Model for Biomimetic Asymmetric Hydrogenation

(2012) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Active Metal-Free Catalysts for Hydrogenation of Unsaturated Nitrogen-Containing Compounds

(2011) Victor Sumerin et al.   ADVANCED SYNTHESIS & CATALYSIS

Intermolecular and Selective Synthesis of 2,4,5-Trisubstituted Oxazoles by a Gold-Catalyzed Formal [3+2] Cycloaddition

(2011) Paul W. Davies et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Additional Coordination Group Leads to Extremely Efficient Chiral Iridium Catalysts for Asymmetric Hydrogenation of Ketones

(2011) Jian-Hua Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Alkynylation of C1-Substituted C,N-Cyclic Azomethine Imines by CuI/Chiral Brønsted Acid Co-Catalyst

(2011) Takuya Hashimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulating the Acidity: Highly Acidic Brønsted Acids in Asymmetric Catalysis

(2011) Magnus Rueping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalysis: Hydrogen Bonding versus Ion Pairing in Imine Activation

(2011) Matthias Fleischmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Catalytic Hydrosilylation of Pyridines

(2011) Dmitry V. Gutsulyak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Asymmetric Hydrosilylation of Indoles: Combined Lewis Base and Brønsted Acid Activation

(2011) You-Cai Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Transition-Metal and Chiral Brønsted Acid Catalysis: Enantioselective Hydrogenation of Imines To Form Amines

(2011) Shaolin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Controlled Highly Regioselective and Asymmetric Hydrogenation of Quinoxalines Catalyzed by Ruthenium N-Heterocyclic Carbene Complexes

(2011) Slawomir Urban et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogenation of imino bonds with half-sandwich metal catalysts

(2011) Chao Wang et al.   CHEMICAL COMMUNICATIONS

Phosphine−Phosphinite and Phosphine−Phosphite Ligands: Preparation and Applications in Asymmetric Catalysis

(2011) Héctor Fernández-Pérez et al.   CHEMICAL REVIEWS

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

BINEPINES: chiral binaphthalene-core monophosphepine ligands for multipurpose asymmetric catalysis

(2011) Serafino Gladiali et al.   CHEMICAL SOCIETY REVIEWS

An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Brønsted Acid/Pd-Complex-Promoted Tandem Reactions

(2011) Ying Duan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones

(2011) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)

(2011) Neil A. Strotman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Hydrogenation of Quinolines Using Phosphine-Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism, and Origin of Enantioselectivity

(2011) Tianli Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Hydrogenation of N-Boc-Imidazoles and Oxazoles

(2011) Ryoichi Kuwano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Convergent Asymmetric Disproportionation Reactions: Metal/Brønsted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines

(2011) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Partial Hydrogenation of Simple Pyrroles: A Facile Access to Chiral 1-Pyrrolines

(2011) Duo-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical, Catalytic Enantioselective Hydrogenation to SynthesizeN-Unprotected β-Amino Esters

(2011) Kazuhiko Matsumura et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Synthesis of (S)-3-Amino-4-methoxy-butan-1-ol by Way of Reductive Amination

(2011) Patrizio Mattei et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Design of frustrated Lewis pair catalysts for metal-free and selective hydrogenation

(2011) Tibor Soós   PURE AND APPLIED CHEMISTRY

Enantioselective Synthesis of Quinolizidines and Indolizidines via a Catalytic Asymmetric Hydrogenation Cascade

(2011) Magnus Rueping et al.   SYNLETT

pH-Regulated transfer hydrogenation of quinoxalines with a Cp*Ir–diamine catalyst in aqueous media

(2011) Jing Tan et al.   TETRAHEDRON

Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles

(2011) Duo-Sheng Wang et al.   Chemical Science

Organocatalytic asymmetric transfer hydrogenation of imines

(2011) Johannes G. de Vries et al.   Catalysis Science & Technology

Diastereoselective Hydrogenation of Substituted Quinolines to Enantiomerically Pure Decahydroquinolines

(2010) Maja Heitbaum et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Enantioselective Hydrogenation of Quinoline and Pyridine Derivatives with Iridium-(P-Phos) Catalyst

(2010) Wei-Jun Tang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Reductive Amination of α-Branched Ketones

(2010) Vijay N. Wakchaure et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Catalyst for Reductive Amination by Transfer Hydrogenation

(2010) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Practical One-Pot Synthesis of Secondary Amines by Zinc-Catalyzed Reductive Amination

(2010) Stephan Enthaler   CATALYSIS LETTERS

Highlights of Transition Metal-Catalyzed Asymmetric Hydrogenation of Imines

(2010) Nicolas Fleury-Brégeot et al.   ChemCatChem

Brønsted acid differentiated metal catalysis by kinetic discrimination

(2010) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

Unifying Metal and Brønsted Acid Catalysis-Concepts, Mechanisms, and Classifications

(2010) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

The First General, Efficient and Highly Enantioselective Reduction of Quinoxalines and Quinoxalinones

(2010) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium-Catalyzed Asymmetric Hydrogenation of N-Protected Indoles

(2010) Alejandro Baeza et al.   CHEMISTRY-A EUROPEAN JOURNAL

Convenient Synthesis of Optically Pure 8-Methoxy-2-methyl-1,2,3,4-tetrahydroquinoline and 2-Methyl-1,2,3,4-tetrahydroquinoline

(2010) Yong-Gui Zhou et al.   HETEROCYCLES

Highly Efficient Iridium-Catalyzed Asymmetric Hydrogenation of Unprotected β-Enamine Esters

(2010) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium−Monodentate Phosphoramidite-Catalyzed Asymmetric Hydrogenation of Substituted Benzophenone N−H Imines

(2010) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Brønsted Acids

(2010) Duo-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of Phosphine-Phosphite Ligands in the Iridium Catalyzed Enantioselective Hydrogenation of 2-Methylquinoline

(2010) Miguel Rubio et al.   MOLECULES

Phosphine-free chiral metal catalysts for highly effective asymmetric catalytic hydrogenation

(2010) Yan-Mei He et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly efficient and enantioselective hydrogenation of quinolines and pyridines with Ir-Difluorphos catalyst

(2010) Weijun Tang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation ofortho-Hydroxyaryl Alkyl N−H Ketimines

(2010) Thanh Binh Nguyen et al.   ORGANIC LETTERS

Asymmetric Hydrogenation of Heteroaromatic Compounds Mediated by Iridium−(P-OP) Complexes

(2010) José L. Núñez-Rico et al.   ORGANOMETALLICS

Developing chiral phosphorus ligands for asymmetric hydrogenations

(2010) Wei Li et al.   PURE AND APPLIED CHEMISTRY

Thieme Chemistry Journal Awardees - Where Are They Now? Asymmetric Brønsted Acid Catalyzed Transfer Hydrogenations

(2010) Magnus Rueping et al.   SYNLETT

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Asymmetric hydrogenation of quinolines activated by Brønsted acids

(2010) Duo-Sheng Wang et al.   TETRAHEDRON LETTERS

Enantioselective hydrogenation of indoles derivatives catalyzed by Walphos/rhodium complexes

(2010) Anna M. Maj et al.   TETRAHEDRON-ASYMMETRY

Asymmetric hydrogenation of 2-substituted N-protected-indoles catalyzed by rhodium complexes of BINOL-derived phosphoramidites

(2010) Nataša Mršić et al.   TETRAHEDRON-ASYMMETRY

Asymmetric Brønsted acid catalysis in aqueous solution

(2010) Magnus Rueping et al.   Chemical Science

Highly Efficient and Versatile Phosphine-Phosphoramidite Ligands for Asymmetric Hydrogenation

(2009) Matthias Eggenstein et al.   ADVANCED SYNTHESIS & CATALYSIS

pH-Regulated Asymmetric Transfer Hydrogenation of Quinolines in Water

(2009) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Unprecedented Halide Dependence on Catalytic Asymmetric Hydrogenation of 2-Aryl- and 2-Alkyl-Substituted Quinolinium Salts by Using Ir Complexes with Difluorphos and Halide Ligands

(2009) Hiroshi Tadaoka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly enantioselective hydrogenation of quinolines under solvent-free or highly concentrated conditions

(2009) Zhi-Jian Wang et al.   GREEN CHEMISTRY

Catalytic Asymmetric Hydrogenation of 5-Membered Heteroaromatics

(2009) Ryoichi Kuwano   HETEROCYCLES

Enantioselective Hydrogenation of N−H Imines

(2009) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Asymmetric Synthesis of Sitagliptin

(2009) Karl B. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen-Bonding Asymmetric Metal Catalysis with α-Amino Acids: A Simple and Tunable Approach to High Enantioinduction

(2009) Yingdong Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Reductive Amination

(2009) Dietrich Steinhuebel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal−Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination

(2009) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzothiazoline: Highly Efficient Reducing Agent for the Enantioselective Organocatalytic Transfer Hydrogenation of Ketimines

(2009) Chen Zhu et al.   ORGANIC LETTERS

Remarkable Positive Effect of Silver Salts on Asymmetric Hydrogenation of Acyclic Imines with Cp*Ir Complexes Bearing Chiral N-Sulfonylated Diamine Ligands

(2009) Shin-yo Shirai et al.   ORGANOMETALLICS

Asymmetric Hydrogenation of Quinolines Catalyzed by Iridium Complexes of Monodentate BINOL-Derived Phosphoramidites

(2008) Nataša Mršić et al.   ADVANCED SYNTHESIS & CATALYSIS

Hydrogenation of Quinolines Using a Recyclable Phosphine-Free Chiral Cationic Ruthenium Catalyst: Enhancement of Catalyst Stability and Selectivity in an Ionic Liquid

(2008) Haifeng Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Broader, Greener, and More Efficient: Recent Advances in Asymmetric Transfer Hydrogenation

(2008) Chao Wang et al.   Chemistry-An Asian Journal

Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

(2008) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Theoretical Study of the Mechanism of Hantzsch Ester Hydrogenation of Imines Catalyzed by Chiral BINOL-Phosphoric Acids

(2008) Luis Simón et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Hydrogenation of Cyclic Imines with an Ionic Cp*Rh(III) Catalyst

(2008) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Air-Stable and Phosphine-Free Iridium Catalysts for Highly Enantioselective Hydrogenation of Quinoline Derivatives†

(2008) Zhi-Wei Li et al.   ORGANIC LETTERS

Iridium-catalyzed asymmetric hydrogenation of pyridine derivatives, 7,8-dihydro-quinolin-5(6H)-ones

(2008) Xiao-Bing Wang et al.   TETRAHEDRON LETTERS

Catalytic Asymmetric Hydrogenation of 2,3,5-Trisubstituted Pyrroles

(2007) Ryoichi Kuwano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY