The Catalytic Enantioselective Total Synthesis of (+)-Liphagal

PREPARATION OF (S)-2-ALLYL-2-METHYLCYCLOHEXANONE

(2014)   ORGANIC SYNTHESES

A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B

(2011) Herschel Mukherjee et al.   ORGANIC LETTERS

Synthesis of Phosphatidylinositol 3-Kinase (PI3K) Inhibitory Analogues of the Sponge Meroterpenoid Liphagal

(2010) Alban R. Pereira et al.   JOURNAL OF MEDICINAL CHEMISTRY

A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres

(2010) Jan Streuff et al.   Nature Chemistry

Enantioselective Total Synthesis of the Selective PI3 Kinase Inhibitor Liphagal

(2010) Enrique Alvarez-Manzaneda et al.   ORGANIC LETTERS

Enantiospecific, Biosynthetically Inspired Formal Total Synthesis of (+)-Liphagal

(2010) Jonathan H. George et al.   ORGANIC LETTERS

Efficient Synthesis of Key Intermediate Toward Liphagal Synthesis

(2010) Vijaykumar Deore et al.   SYNTHETIC COMMUNICATIONS

A general enantioselective route to the chamigrene natural product family

(2010) David E. White et al.   TETRAHEDRON

Synthetic and computational studies on liphagal: a natural product inhibitor of PI-3K

(2010) Yanzhong Zhang et al.   TETRAHEDRON LETTERS

Unusual Allylpalladium Carboxylate Complexes: Identification of the Resting State of Catalytic Enantioselective Decarboxylative Allylic Alkylation Reactions of Ketones

(2009) Nathaniel H. Sherden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of Enol Carbonates

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acids

(2009) Stephan J. Zuend et al.   NATURE

Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity

(2009) Teather J. Sundstrom et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Use of 5,5-(Dimethyl)-i-Pr-PHOX as a Practical Equivalent tot-Bu-PHOX in Asymmetric Catalysis

(2009) Étienne Bélanger et al.   ORGANIC LETTERS

A concise synthesis of the bioactive meroterpenoid natural product (±)-liphagal, a potent PI3K inhibitor

(2009) Goverdhan Mehta et al.   TETRAHEDRON LETTERS

Palladium-Catalyzed Diastereoselective and Enantioselective Allylic Alkylations of Ketone Enolates

(2008) Manfred Braun et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers: Ready Access to C(α)-Tetrasubstituted Hydroxyketones, Acids, and Esters

(2008) Masaki Seto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unexpected effect of the fluorine atom on the optimal ligand-to-palladium ratio in the enantioselective Pd-catalyzed allylation reaction of fluorinated enol carbonates

(2008) Étienne Bélanger et al.   CHEMICAL COMMUNICATIONS

The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation

(2008) John A. Enquist Jr et al.   NATURE

Enantioselective Total Synthesis of (+)-Cassiol

(2008) Krastina V. Petrova et al.   ORGANIC LETTERS

Catalytic Enantioselective Approach to the Eudesmane Sesquiterpenoids: Total Synthesis of (+)-Carissone

(2008) Samantha R. Levine et al.   ORGANIC LETTERS

Enamines: efficient nucleophiles for the palladium-catalyzed asymmetric allylic alkylation

(2008) Xiaohu Zhao et al.   TETRAHEDRON

The Catalytic Asymmetric Total Synthesis of Elatol

(2007) David E. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY