Shuttle-Mediated Drug Delivery to the Brain

Delivery of Neuropeptides from the Periphery to the Brain: Studies with Enkephalin

(2010) Yoram Shechter et al.   ACS Chemical Neuroscience

Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein Penetrates the Blood-Brain Barrier in the Mouse

(2010) Q.-H. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Enhanced efficacy of functionalized epirubicin liposomes in treating brain glioma-bearing rats

(2010) Wei Tian et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery

(2010) Huali Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein

(2010) Ruben J. Boado et al.   JOURNAL OF BIOTECHNOLOGY

N-Methyl Phenylalanine-Rich Peptides as Highly Versatile Blood−Brain Barrier Shuttles

(2010) Morteza Malakoutikhah et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Angiopep-Modified Doxorubicin (ANG1007) and Etoposide (ANG1009) Chemotherapeutics With Increased Brain Penetration

(2010) Christian Ché et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemical Delivery System of Metaiodobenzylguanidine (MIBG) to the Central Nervous System

(2010) Fabienne Gourand et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antiprotozoal Activity ofN-Alkoxy Analogues of the Trypanocidal Lead Compound 4,4′-Bis(imidazolinylamino)diphenylamine with Improved Human Blood−Brain Barrier Permeability

(2010) Lidia Nieto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain

(2010) H.-L. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-Brain Barrier Disruption with Focused Ultrasound Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment

(2010) Hao-Li Liu et al.   RADIOLOGY

Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain

(2009) Zhao H. Wang et al.   BIOMATERIALS

Chitosan solutions and particles: Evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model

(2009) Juliane Hombach et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones

(2009) Anja Zensi et al.   JOURNAL OF CONTROLLED RELEASE

Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals

(2009) Xue Ying et al.   JOURNAL OF CONTROLLED RELEASE

In vivo interactions of magnetic nanoparticles with the blood–brain barrier

(2009) Patricia Stepp et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Glucose Promoiety Enables Glucose Transporter Mediated Brain Uptake of Ketoprofen and Indomethacin Prodrugs in Rats

(2009) Mikko Gynther et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tumor Necrosis Factor Receptor-IgG Fusion Protein for Targeted Drug Delivery across the Human Blood−Brain Barrier

(2009) Eric Ka-Wai Hui et al.   MOLECULAR PHARMACEUTICS

Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood−Brain Barrier and Survival of Brain Tumor-Bearing Animals

(2009) Ju Du et al.   MOLECULAR PHARMACEUTICS

Pharmacokinetics and Brain Uptake of a Genetically Engineered Bifunctional Fusion Antibody Targeting the Mouse Transferrin Receptor

(2009) Ruben J. Boado et al.   MOLECULAR PHARMACEUTICS

Nanoparticles as drug delivery agents specific for CNS: in vivo biodistribution

(2009) Anna Valeria Vergoni et al.   Nanomedicine-Nanotechnology Biology and Medicine

Synthesis, radiosynthesis and biological evaluation of 1,4-dihydroquinoline derivatives as new carriers for specific brain delivery

(2009) Lénaïg Foucout et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer

(2009) Fancy C. Thomas et al.   PHARMACEUTICAL RESEARCH

Quantum Dots Bearing Lectin-Functionalized Nanoparticles as a Platform forIn VivoBrain Imaging

(2008) Xiaoling Gao et al.   BIOCONJUGATE CHEMISTRY

Bioconjugated Quantum Rods as Targeted Probes for Efficient Transmigration Across an in Vitro Blood−Brain Barrier

(2008) Gaixia Xu et al.   BIOCONJUGATE CHEMISTRY

TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs

(2008) Kavitha S. Rao et al.   BIOMATERIALS

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse

(2008) Ruben J. Boado et al.   BIOTECHNOLOGY AND BIOENGINEERING

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

(2008) Barnabas Wilson et al.   BRAIN RESEARCH

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2

(2008) A Régina et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeted delivery of tacrine into the brain with polysorbate 80-coated poly(n-butylcyanoacrylate) nanoparticles

(2008) B WILSON et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)

(2008) Karsten Ulbrich et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes

(2008) Eyal Afergan et al.   JOURNAL OF CONTROLLED RELEASE

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26

(2008) Zhiqing Pang et al.   JOURNAL OF CONTROLLED RELEASE

Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations

(2008) Kaili Hu et al.   JOURNAL OF CONTROLLED RELEASE

Design, Synthesis and Biological Evaluation of Glutathione Peptidomimetics as Components of Anti-Parkinson Prodrugs

(2008) Swati S. More et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toward an Optimal Blood−Brain Barrier Shuttle by Synthesis and Evaluation of Peptide Libraries

(2008) Morteza Malakoutikhah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs

(2008) Mikko Gynther et al.   JOURNAL OF MEDICINAL CHEMISTRY

Significant delivery of tacrine into the brain using magnetic chitosan microparticles for treating Alzheimer's disease

(2008) Barnabas Wilson et al.   JOURNAL OF NEUROSCIENCE METHODS

The toxicity of β-amyloid is attenuated by interaction with its specific human scFv E3 in vitro

(2008) Shen Yue et al.   LIFE SCIENCES

Methotrexate Loaded Polyether-Copolyester Dendrimers for the Treatment of Gliomas: Enhanced Efficacy and Intratumoral Transport Capability

(2008) Renu Singh Dhanikula et al.   MOLECULAR PHARMACEUTICS

Targeting β-amyloid pathology in Alzheimer’s disease with Aβ immunotherapy

(2008) Roger M. Nitsch et al.   Neurotherapeutics

Brain targeting using novel lipid nanovectors

(2007) Arnaud Béduneau et al.   JOURNAL OF CONTROLLED RELEASE