Article
Chemistry, Organic
Takayuki Kanagawa, Shigetoshi Tachibana, Yoshiaki Masaki, Kohji Seio
Summary: A cyclic nucleoside has been designed and synthesized to introduce specific conformations into functional nucleic acids by fixing the rotation, base orientation, and sugar structure.
Article
Chemistry, Inorganic & Nuclear
Dameng Sun, Xin Huang, Ruojun Man, Xinjie Jia, Xinluan Song, Sihan Wang, Xingyong Xue, Hongming Liu, Zhen Ma
Summary: A series of Fe(ii) complexes were synthesized using modified terpyridine ligands, and they exhibited high antiproliferation activities against human cancer cell lines with low toxicity to normal cells. The carboxyl-modified complex showed significant selectivity in killing hepatoma cancer cells. These Fe(ii) complexes have potential as anticancer drugs against hepatoma cancer.
DALTON TRANSACTIONS
(2023)
Article
Physics, Multidisciplinary
Dongsheng Song, Rafal E. Dunin-Borkowski
Summary: This study presents a method for three-dimensional magnetic measurement at atomic scale using EMCD technology, which allows for obtaining signals related to magnetization in three Cartesian directions by using a subangstrom convergent electron beam in STEM. Atomic resolution EMCD signals from all three directions can be separately acquired by moving the detector, and signal enhancement can be achieved by using a defocused electron beam.
PHYSICAL REVIEW LETTERS
(2021)
Article
Optics
Joohoon Kim, Wonjoong Kim, Dong Kyo Oh, Hyunjung Kang, Hongyoon Kim, Trevon Badloe, Seokwoo Kim, Chanwoong Park, Hojung Choi, Heon Lee, Junsuk Rho
Summary: This paper introduces a single-step printable platform for UV metasurfaces, which solves the problems of scarcity in low-loss UV materials and manufacturing limitations of high cost and low throughput. A UV-curable resin dispersed with zirconium dioxide (ZrO2) nanoparticles is developed as a printable material, which has a high refractive index and low extinction coefficient in the UV range. By utilizing nanoimprint lithography, UV metasurfaces can be fabricated in a single step. Experimental results demonstrate the feasibility of this method in fabricating UV metaholograms with vivid and clear holographic images. The proposed method enables repeat and rapid manufacturing of UV metasurfaces, bringing them closer to real-life applications.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Physics, Applied
Tomohiro Yasuda, Kenta Amemiya, Takashi Suemasu
Summary: In this study, we successfully fabricated ultrathin Mn4N films with a thickness of around 4 nm and discovered a reversed sign of the anomalous Hall resistivity as the film thickness decreased. X-ray magnetic circular dichroism measurements revealed that the magnetic structure of Mn4N with a thickness of around 4 nm is different from that of conventional ferrimagnetic Mn4N films. These findings are of great importance for studying spin-orbit torque and interfacial Dzyaloshinskii-Moriya interaction in Mn4N ultrathin films.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Chong-Yang Li, Han Xu, Pei-Ming Cheng, Ming-Hao Du, La-Sheng Long, Lan-Sun Zheng, Xiang-Jian Kong
Summary: This study presents the mechanism behind the formation of chiral crystals and explores their chiral expression from micro- to macroscopic levels. The research also reveals the strong magneto-optical response of chiral crystals, highlighting their potential as magneto-optical materials.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Biochemical Research Methods
Masanobu Nagano, Sosuke Nakano, Keitaro Yoshimoto
Summary: This study presents a method for identifying deoxyguanines (dGs) that form antiparallel G4 using optical spectroscopy, called dG-to-dT scanning. By comparing the spectra at all dG positions, the most strongly involved dGs in forming antiparallel G4 can be determined. This method provides a simple and robust approach for understanding the formation of de novo antiparallel G4.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Gayane Ananyan, Nelli H. Karapetyan, Yeva B. Dalyan
Summary: The binding characteristics of water-soluble porphyrins and their Cu and Co derivatives with synthetic polynucleotides were studied, showing different binding modes at different concentrations. The calculated binding constants and exclusion parameters for each complex aligned well with proposed models.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Chemistry, Inorganic & Nuclear
Zhaohui Zong, Heng Zhang, Aiyou Hao, Pengyao Xing
Summary: This study reveals that intramolecular chirality transfer behaviors in ferrocene-conjugated amino acids depend on the substituent groups, influencing multiple intramolecular interactions and molecular geometry. The research also demonstrates that intramolecular weak forces have an impact on molecular geometry and contribute to diverse Cotton effects. This work provides evidence for the ignored intramolecular factors in self-assembled systems and paves the way for the fabrication of functional chiroptical systems.
DALTON TRANSACTIONS
(2021)
Article
Materials Science, Multidisciplinary
Herman Duim, Maria Antonietta Loi
Summary: This article discusses the potential of chiral hybrid organic-inorganic metal halides (HMHs) in the field of optics, examining the impact of chiral transfer on electronic structure and optical properties. It further explores efforts to improve and tune the chiroptical response, while also proposing future research directions for enhancing chiral HMHs.
Article
Chemistry, Multidisciplinary
Qi Zhang, Stefano Crespi, Ryojun Toyoda, Romain Costil, Wesley R. Browne, Da-Hui Qu, He Tian, Ben L. Feringa
Summary: By utilizing hydrogen bonds, control over the chirality of disulfide bonds is achieved to enable intramolecular and supramolecular chirality transfers, showcasing the accessibility of dynamic stereochemical space through noncovalent chirality transmission encoded in homochiral amino acid building blocks.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Qi-Ping Hu, Hao Zhou, Teng-Yu Huang, Yu-Fei Ao, De-Xian Wang, Qi-Qiang Wang
Summary: An adaptive, achiral trithiourea molecular cage and its conformational and stereodynamics toward tricarboxylate anion binding are reported. The cage exhibits a flexible conformation and strongly binds 1,3,5-benzene tricarboxylate, forming a sandwich-like inclusion complex. By incorporating chiral arms on the guest, a gear-like complex with a specific helical sense is produced.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Materials Science, Multidisciplinary
Takamasa Hirai, Kento Hasegawa, Shinya Ota, Motohiro Suzuki, Tomohiro Koyama, Daichi Chiba
Summary: In Co/Pt/oxide systems, fieldlike SOT is significantly influenced by the adjacent oxide material, while dampinglike SOT is almost irrelevant to oxides. The efficiency of FL SOT in the Pt/HfO2 sample is 2.2 times greater than that in the Pt/MgO sample at the maximum. X-ray magnetic circular dichroism spectroscopy suggests that the modulation of the electronic structure at the Pt/oxide interface contributes to SOT enhancement.
Article
Medicine, Research & Experimental
Farkhad Maksudov, Evgenii Kliuchnikov, Daniel Pierson, M. L. Ujwal, Kenneth A. Marx, Arani Chanda, Valeri Barsegov
Summary: This article investigates the structure-function relationships of PMOs, which are therapeutic RNA mimicking molecules. By utilizing various techniques, such as circular dichroism and molecular dynamics simulations, the solution structures of PMOs were determined. The study reveals that PMOs adopt non-canonical, partially helical, and stable folded structures, and exhibit thermodynamic stability and concentration-dependent viscosity properties.
MOLECULAR THERAPY-NUCLEIC ACIDS
(2023)
Article
Chemistry, Multidisciplinary
Li Ma, Yan Liu, Cong Han, Artur Movsesyan, Peihang Li, Huacheng Li, Pan Tang, Yongqing Yuan, Shuoxing Jiang, Weihai Ni, Hao Yan, Alexander O. Govorov, Zhiming M. Wang, Xiang Lan, Li Ma
Summary: Quasi-planar chiral satellite-core nanoparticle superstructures were created using DNA origami technology. Through comprehensive theoretical studies and experimental measurements, the chiral mechanisms were explained and different optical responses were demonstrated.
