Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research

Modeling human diseases in Caenorhabditis elegans

(2010) Maria Markaki et al.   Biotechnology Journal

High-throughput screening and small animal models, where are we?

(2010) Jean Giacomotto et al.   BRITISH JOURNAL OF PHARMACOLOGY

C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes

(2010) Shahid S. Siddiqui et al.   CANCER BIOLOGY & THERAPY

The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility

(2010) Lillian K. Fritz-Laylin et al.   CELL

Drosophila Genetic Resource and Stock Center; The National BioResource Project

(2010) Masa-Toshi YAMAMOTO   EXPERIMENTAL ANIMALS

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Erratum: Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

(2010) Luke H. Stockwin et al.   INTERNATIONAL JOURNAL OF CANCER

High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics

(2010) Jeffrey N. Stirman et al.   JOURNAL OF NEUROSCIENCE METHODS

The Longevity Effect of Tannic Acid in Caenorhabditis elegans: Disposable Soma Meets Hormesis

(2010) Nadine Saul et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies

(2010) Jan Krajniak et al.   LAB ON A CHIP

Getting in the Loop: Regulation of Development in Caulobacter crescentus

(2010) P. D. Curtis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

(2010) Andrew R Burns et al.   Nature Chemical Biology

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

(2010) C. Kenyon   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Alpha-Synuclein Disrupted Dopamine Homeostasis Leads to Dopaminergic Neuron Degeneration in Caenorhabditis elegans

(2010) Pengxiu Cao et al.   PLoS One

In VivoImaging ofCaenorhabditis elegansGlycans

(2009) Scott T. Laughlin et al.   ACS Chemical Biology

A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans

(2009) Hui Ma et al.   Biomicrofluidics

The lifespan-promoting effect of acetic acid and Reishi polysaccharide

(2009) Ming-Hong Chuang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Advanced in silico analysis of expressed sequence tag (EST) data for parasitic nematodes of major socio-economic importance — Fundamental insights toward biotechnological outcomes

(2009) Shoba Ranganathan et al.   BIOTECHNOLOGY ADVANCES

Understanding the molecular basis of Alzheimer’s disease using a Caenorhabditis elegans model system

(2009) Collin Y. Ewald et al.   Brain Structure & Function

Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression

(2009) Seung-Jae Lee et al.   Cell Metabolism

In vitro organogenesis from undifferentiated cells inXenopus

(2009) Makoto Asashima et al.   DEVELOPMENTAL DYNAMICS

C. elegans as Model for the Study of High Glucose- Mediated Life Span Reduction

(2009) A. Schlotterer et al.   DIABETES

Metabolic Profiling Strategy ofCaenorhabditis elegansby Whole-Organism Nuclear Magnetic Resonance

(2009) Benjamin J. Blaise et al.   JOURNAL OF PROTEOME RESEARCH

Worms from Venus and Mars: Proteomics Profiling of Sexual Differences inCaenorhabditis elegansUsingin Vivo15N Isotope Labeling

(2009) Bastiaan B. J. Tops et al.   JOURNAL OF PROTEOME RESEARCH

A Photocontrolled Molecular Switch Regulates Paralysis in a Living Organism

(2009) Usama Al-Atar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Is There a Role for New Invertebrate Models for Aging Research?

(2009) S. N. Austad   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Automated high-throughput cell microsurgery on-chip

(2009) Kwanghun Chung et al.   LAB ON A CHIP

SU-8 force sensing pillar arrays for biological measurements

(2009) Joseph C. Doll et al.   LAB ON A CHIP

Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans

(2009) S. Elizabeth Hulme et al.   LAB ON A CHIP

Electrotaxis of Caenorhabditis elegans in a microfluidic environment

(2009) Pouya Rezai et al.   LAB ON A CHIP

Dictyostelium discoideum—a model for many reasons

(2009) Sarah J. Annesley et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidation of a potassium channel causes progressive sensory function loss during aging

(2009) Shi-Qing Cai et al.   NATURE NEUROSCIENCE

The quest for action potentials in C. elegans neurons hits a plateau

(2009) Shawn R Lockery et al.   NATURE NEUROSCIENCE

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases

(2009) Manuel Zimmer et al.   NEURON

Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans

(2009) C. Morck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two size-selective mechanisms specifically trap bacteria-sized food particles in Caenorhabditis elegans

(2009) C. Fang-Yen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of mitochondria fromCaenorhabditis elegans

(2009) Jing Li et al.   PROTEOMICS

Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?

(2009) Federico Sesti et al.   TRENDS IN CELL BIOLOGY

Fat synthesis and adiposity regulation in Caenorhabditis elegans

(2009) Jennifer L. Watts   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Signals of youth: endocrine regulation of aging in Caenorhabditis elegans

(2009) Siler H. Panowski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

How to become a parasite – lessons from the genomes of nematodes

(2009) Christoph Dieterich et al.   TRENDS IN GENETICS

Helminth Genomics: The Implications for Human Health

(2009) Paul J. Brindley et al.   PLoS Neglected Tropical Diseases

Mass spectrometric proteome analysis suggests anaerobic shift in metabolism of Dauer larvae of Caenorhabditis elegans

(2008) András Mádi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Dietary regulation of hypodermal polyploidization in C. elegans

(2008) Luke S Tain et al.   BMC DEVELOPMENTAL BIOLOGY

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Compounds that confer thermal stress resistance and extended lifespan

(2008) Michael G. Benedetti et al.   EXPERIMENTAL GERONTOLOGY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

Olfactory Behavior of Swimming C. elegans Analyzed by Measuring Motile Responses to Temporal Variations of Odorants

(2008) Linjiao Luo et al.   JOURNAL OF NEUROPHYSIOLOGY

Artificial Dirt: Microfluidic Substrates for Nematode Neurobiology and Behavior

(2008) S. R. Lockery et al.   JOURNAL OF NEUROPHYSIOLOGY

Single-synapse ablation and long-term imaging in live C. elegans

(2008) Peter B. Allen et al.   JOURNAL OF NEUROSCIENCE METHODS

Droplet-based microfluidic system for individual Caenorhabditis elegans assay

(2008) Weiwei Shi et al.   LAB ON A CHIP

Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation

(2008) Fei Zeng et al.   LAB ON A CHIP

CO2and compressive immobilization of C. elegans on-chip

(2008) Trushal Vijaykumar Chokshi et al.   LAB ON A CHIP

Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system

(2008) Matthew M. Crane et al.   LAB ON A CHIP

The chicken embryo as a model for developmental endocrinology: Development of the thyrotropic, corticotropic, and somatotropic axes

(2008) B. De Groef et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A new class of anthelmintics effective against drug-resistant nematodes

(2008) Ronald Kaminsky et al.   NATURE

Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies

(2008) Samuel X Guo et al.   NATURE METHODS

Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans

(2008) Kwanghun Chung et al.   NATURE METHODS

Light-sensitive neurons and channels mediate phototaxis in C. elegans

(2008) Alex Ward et al.   NATURE NEUROSCIENCE

Action potentials contribute to neuronal signaling in C. elegans

(2008) Jerry E Mellem et al.   NATURE NEUROSCIENCE

Trace administration of vitamin E can retrieve and prevent UV-irradiation- and metal exposure-induced memory deficits in nematode Caenorhabditis elegans

(2008) Huayue Ye et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The genome of Brugia malayi — All worms are not created equal

(2008) Alan L. Scott et al.   PARASITOLOGY INTERNATIONAL

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

The Parallel Worm Tracker: A Platform for Measuring Average Speed and Drug-Induced Paralysis in Nematodes

(2008) Daniel Ramot et al.   PLoS One

Enhanced Caenorhabditis elegans Locomotion in a Structured Microfluidic Environment

(2008) Sungsu Park et al.   PLoS One

Hypoxia and the HIF-1 transcriptional pathway reorganize a neuronal circuit for oxygen-dependent behavior in Caenorhabditis elegans

(2008) A. J. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components

(2008) R. A. Butcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging

(2008) X. Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE

Glia Are Essential for Sensory Organ Function in C. elegans

(2008) T. Bacaj et al.   SCIENCE

Caenorhabditis elegans nuclear receptors: insights into life traits

(2008) Daniel B. Magner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolic activation of PCBs to carcinogens in vivo—A review

(2007) Gabriele Ludewig et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY