Article
Nutrition & Dietetics
Caitriona McGovern, Sheryl L. Rifas-Shiman, Karen M. Switkowski, Jennifer A. Woo Baidal, Jenifer R. Lightdale, Marie-France Hivert, Emily Oken, Izzuddin M. Aris
Summary: Consuming higher-fat milk in early childhood is not associated with increased adiposity or adverse cardiometabolic health in early adolescence.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Ahmed Elhakeem, Amy E. Taylor, Hazel M. Inskip, Jonathan Huang, Muriel Tafflet, Johan L. Vinther, Federica Asta, Jan S. Erkamp, Luigi Gagliardi, Kathrin Guerlich, Jane Halliday, Margreet W. Harskamp-van Ginkel, Jian-Rong He, Vincent W. V. Jaddoe, Sharon Lewis, Gillian M. Maher, Yannis Manios, Toby Mansell, Fergus P. McCarthy, Sheila W. McDonald, Emanuela Medda, Lorenza Nistico, Angela Pinot de Moira, Maja Popovic, Irwin K. M. Reiss, Carina Rodrigues, Theodosia Salika, Ash Smith, Maria A. Stazi, Caroline Walker, Muci Wu, Bjorn O. Asvold, Henrique Barros, Sonia Brescianini, David Burgner, Jerry K. Y. Chan, Marie-Aline Charles, Johan G. Eriksson, Romy Gaillard, Veit Grote, Siri E. Haberg, Barbara Heude, Berthold Koletzko, Susan Morton, George Moschonis, Deirdre Murray, Desmond O'Mahony, Daniela Porta, Xiu Qiu, Lorenzo Richiardi, Franca Rusconi, Richard Saffery, Suzanne C. Tough, Tanja G. M. Vrijkotte, Scott M. Nelson, Anne-Marie Nybo Andersen, Maria C. Magnus, Deborah A. Lawlor
Summary: This study found that offspring conceived via assisted reproductive technology (ART) were shorter, lighter, and thinner than those conceived naturally during infancy to early adolescence. However, these differences diminished with older child age and were no longer evident in late adolescence. Hence, individuals conceived or conceiving through ART can be reassured that early growth and adiposity differences are small and temporary.
Article
Cardiac & Cardiovascular Systems
Juliana Nyasordzi, Johanna Conrad, Janina Goletzke, Helena Ludwig-Walz, Christian Herder, Michael Roden, Stefan A. Wudy, Yifan Hua, Thomas Remer, Anette E. Buyken
Summary: The study found that early life factors such as early pregnancy BMI, gestational weight gain, and full breastfeeding are associated with markers of cardiometabolic risk in offspring, which may be mediated by body composition in young adulthood.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Review
Peripheral Vascular Disease
Empar Lurbe, Julie Ingelfinger
Summary: This review critically considers the association between birth weight, growth trajectories, and cardiometabolic disease, highlighting the importance of early life interventions in reducing disease burden and improving public health outcomes.
Review
Nutrition & Dietetics
Dorota Drozdz, Julio Alvarez-Pitti, Malgorzata Wojcik, Claudio Borghi, Rosita Gabbianelli, Artur Mazur, Vesna Herceg-Cavrak, Beatriz Gonzalez Lopez-Valcarcel, Michal Brzezinski, Empar Lurbe, Elke Wuehl
Summary: Obesity is a major epidemic in the 21st century that increases the risk of various cardiometabolic factors. Early recognition of CV damage and prevention strategies are crucial in reducing CV morbidity and mortality. Recognizing and tracking risk factors from prenatal age to adulthood is essential in addressing the impact of obesity on cardiovascular health.
Article
Pediatrics
Rita Santos-Silva, Manuel Fontoura, Joao T. Guimaraes, Henrique Barros, Ana Cristina Santos
Summary: The study found that there is an association between low birth size and obesity with higher levels of dehydroepiandrosterone sulfate (DHEAS) in childhood. DHEAS levels were positively associated with all adiposity indicators.
PEDIATRIC RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Maria Joao Fonseca, Carla Moreira, Ana Cristina Santos
Summary: The study found that the earlier the adiposity rebound in childhood, the worse the cardiometabolic health in late childhood, as evidenced by higher levels of various indicators such as BMI, waist circumference, blood pressure, and insulin.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Hematology
Tom Norris, Liina Mansukoski, Mark S. Gilthorpe, Mark Hamer, Rebecca Hardy, Laura D. Howe, Alun D. Hughes, Leah Li, Emma O'Donnell, Ken K. Ong, George B. Ploubidis, Richard J. Silverwood, Russell M. Viner, William Johnson
Summary: This study aimed to identify different classes of individuals with similar BMI trajectories and study their associations with cardiometabolic health. Results showed that individuals with high and stable BMI across childhood may have lower cardiometabolic disease risk than individuals who become overweight or obese later in adolescence.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Article
Medicine, General & Internal
Yi-Han Hu, Michael R. Halstead, R. Nick Bryan, Pamela J. Schreiner, David R. Jacobs, Stephen Sidney, Cora E. Lewis, Lenore J. Launer
Summary: This study aims to investigate the association between blood pressure trajectory patterns from young adulthood to midlife and brain structure in midlife, and found that changes in blood pressure are associated with brain structural damage.
Article
Cardiac & Cardiovascular Systems
Linda M. O'Keeffe, Kate Tilling, Joshua A. Bell, Patrick T. Walsh, Matthew A. Lee, Deborah A. Lawlor, George Davey Smith, Patricia M. Kearney
Summary: This study quantified sex-specific trajectories of 148 metabolic traits from age 7 years to 25 years and found that females had higher VLDL particle concentrations at 7 years but decreased by 25 years, while males showed little change. Additionally, females had lower HDL particle concentrations at 7 years but increased by 25 years, while males showed no significant change.
Article
Psychology, Multidisciplinary
Shruti Garg, Ming Wai Wan, Jannath Begum-Ali, Anna Kolesnik-Taylor, Jonathan Green, Mark H. Johnson, Emily Jones, EDEN-STAARS Team
Summary: This study examines the trajectories of cognitive, motor, and behavioral development in infants with NF1. The results showed no significant group differences in cognitive and behavioral measures, but the NF1 group had less sleep and took longer to settle to sleep compared to the control group. Maternal education was associated with developmental outcomes in both groups.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Endocrinology & Metabolism
Sara E. Stinson, Anna E. Jonsson, Ierai Fernandez de Retana Alzola, Morten A. Lund, Christine Frithioff-Bojsoe, Louise Aas Holm, Cilius E. Fonvig, Oluf Pedersen, Lars Angquist, Thorkild I. A. Sorensen, Jens J. Holst, Michael Christiansen, Jens-Christian Holm, Bolette Hartmann, Torben Hansen
Summary: Elevated fasting glucagon concentrations in youth with overweight/obesity are associated with worsened cardiometabolic risk outcomes, except for hyperglycemia.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Geeta Appannah, Kevin Murray, Gina Trapp, Michael Dymock, Wendy Hazel Oddy, Gina Leslie Ambrosini
Summary: The study found that poor dietary patterns established in adolescence are likely to track into early adulthood, particularly in males. Factors such as maternal education, family income, and family functioning can influence dietary patterns.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Medicine, General & Internal
Marie C. Navarro, Isabelle Ouellet-Morin, Marie-Claude Geoffroy, Michel Boivin, Richard E. Tremblay, Sylvana M. Cote, Massimiliano Orri
Summary: Although early life factors modestly contribute to the prediction of suicidal behavior, their utility in predicting suicide attempts in adolescents and young adults is limited.
Article
Psychiatry
Amber John, Roopal Desai, Marcus Richards, Darya Gaysina, Joshua Stott
Summary: This study examined the associations between affective symptoms, cardiometabolic risk, and mid-life cognition through path models, revealing significant indirect associations between affective symptoms and mid-life cognitive function through cardiometabolic risk. The findings suggest the importance of cardiometabolic risk in understanding the relationship between affective symptoms and cognitive aging.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Nutrition & Dietetics
Claudia Ribeiro, Milton Severo, Andreia Oliveira, Henrique Barros, Elisabete Ramos
Summary: This study based on twins explores the influences of genetics, shared environment, and individual characteristics on changes in problematic eating behaviors from 4 to 7 years old. The findings suggest that shared environment plays a major role in these changes, with genetic characteristics becoming less relevant over time.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Health Care Sciences & Services
Sung Wook Kim, Lazaros Andronis, Anna-Veera Seppanen, Adrien M. Aubert, Henrique Barros, Elizabeth S. Draper, Mariane Sentenac, Jennifer Zeitlin, Stavros Petrou
Summary: This study aims to describe the health-related quality of life outcomes of children born very preterm and extremely preterm at five years of age, and explores the mediation effects of bronchopulmonary dysplasia and severe non-respiratory neonatal morbidity on those outcomes. The results suggest that extremely preterm birth and complications such as bronchopulmonary dysplasia and severe non-respiratory morbidity significantly impair health-related quality of life.
QUALITY OF LIFE RESEARCH
(2023)
Article
Anthropology
Mariane Helen de Oliveira, Joana Araujo, Elisabete Ramos, Wolney Lisboa Conde
Summary: This study aimed to develop new height references (MULT) based on multi-ethnic populations and compared them to the references from the Dutch Growth Study, CDC, and WHO. The MULT references were developed using longitudinal data from various studies. They showed a taller population compared to CDC and WHO references, especially for children under 5 years old. There was a high agreement between MULT and WHO references for subjects aged 2 to 5 years.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2023)
Article
Medicine, General & Internal
Rossella Alfano, Daniela Zugna, Henrique Barros, Mariona Bustamante, Leda Chatzi, Akram Ghantous, Zdenko Herceg, Pekka Keski-Rahkonen, Theo M. de Kok, Tim S. Nawrot, Caroline L. Relton, Oliver Robinson, Theano Roumeliotaki, Augustin Scalbert, Martine Vrijheid, Paolo Vineis, Lorenzo Richiardi, Michelle Plusquin
Summary: This meta-analysis explored the association between cord blood DNA methylation and rapid weight growth in six European child cohorts. The results identified 47 CpG sites and 16 genomic regions that were associated with rapid weight growth. Further analysis revealed that DNA methylation partially mediated the effect of gestational age on rapid weight growth, and was also associated with childhood overweight and prenatal exposures. These findings provide potential opportunities for early prevention and intervention of childhood obesity.
Review
Clinical Neurology
Rachel Valois, Catarina Tojal, Jose de Barros, Raquel Costa
Summary: This study analyzed and compared the language, memory, and learning outcomes of extremely preterm and very preterm children. It found that lower maternal age and education increased the risk of poor language performance, while lower maternal education and gestational age increased the likelihood of poor memory performance. Children living in disadvantaged social contexts were also at a higher risk of suboptimal cognitive development.
CHILD NEUROPSYCHOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmed Elhakeem, Amy E. Taylor, Hazel M. Inskip, Jonathan Y. Huang, Toby Mansell, Carina Rodrigues, Federica Asta, Sophia M. Blaauwendraad, Siri E. Haberg, Jane Halliday, Margreet W. Harskamp-van Ginkel, Jian-Rong He, Vincent W. V. Jaddoe, Sharon Lewis, Gillian M. Maher, Yannis Manios, Fergus P. McCarthy, Irwin K. M. Reiss, Franca Rusconi, Theodosia Salika, Muriel Tafflet, Xiu Qiu, Bjorn O. Asvold, David Burgner, Jerry K. Y. Chan, Luigi Gagliardi, Romy Gaillard, Barbara Heude, Maria C. Magnus, George Moschonis, Deirdre Murray, Scott M. Nelson, Daniela Porta, Richard Saffery, Henrique Barros, Johan G. Eriksson, Tanja G. M. Vrijkotte, Deborah A. Lawlor
Summary: This study aimed to examine the associations of assisted reproductive technology (ART) conception with offspring cardiometabolic health outcomes and whether these associations differ with age. The researchers found small and statistically non-significant differences in offspring cardiometabolic outcomes between ART-conceived and naturally conceived offspring. The study concluded that these findings should reassure individuals receiving ART, but longer-term follow-up is needed to investigate changes in the risks of hypertension, dyslipidaemia, and cardiovascular disease over adulthood.
EUROPEAN HEART JOURNAL
(2023)
Article
Nutrition & Dietetics
Joana Pinto Costa, Vania Magalhaes, Joana Araujo, Elisabete Ramos
Summary: A study on a population-based cohort found that a dietary pattern characterized by lower energy intake is associated with improved cardiometabolic health in adolescents. However, this effect was not significant in young adulthood.
NUTRITION RESEARCH
(2023)
Article
Pediatrics
Isaac Barroso, Elisabete Ramos, Vanda Craveiro, Jao Tiago Guimaraes
Summary: This study examined the relationship between leukocytes and social and environmental determinants of health in adolescents. The results showed that adolescents with better socioeconomic conditions and those who participated in sports had lower levels of white blood cells, while those with chronic diseases or allergies had higher levels of white blood cells. In addition, an increase in body mass index and systemic inflammation was associated with higher levels of white blood cells.
ARCHIVES DE PEDIATRIE
(2023)
Article
Sport Sciences
Ivone Carneiro, Peter Krustrup, Carlo Castagna, Magni Mohr, Jose Magalhaes, Rita Pereira, Rute Santos, Sandra Martins, Joao Tiago Guimaraes, Eduardo Coelho, Susana Povoas
Summary: This study aimed to examine the dose-response of a recreational team handball exercise-based programme on cardiometabolic health and physical fitness in inactive middle-aged-to-elderly males without TH experience. The results showed that performing three 60-minute team handball exercise sessions per week can improve aerobic performance in middle-aged-to-elderly men, and it is more effective than training with a lower weekly frequency.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Sport Sciences
Rita Pereira, Peter Krustrup, Carlo Castagna, Eduardo Coelho, Eva Wulff Helge, Niklas Rye Jorgensen, Carolina Vila-Cha, Sandra Martins, Joao Tiago Guimaraes, Jose Magalhaes, Susana Povoas
Summary: A multicomponent exercise training protocol (recreational team handball training) has long-term positive effects on global health status in inactive postmenopausal women. After 36 weeks of training, participants in the exercise group showed improvements in cardiovascular, bone, metabolic health, body composition, and physical fitness markers.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Marta Figueira, Ana Cristina Santos, Maria Joao Gregorio, Joana Araujo
Summary: Research found that from ages 4 to 7, 31.5% of children decreased screen time, 21.8% increased, 16.5% maintained low screen time, and 30.2% maintained high screen time. Children who increased screen exposure were more frequently from lower socioeconomic strata and presented unhealthier dietary patterns.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Endocrinology & Metabolism
Cathal McCrory, Sinead McLoughlin, Richard Layte, Cliona NiCheallaigh, Aisling M. O'Halloran, Henrique Barros, Lisa F. Berkman, Murielle Bochud, Eileen M. Crimmins, Meagan T. Farrell, Silvia Fraga, Emily Grundy, Michelle Kelly-Irving, Dusan Petrovic, Teresa Seeman, Silvia Stringhini, Peter Vollenveider, Rose Anne Kenny
Summary: This study analyzed data from 67,126 individuals aged 40-111 years participating in 13 different cohort studies and found that a 5-item measure of allostatic load (AL) can predict mortality as well as more elaborate sets of biomarkers.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Allergy
Mariana Farraia, Francisca Castro Mendes, Oksana Sokhatska, Milton Severo, Joao Cavaleiro Rufo, Henrique Barros, Andre Moreira
Summary: This study used data from a Portuguese birth cohort to identify trajectories of allergic sensitization profiles during childhood and evaluate their association with allergic outcomes. Five different trajectories were proposed, and their associations with asthma, rhinitis, and atopic dermatitis were analyzed.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Health Care Sciences & Services
Marta Goncalves, Ana Rute Costa, Milton Severo, Ana Henriques, Henrique Barros
Summary: The study aimed to describe sleep-wake patterns in young children and assess the association between sleep characteristics in early infancy and preschool ages. Two sleep patterns were identified, with pattern 1 characterized by earlier bedtime and wake-up times, and pattern 2 defined by later times. Factors such as maternal partnership change, kindergarten attendance, and having siblings influenced the frequency of pattern 2. The study highlights the importance of promoting proper sleep hygiene from infancy to ensure optimal sleep quality throughout life.
Article
Public, Environmental & Occupational Health
Anna-Veera Seppanen, Henrique Barros, Elizabeth S. Draper, Stavros Petrou, Lazaros Andronis, Sungwook Kim, Rolf F. Maier, Pernille Pedersen, Janusz Gadzinowski, Veronique Pierrat, Iemke Sarrechia, Jo Lebeer, Ulrika Aden, Liis Toome, Nicole Thiele, Arno van Heijst, Marina Cuttini, Jennifer Zeitlin
Summary: This study investigated the characteristics of follow-up policy and programmes for children born very preterm in 11 European countries from 2011 to 2022. The study found that there are significant variations in follow-up policies and programmes among European countries, and differences in recommended duration result in cross-country disparities in reported follow-up at 5 years of age.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2023)