Large adipocytes function as antigen-presenting cells to activate CD4+ T cells via upregulating MHCII in obesity

Metabolically normal obese people are protected from adverse effects following weight gain

(2015) Elisa Fabbrini et al.   JOURNAL OF CLINICAL INVESTIGATION

An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation

(2014) Kae Won Cho et al.   Cell Reports

Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation

(2013) Tuo Deng et al.   Cell Metabolism

Relation Between Serum Free Fatty Acids and Adiposity, Insulin Resistance, and Cardiovascular Risk Factors From Adolescence to Adulthood

(2013) Brigitte I. Frohnert et al.   DIABETES

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

(2013) Shu-Wen Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are there still healthy obese patients?

(2013) Matthias Blüher   Current Opinion in Endocrinology Diabetes and Obesity

Structural and biochemical characteristics of various white adipose tissue depots

(2012) A. Wronska et al.   Acta Physiologica

Dendritic Cells Promote Macrophage Infiltration and Comprise a Substantial Proportion of Obesity-Associated Increases in CD11c+ Cells in Adipose Tissue and Liver

(2012) M. Stefanovic-Racic et al.   DIABETES

Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients

(2012) A. Bertola et al.   DIABETES

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

(2012) Robert W. O'Rourke et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Insulin-sensitive obesity in humans – a ‘favorable fat’ phenotype?

(2012) D. Samocha-Bonet et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

The Metabolically Healthy But Obese Phenotype in African Americans

(2011) Rabia Cherqaoui et al.   Journal of Clinical Hypertension

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

Worsening of Obesity and Metabolic Status Yields Similar Molecular Adaptations in Human Subcutaneous and Visceral Adipose Tissue: Decreased Metabolism and Increased Immune Response

(2010) Eva Klimčáková et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity Increases the Production of Proinflammatory Mediators from Adipose Tissue T Cells and Compromises TCR Repertoire Diversity: Implications for Systemic Inflammation and Insulin Resistance

(2010) H. Yang et al.   JOURNAL OF IMMUNOLOGY

Current concepts in triglyceride metabolism, pathophysiology, and treatment

(2010) Georges AbouRjaili et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

T-Cell Recruitment and Th1 Polarization in Adipose Tissue During Diet-Induced Obesity in C57BL/6 Mice

(2010) Katherine J. Strissel et al.   Obesity

T-Lymphocyte Responses to Intestinally Absorbed Antigens Can Contribute to Adipose Tissue Inflammation and Glucose Intolerance during High Fat Feeding

(2010) Yuehui Wang et al.   PLoS One

Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity

(2009) Carine Duffaut et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

(2009) E. Arner et al.   DIABETES

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

(2009) Guoliang Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signalling pathways in alcohol-induced liver inflammation

(2009) Pranoti Mandrekar et al.   JOURNAL OF HEPATOLOGY

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice

(2009) Yuehui Wang et al.   PLoS One

T-lymphocyte Infiltration in Visceral Adipose Tissue

(2008) Ulrich Kintscher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Obesity and Free Fatty Acids

(2008) Guenther Boden   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE

A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance

(2008) G. Sabio et al.   SCIENCE