Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats

OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis

(2014) Lucile Astorgues-Xerri et al.   EUROPEAN JOURNAL OF CANCER

Effect of dietary fat modification on subcutaneous white adipose tissue insulin sensitivity in patients with metabolic syndrome

(2014) Yolanda Jimenez-Gomez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Sex-Dependent Expression of Caveolin 1 in Response to Sex Steroid Hormones Is Closely Associated with Development of Obesity in Rats

(2014) Rajib Mukherjee et al.   PLoS One

On the Formation of Lipid Droplets in Human Adipocytes: The Organization of the Perilipin–Vimentin Cortex

(2014) Hans Heid et al.   PLoS One

Unraveling galectin-1 as a novel therapeutic target for cancer

(2013) Lucile Astorgues-Xerri et al.   CANCER TREATMENT REVIEWS

Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets

(2013) N. N. Pejnovic et al.   DIABETES

Adipose tissue-specific modulation of galectin expression in lean and obese mice: Evidence for regulatory function

(2013) Davina H. Rhodes et al.   Obesity

Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice

(2013) Jingbo Pang et al.   PLoS One

Serum Heat Shock Protein 70 Concentration in Relation to Polycystic Ovary Syndrome in a Non-Obese Chinese Population

(2013) Hui Gao et al.   PLoS One

Proteomic profiling of lipid droplet-associated proteins in primary adipocytes of normal and obese mouse

(2012) Y. Ding et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Changes in lipid transport-involved proteins of epicardial adipose tissue associated with coronary artery disease

(2012) Antonio Salgado-Somoza et al.   ATHEROSCLEROSIS

Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence

(2012) Koichi Ito et al.   CLINICAL & EXPERIMENTAL METASTASIS

Determination of inflammatory and prominent proteomic changes in plasma and adipose tissue after high-intensity intermittent training in overweight and obese males

(2012) Melanie Leggate et al.   JOURNAL OF APPLIED PHYSIOLOGY

Inhibition of Cell-Free Splicing by Saccharides That Bind Galectins and SR Proteins

(2012) Patricia G. Voss et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Proteomic analysis of rosiglitazone and guggulsterone treated 3T3-L1 preadipocytes

(2012) Pooja Pal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Bromocriptine inhibits adipogenesis and lipogenesis by agonistic action on α2-adrenergic receptor in 3T3-L1 adipocyte cells

(2012) Rajib Mukherjee et al.   MOLECULAR BIOLOGY REPORTS

Identification of Galectin-1 as a Critical Factor in Function of Mouse Mesenchymal Stromal Cell-Mediated Tumor Promotion

(2012) Gábor János Szebeni et al.   PLoS One

TC10 Is Regulated by Caveolin in 3T3-L1 Adipocytes

(2012) Dave Bridges et al.   PLoS One

Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress

(2011) Koichi Ito et al.   ANGIOGENESIS

Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity

(2011) Jorge M. Caviglia et al.   JOURNAL OF LIPID RESEARCH

Profiling of gender-specific rat plasma proteins associated with susceptibility or resistance to diet-induced obesity

(2011) Jung-Won Choi et al.   Journal of Proteomics

Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice

(2011) R.-Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender differences in rat plasma proteome in response to high-fat diet

(2011) Hao Liu et al.   PROTEOMICS

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

(2010) Kimberley A. Stannard et al.   CANCER LETTERS

Serum Galectin-3 Is Elevated in Obesity and Negatively Correlates with Glycosylated Hemoglobin in Type 2 Diabetes

(2010) Johanna Weigert et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Changes in Expression of Skeletal Muscle Proteins between Obesity-Prone and Obesity-Resistant Rats Induced by a High-Fat Diet

(2010) Dong Hyun Kim et al.   JOURNAL OF PROTEOME RESEARCH

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance

(2009) R. Ye et al.   DIABETES

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice

(2009) Feng-Cheng Chou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Bacterial Endotoxin Stimulates Adipose Lipolysis via Toll-Like Receptor 4 and Extracellular Signal-regulated Kinase Pathway

(2009) Luxia Zu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous galectins and the control of the host inflammatory response

(2009) Lucy V Norling et al.   JOURNAL OF ENDOCRINOLOGY

Suppression of Autoimmune Diabetes by Soluble Galectin-1

(2009) M. J. Perone et al.   JOURNAL OF IMMUNOLOGY

Proteomic Analysis of Human Adipose Tissue After Rosiglitazone Treatment Shows Coordinated Changes to Promote Glucose Uptake

(2009) Meftun Ahmed et al.   Obesity

Galectin-Inhibitory Thiodigalactoside Ester Derivatives Have Antimigratory Effects in Cultured Lung and Prostate Cancer Cells

(2008) Tamara Delaine et al.   JOURNAL OF MEDICINAL CHEMISTRY

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH