Expanding the Concept of Chemically Programmable Antibodies to RNA Aptamers: Chemically Programmed Biotherapeutics

An efficient chemical approach to bispecific antibodies and antibodies of high valency

(2009) Julia I. Gavrilyuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

β-Lactam-based approach for the chemical programming of aldolase antibody 38C2

(2009) Julia I. Gavrilyuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Direct Observation of an Enamine Intermediate in Amine Catalysis

(2009) Xueyong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Antibody-Recruiting Small Molecule That Targets HIV gp120

(2009) Christopher G. Parker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer

(2009) Ryan P. Murelli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Instant immunity through chemically programmable vaccination and covalent self-assembly

(2009) M. Popkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-SELEX Chemical Optimization of a Trypanosome-Specific RNA Aptamer

(2008) H. Goringer et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Cell-Specific Induction of Apoptosis by Rationally Designed Bivalent Aptamer-siRNA Transcripts Silencing Eukaryotic Elongation Factor 2

(2008) Ulrich Wullner et al.   CURRENT CANCER DRUG TARGETS

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pegaptanib sodium for the treatment of age-related macular degeneration

(2008) Rajendra S Apte   EXPERT OPINION ON PHARMACOTHERAPY

Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice

(2008) James O. McNamara et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular assembly for high-performance bivalent nucleic acid inhibitor

(2008) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organocatalysis Lost: Modern Chemistry, Ancient Chemistry, and an Unseen Biosynthetic Apparatus

(2007) Carlos F. Barbas   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION