A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones

Synthesis of Natural Product Inspired Compound Collections

(2009) Kamal Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From Machine Learning to Natural Product Derivatives that Selectively Activate Transcription Factor PPARγ

(2009) Matthias Rupp et al.   ChemMedChem

Applications of Integrated Data Mining Methods to Exploring Natural Product Space for Acetylcholinesterase Inhibitors

(2009) Daniela Schuster et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Bioactivity-guided mapping and navigation of chemical space

(2009) Steffen Renner et al.   Nature Chemical Biology

Interactive exploration of chemical space with Scaffold Hunter

(2009) Stefan Wetzel et al.   Nature Chemical Biology

Monoamine oxidase inactivation: From pathophysiology to therapeutics☆

(2008) Marco Bortolato et al.   ADVANCED DRUG DELIVERY REVIEWS

Discovery of a New Class of Inhibitors ofMycobacterium tuberculosisProtein Tyrosine Phosphatase B by Biology-Oriented Synthesis

(2008) Andrea Nören-Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5

(2008) Judith Müller et al.   CHEMBIOCHEM

Signal Transducers and Activators of Transcription as Targets for Small Organic Molecules

(2008) Thorsten Berg   CHEMBIOCHEM

Structure-Based Pharmacophore Screening for Natural-Product-Derived PPARγ Agonists

(2008) Yusuf Tanrikulu et al.   CHEMBIOCHEM

Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein

(2008) Steven Fletcher et al.   ChemMedChem

STAT 3 as a Target for Cancer Drug Discovery

(2008) Luca Costantino et al.   CURRENT MEDICINAL CHEMISTRY

Ligand Binding Efficiency: Trends, Physical Basis, and Implications

(2008) Charles H. Reynolds et al.   JOURNAL OF MEDICINAL CHEMISTRY

Scaffold diversity of natural products: inspiration for combinatorial library design

(2008) Kristina Grabowski et al.   NATURAL PRODUCT REPORTS

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE

In silicoTarget Fishing for Rationalized Ligand Discovery Exemplified on Constituents ofRuta graveolens

(2008) Judith Rollinger et al.   PLANTA MEDICA