Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment

β-Arrestin-2 knockout prevents development of cellular μ-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons

(2014) M Connor et al.   BRITISH JOURNAL OF PHARMACOLOGY

Principles of Opioid Use in Cancer Pain

(2014) Russell K. Portenoy et al.   JOURNAL OF CLINICAL ONCOLOGY

Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease

(2014) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and D1-NMDA Receptors in the mPFC

(2014) Hirotake Hida et al.   NEUROPSYCHOPHARMACOLOGY

Opioid receptor desensitization: mechanisms and its link to tolerance

(2014) Stéphane Allouche et al.   Frontiers in Pharmacology

FACS Array Profiling Identifies Ecto-5' Nucleotidase as a Striatopallidal Neuron-Specific Gene Involved in Striatal-Dependent Learning

(2013) S. L. Ena et al.   JOURNAL OF NEUROSCIENCE

Comparison of tolerance to morphine-induced respiratory and analgesic effects in mice

(2013) Wasseem Mohammed et al.   TOXICOLOGY LETTERS

Chronic Opioid Potentiates Presynaptic but Impairs PostsynapticN-Methyl-d-aspartic Acid Receptor Activity in Spinal Cords

(2012) Yi-Lin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Senegenin Attenuates Hepatic Ischemia-Reperfusion Induced Cognitive Dysfunction by Increasing Hippocampal NR2B Expression in Rats

(2012) Weibin Xie et al.   PLoS One

Recovery from  -Opioid Receptor Desensitization after Chronic Treatment with Morphine and Methadone

(2011) N. Quillinan et al.   JOURNAL OF NEUROSCIENCE

The Mu-Opioid Receptor and the NMDA Receptor Associate in PAG Neurons: Implications in Pain Control

(2011) María Rodríguez-Muñoz et al.   NEUROPSYCHOPHARMACOLOGY

Nr4a1-eGFP Is a Marker of Striosome-Matrix Architecture, Development and Activity in the Extended Striatum

(2011) Margaret I. Davis et al.   PLoS One

Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant μ-opioid receptor

(2009) Li He et al.   FASEB JOURNAL

Drebrin a knockout eliminates the rapid form of homeostatic synaptic plasticity at excitatory synapses of intact adult cerebral cortex

(2009) Chiye Aoki et al.   JOURNAL OF COMPARATIVE NEUROLOGY

μ-Opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2

(2009) Thomas Koch et al.   JOURNAL OF NEUROCHEMISTRY

Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance

(2008) Shanelle W Ko et al.   Molecular Brain

Region-dependent attenuation of μ opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance

(2007) L J Sim-Selley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Morphine-induced analgesic tolerance, locomotor sensitization and physical dependence do not require modification of mu opioid receptor, cdk5 and adenylate cyclase activity

(2007) Candice Contet et al.   NEUROPHARMACOLOGY