Article
Anesthesiology
Susana Pacreu, Esther Vila, Luis Molto, Juan Fernandez-Candil, Beatriz Fort, Yiyang Lin, Alba Leon
Summary: This study aimed to investigate the effect of dexmedetomidine on intraoperative neurophysiological monitoring during brain stem and supratentorial cranial surgery. The results showed that dexmedetomidine administration at a dosage of 0.5 mcg/kg/h may reduce propofol requirements and have adverse effects on some neuromonitoring variables, but could be considered as an alternative for IONM during cranial surgeries.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2021)
Article
Anesthesiology
Xiang Bingbing, Jiao Shulan, Zhang Yulong, Wang Lu, Yao Yuting, Yuan Feng, Chen Rui, Zhou Qijun
Summary: Studies have shown that both desflurane and sevoflurane have a dose-dependent inhibitory effect on SEPs and MEPs during neurosurgery, with desflurane appearing to have a stronger inhibitory effect at the same MAC concentration compared to sevoflurane.
BMC ANESTHESIOLOGY
(2021)
Article
Cell Biology
Samantha M. Russman, Daniel R. Cleary, Youngbin Tchoe, Andrew M. Bourhis, Brittany Stedelin, Joel Martin, Erik C. Brown, Xinlian Zhang, Aaron Kawamoto, Won Hyung A. Ryu, Ahmed M. Raslan, Joseph D. Ciacci, Shadi A. Dayeh
Summary: A new microelectrode array technology was used to improve understanding of human spinal cord neurophysiology through high-definition spatiotemporal dynamics and postoperative recording of electrophysiological responses. This technology has high sensitivity and can provide finer electrophysiological markers than traditional methods.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Clinical Neurology
Hongli Yue, Man Zhou, Yingzi Chong, Miao Cheng, Hui Qiao, Yu Lu, Weihua Cui
Summary: This study aims to evaluate the effects of intravenous infusion of lidocaine on SEPs and MEPs during intraspinal tumour resection to determine whether electrophysiological monitoring can accurately reflect the integrity of nerve functions while infusing lidocaine, and explore the possibility of lidocaine use as an anaesthesia option during intraspinal tumour resection.
JOURNAL OF PAIN RESEARCH
(2022)
Review
Clinical Neurology
Rajiv P. Reddy, Anya Singh-Varma, Robert Chang, Abhinav Vedire, Katherine M. Anetakis, Jeffrey R. Balzer, Donald J. Crammond, Varun Shandal, Joon Y. Lee, Jeremy D. Shaw, Parthasarathy D. Thirumala
Summary: This systematic review and meta-analysis aimed to evaluate the predictive value of transcranial motor evoked potential (TcMEP) monitoring for postoperative neurologic complications in patients undergoing cervical spine decompression surgery. The analysis of 19 studies with 4608 patients showed that TcMEP monitoring has high specificity but low sensitivity for predicting postoperative neurological deficit. Irreversible TcMEP changes indicated a much higher risk of deficit than reversible TcMEP changes.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Zhenxing Zhang, Yi Wang, Tao Luo, Huaguang Qi, Lin Cai, Yang Yuan, Jingfeng Li
Summary: The aim of this study was to assess the value of dermatomal somatosensory evoked potentials (DSEPs) and cortical somatosensory evoked potentials (SSEPs) in monitoring spinal cord function for patients with congenital scoliosis (CS). The study found that DSEPs are more sensitive to microscopic posterior column dysfunction in CS patients that cannot be detected by either radiology or routine clinical examination. Therefore, preoperative DSEPs assessment is recommended for intraoperative monitoring.
Article
Clinical Neurology
Tun Liu, Buhuai Dong, Huaguang Qi, Liang Yan, Songchuan Zhao, Zhian Liu, Xuemei Liu, Fei Wang, Liang Li, Wenbo Cai, Zhenguo Luo, Gang Wang
Summary: This retrospective study aimed to explore the relation between SEPs and MEPs and thoracic cord function in thoracic spinal decompression surgery. The results suggest that combined monitoring of SEPs and MEPs is important for evaluating postoperative prognosis, and recording SEPs at the T4 time point is more accurate for predicting patients' prognosis.
Review
Clinical Neurology
Marko Mijic, Andres Jung, Benedikt Schoser, Peter Young
Summary: This study systematically reviewed the role of peripheral electrical stimulation (PES) in changing somatosensory evoked potentials (SEP) in healthy subjects and stroke patients. The results suggest a correlation between sensory and motor function assessments and changes in SEP components. However, further randomized controlled trials are needed to verify the relationship between SEP, sensory reorganization, and cortical plasticity.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Nitin Agarwal, Saman Shabani, Jeremy Huang, Alma Rechav Ben-Natan, Praveen V. Mummaneni
Summary: Literature opinions on the use of IOMN are divided. MEP monitoring can serve as a diagnostic test, but its sensitivity and specificity vary based on various risk factors. To determine the effectiveness of IONM, it is recommended to implement a standardized neuromonitoring procedure and gather data. Additionally, implementing a standardized IONM plan may increase interdisciplinary cooperation among the surgical team and contribute to further advancements in IONM.
NEUROLOGIC CLINICS
(2022)
Article
Anesthesiology
Haiyang Liu, Minyu Jian, Chengwei Wang, Lanyi Nie, Fa Liang, Kuo Liu, Kaiying Zhang, Hui Qiao, Ruquan Han
Summary: In this randomized controlled trial, the researchers investigated whether sugammadex could reverse the rocuronium-induced suppression of TceMEP amplitude in patients undergoing spine surgery. The results showed that sugammadex effectively reversed the moderate neuromuscular blockade induced by rocuronium, suggesting its potential use in enhancing TceMEP waveform monitoring during spine surgery.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2023)
Article
Clinical Neurology
Angelo Insola, Paolo Mazzone, Eugenio Scarnati, Domenico Restuccia, Massimiliano Valeriani
Summary: This study investigated the subcortical somatosensory evoked potentials in Parkinson's disease patients. Results showed different responses to muscle or cutaneous afferent stimulation, providing insights into subcortical processing of somatosensory input.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Vani Vijay, Anoop Thomas, Sajesh K. Menon
Summary: This case illustrates that changes in MEPs can occur even at early stages in more vulnerable cases and should be monitored to avoid disability.
Review
Anesthesiology
Sirima Phoowanakulchai, Masahiko Kawaguchi
Summary: This review aims to explore the considerations involved in achieving optimal Tc-MEP monitoring while ensuring patient safety. Critical factors include preoperative patient selection, comorbidity assessment, motor power evaluation, and the nature of the planned surgery. Accurate paralysis assessment, continuous NMBA infusion, and post-tetanic stimulation techniques are essential for achieving optimal partial NMB. The decision to administer an NMB during Tc-MEP monitoring requires a careful evaluation of the balance between accuracy and potential complications.
JOURNAL OF ANESTHESIA
(2023)
Article
Neurosciences
Edyta Dziadkowiak, Marta Waliszewska-Prosol, Malgorzata Wieczorek, Joanna Bladowska, Slawomir Budrewicz, Maria Ejma
Summary: The study identified significant changes in multiple parameters of visually evoked potentials, brainstem auditory evoked potentials, and somatosensory evoked potentials in patients with myasthenia gravis, suggesting disturbances in the bioelectric activities of the central and peripheral nervous system.
Article
Anesthesiology
Xinyu Jiang, Xiaoning Tang, Shaoquan Liu, Ling Liu
Summary: The effects of different doses of dexmedetomidine on evoked potentials during spinal surgery were investigated. The results showed that low-dose Dex had no effect on somatosensory evoked potentials (SEPs) monitoring, while high-dose Dex may increase the rate of false positive transcranial motor evoked potentials (tcMEPs) signals and the incidence of intraoperative hypertension.
BMC ANESTHESIOLOGY
(2023)
Article
Anesthesiology
Alparslan Turan, Amanda S. Artis, Cecelia Hanline, Partha Saha, Kamal Maheshwari, Andrea Kurz, P. J. Devereaux, Emmanuelle Duceppe, Ameen Patel, Maria Tiboni, Kurt Ruetzler, Rupert Pearse, Matthew T. V. Chan, William K. K. Wu, Sadeesh Srinathan, Amit X. Garg, Robert Sapsford, Daniel I. Sessler
Article
Anesthesiology
Tanya J. Symons, Nikolajs Zeps, Paul S. Myles, Jonathan M. Morris, Daniel I. Sessler
Review
Anesthesiology
Daniel I. Sessler
Summary: The esophagus and nasopharynx are ideal sites for temperature monitoring during general anesthesia, while alternatives for neuraxial anesthesia and postoperative care include oral and axillary temperatures, as well as zero-heat flux forehead temperature.
Article
Anesthesiology
Ryan M. Hijazi, Daniel I. Sessler, Chen Liang, Fabio A. Rodriguez-Patarroyo, Edward G. Soltesz, Andra E. Duncan
Summary: This study found no significant difference in mortality and cardiac complications between patients undergoing cardiac surgeries in the morning and afternoon. The timing of surgery did not alter postoperative risk according to the results.
Article
Anesthesiology
Lukas Martin Mueller-Wirtz, Daniel Kiefer, Felix Maurer, Maximilian Alexander Floss, Jonas Doneit, Tobias Hueppe, Theodora Shopova, Beate Wolf, Daniel I. Sessler, Thomas Volk, Sascha Kreuer, Tobias Fink
Summary: Exhaled pentanal may serve as a potential biomarker for early detection of ventilator-induced lung injury in rats. Ventilation at high tidal volumes led to significantly increased exhaled pentanal concentrations, while short-term ventilation at high tidal volumes did not result in significant increases in white blood cell concentrations and cleaved caspase 3 in lung tissue.
ANESTHESIA AND ANALGESIA
(2021)
Letter
Anesthesiology
Daniel I. Sessler, Rod J. Nault
Letter
Anesthesiology
Kamal Maheshwari, Zhongping Jian, Daniel I. Sessler
Editorial Material
Anesthesiology
Donal J. Buggy, Bernhard Riedel, Daniel I. Sessler
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Anesthesiology
Shobana Rajan, Sanchit Ahuja, Barak Cohen, Adriana Martin, Amanda Pursell, Chen Liang, Guangmei Mao, Ryu Komatsu, Ehab Farag, Daniel I. Sessler
Summary: There was no significant difference in the risk of postoperative stroke after non-neurological, noncarotid, and noncardiac surgeries between patients who used ACEIs or ARBs for a long time and those who did not.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Lukas M. Muller-Wirtz, Daniel Kiefer, Joschua Knauf, Maximilian A. Floss, Jonas Doneit, Beate Wolf, Felix Maurer, Daniel I. Sessler, Thomas Volk, Sascha Kreuer, Tobias Fink
Summary: High inspired oxygen during mechanical ventilation can affect exhalation of breath biomarkers and induce systemic inflammation. Pentanal exhalation increases during ventilation, while hexanal shows a slight increase at high inspired oxygen levels.
Article
Anesthesiology
James S. Khan, Daniel I. Sessler, Matthew T. V. Chan, C. Y. Wang, Ignacio Garutti, Wojciech Szczeklik, Alparslan Turan, Jason W. Busse, D. Norman Buckley, James Paul, Michael McGillion, Carmen Fernandez-Riveira, Sadeesh K. Srinathan, Harsha Shanthanna, Ian Gilron, Michael Jacka, Paul Jackson, James Hankinson, Pilar Paniagua, Shirley Pettit, P. J. Devereaux
Summary: This study investigated the incidence, characteristics, impact, and risk factors associated with persistent incisional pain in patients aged 45 years and older who underwent major inpatient noncardiac surgery. The results showed that female sex, Asian ethnicity, history of chronic pain, specific types of surgery, and postoperative analgesia were associated with an increased risk of persistent pain. It was found that persistent incisional pain affected daily activities and led to increased analgesic consumption, indicating significant morbidity.
Article
Anesthesiology
Tetsuya Shimada, Edward J. Mascha, Dongsheng Yang, Mauro Bravo, Eva Rivas, Ilker Ince, Alparslan Turan, Daniel I. Sessler
Summary: This study aimed to evaluate whether intra-operative hypertension causes postoperative complications. The results showed that there was no clinically meaningful relationship between intra-operative systolic pressure and the composite of myocardial injury and mortality, or acute kidney injury, and there was no interaction with preoperative clinic blood pressure.
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
(2022)
Article
Anesthesiology
Gausan Ratna Bajracharya, Wael Ali Sakr Esa, Guangmei Mao, Steve Leung, Barak Cohen, Kamal Maheshwari, Hermann P. Kessler, Emre Gorgun, Daniel I. Sessler, Alparslan Turan
Summary: This study investigated the effect of regional analgesia on postoperative infections in patients undergoing colorectal surgery. The results showed no significant difference in the occurrence of serious infections between patients with regional analgesia and patients with IV-PCA. Therefore, regional analgesia should not be chosen as a postoperative analgesic technique to reduce infections.
BRAZILIAN JOURNAL OF ANESTHESIOLOGY
(2023)
Article
Medicine, General & Internal
Mark D. Neuman, Rui Feng, Susan S. Ellenberg, Frederick Sieber, Daniel I. Sessler, Jay Magaziner, Nabil Elkassabany, Eric S. Schwenk, Derek Dillane, Edward R. Marcantonio, Diane Menio, Sabry Ayad, Manal Hassan, Trevor Stone, Steven Papp, Derek Donegan, Mitchell Marshall, J. Douglas Jaffe, Charles Luke, Balram Sharma, Syed Azim, Robert Hymes, Ki-Jinn Chin, Richard Sheppard, Barry Perlman, Joshua Sappenfield, Ellen Hauck, Mark A. Hoeft, Ann Tierney, Lakisha J. Gaskins, Annamarie D. Horan, Trina Brown, James Dattilo, Jeffrey L. Carson
Summary: Results from the study showed that spinal anesthesia led to more severe pain in the first 24 hours after surgery and higher prescription analgesic use at 60 days compared to general anesthesia, but satisfaction was similar between the two groups.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Anesthesiology
Ryu Komatsu, Huseyin Oguz Yilmaz, Natalya Makarova, Alparslan Turan, Daniel I. Sessler, Shobana Rajan, Maged Argalious
Summary: Preoperative statin use in noncardiac surgical patients was associated with slightly reduced odds of postoperative respiratory, infectious, and cardiovascular complications. However, the number needed to treat was high.
ANESTHESIA AND ANALGESIA
(2021)