Article
Materials Science, Multidisciplinary
Jacopo Emilio Giaretta, Farshad Oveissi, Fariba Dehghani, Sina Naficy
Summary: The article presents a 3D printable paper-based sensor for detecting H2O2, which simplifies the fabrication process and detects H2O2 concentration by observing the change in resistance. The integration of enzyme enhances the detection performance of the sensor.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Chemistry, Analytical
Shaoyong Cai, Qiang Zhang, Cheng Chen, Jinglu Wang, Baoying Lin, Xijing Liu, Xinyu Sun, Xinghai Liu, Liangzhe Chen
Summary: In this study, Zntpp particles are anchored on the PPy network to form a Pzt sensor with wrinkle-like nanostructure. The Pzt sensor demonstrates outstanding response towards ammonia with short response/recovery time. It has good durability and stability and can detect trace ammonia in livestock farming. A wireless sensor device is also developed to precisely read concentration information in real-time using a smartphone, showing great application prospects in the field of livestock farming.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Biophysics
Patta Supraja, Suryasnata Tripathy, Ranjana Singh, Vikrant Singh, Gajendranath Chaudhury, Shiv Govind Singh
Summary: This study presents a label-free method for simultaneous detection of Alzheimer's disease-specific biomarkers A beta 40 and A beta 42 peptides using polypyrrole nanoparticle-based chemiresistive biosensors on a single platform. The method can detect A beta 40 and A beta 42 in spiked-plasma within a range of 10(-14) - 10(-6) g/mL, with low detection limits, enabling the estimation of diagnostically significant A beta 42/A beta 40 ratio.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Chochanon Moonla, Suphaporn Chenkhuruthum, Tik Ouiram, Anchana Preechaworapun, Weerinradah Tapala, Kamonwad Ngamchuea, Tanin Tangkuaram
Summary: In this study, a label-free immunosensor for rapid detection of CEA was developed using a biocomposite material. The immunosensor exhibited a wide linear range, high sensitivity, low detection limit, excellent selectivity, stability, and repeatability. The proposed method was successfully applied for CEA detection in whole blood samples, suggesting its potential for real sample analysis.
Review
Chemistry, Analytical
Maria Maddalena Calabretta, Martina Zangheri, Donato Calabria, Antonia Lopreside, Laura Montali, Elisa Marchegiani, Ilaria Trozzi, Massimo Guardigli, Mara Mirasoli, Elisa Michelini
Summary: Significant progress has been made in the development of paper-based analytical devices for point-of-care applications, particularly in chemiluminescent immunoassays-based techniques. However, the diffusion of these devices into everyday life has not kept pace with scientific production. Targeted research is needed to address the barriers hindering the widespread application of these methods in routine analysis.
Article
Chemistry, Analytical
Hiroto Okuyama, Takanori Tamaki, Yuhei Oshiba, Hiroshi Ueda, Takeo Yamaguchi
Summary: A numerical model was presented to systematically design an improved recognition system for a flow-through biosensor, successfully addressing a bottleneck step in sandwich-type detection and achieving a signal comparable to that of a conventional enzyme-linked immunosorbent assay within a short time. The problem can be solved by adopting appropriate receptors and analytical conditions, fulfilling the sensitivity requirements for POCT.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Physical
Jasmina Vidic, Marisa Manzano
Summary: Electrochemical biosensors offer a rapid and accurate means of detecting pathogens, with applications in clinical, environmental, and food industry sectors. Utilizing screen-printed electrodes in conjunction with nanoparticles can enhance signal and sensitivity, while functionalizing the working electrodes ensures highly specific pathogen detection.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Article
Engineering, Electrical & Electronic
Natalia Tokranova, Nathaniel Cady, Avery Lamphere, Igor A. Levitsky
Summary: This article presents a highly sensitive detection method for fentanyl using nanoporous silicon and specific antibody functionalization. The electrochemical sensor and square wave voltammetry are employed to detect low concentrations of fentanyl in phosphate buffer and human sweat. The future goal is to develop a wearable sweat sensor array for rapid on-site detection of multiple opioids.
IEEE SENSORS JOURNAL
(2022)
Article
Multidisciplinary Sciences
Hong Zhang, Zuobin Zhang, Zhou Li, Hongjie Han, Weiguo Song, Jianxin Yi
Summary: Highly efficient gas sensors capable of detecting and identifying hazardous gases are crucial for various applications. This study presents a sensor with multiple chemiresistive and potentiometric outputs, allowing discriminative gas detection with tailored sensing patterns. The sensor demonstrates superior sensing and discrimination capabilities, enabling accurate and early warning of fire hazards.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Patricia Bento da Silva, Jaqueline Rodrigues da Silva, Mosar Correa Rodrigues, Julia Augusto Vieira, Ikaro Alves de Andrade, Tatsuya Nagata, Alexandre Silva Santos, Sebastiao William da Silva, Marcia Cristina Oliveira da Rocha, Sonia Nair Bao, Pedro M. Moraes-Vieira, Jose Proenca-Modena, Monara K. C. Angelim, Gabriela Fabiano de Souza, Stefanie Primon Muraro, Andre Luis Branco de Barros, Glendara Aparecida de Souza Martins, Fatima Ribeiro-Dias, Giovanna Machado, Melissa Regina Fessel, Ana Marisa Chudzinski-Tavassi, Celia Machado Ronconi, Debora Goncalves, Rui Curi, Osvaldo N. Oliveira Jr, Ricardo Bentes Azevedo
Summary: A low-cost immunoassay using dynamic light scattering (DLS) was developed for the rapid detection of SARS-CoV-2 within 30 minutes. The immunosensor, composed of gold nanoparticles functionalized with antibodies, demonstrated specific binding to the virus and a limit of detection of 5.29 x 10(3) TCID50/mL. This technology can be extended to other detection principles, providing a potential solution for low-cost mass testing for COVID-19.
Article
Chemistry, Analytical
Qiao Wang, Ruixia Li, Peizhe Wang, Yaxiong Zhang, Yanrong Wang, Yifan Yang, Zhengkun Wu, Beixi An, Jianjun Li, Erqing Xie
Summary: Nitrogen dioxide (NO2), a hazardous gas released by human activities, can be detected using sensors made of Au decorated WO3. The sensing performance of Au-WO3 sensors (Rg/Ra = 4.3@ 1 ppb, 746.0@ 5 ppm) is better than that of pristine WO3 (Rg/Ra = 1.2@ 1 ppb). Ex-situ X-ray photoelectron spectroscopy and density functional theory were used to analyze the dynamic processes and electron transfer sensing process in Au-WO3-3 during NO2 sensing reactions. The effects of oxygen partial pressure and relative humidity on the sensing performance were also studied. The enhanced sensing mechanisms of Au-WO3 sensors are attributed to electronic and chemical sensitization effects, increased number of active sites, decreased activation energy, and three-dimensional hierarchical structure.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Materials Science, Multidisciplinary
Wei Liu, Ding Gu, Jian-Wei Zhang, Xiao-Gan Li, Marina N. Rumyantseva, Alexander M. Gaskov
Summary: Novel ZnSe/NiO heterostructure nanocomposites were prepared successfully by one-step hydrothermal method. The sensor exhibited high response to NO2 and excellent selectivity to possible interferents, making it suitable for detecting low concentrations of NO2.
Article
Chemistry, Multidisciplinary
Ashraf Ali, Yaser E. Greish, Reem H. Alzard, Lamia A. Siddig, Ahmed Alzamly, Naser Qamhieh, Saleh T. Mahmoud
Summary: A sensor using acetone as a biomarker has been developed, exhibiting high selectivity, long-term stability, and repeatability, as well as ultra-fast response and recovery times, flexibility, and ease of fabrication, making it suitable for real-time breath analysis.
Article
Engineering, Electrical & Electronic
Kampara Roopa Kishore, D. Balamurugan, B. G. Jeyaprakash
Summary: In this study, PVA/CdO nanofibers were successfully deposited on a glass substrate using an electrospinning method and further processed to yield one-dimensional CdO nano-grains. The calcined CdO showed enhanced response towards formaldehyde vapour at elevated temperatures. The composition, morphology, and sensing mechanism were analyzed and reported.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2021)
Article
Chemistry, Multidisciplinary
Jiran Li, Peter B. Lillehoj
Summary: A simple electrothermal flow-enhanced biosensor was developed for ultrafast, high sensitivity measurements of protein biomarkers in whole blood, without requiring blood purification or lengthy incubation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Cell & Tissue Engineering
Christopher B. Horner, Koji Hirota, Junze Liu, Maricela Maldonado, B. Hyle Park, Jin Nam
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2018)
Article
Cell & Tissue Engineering
Maricela Maldonado, Rebeccah J. Luu, Gerardo Ico, Alex Ospina, Danielle Myung, Hung Ping Shih, Jin Nam
STEM CELL RESEARCH & THERAPY
(2017)
Article
Cell & Tissue Engineering
Karen Low, Lauren Y. Wong, Maricela Maldonado, Chetas Manjunath, Christopher B. Horner, Mark Perez, Nosang V. Myung, Jin Nam
Article
Engineering, Biomedical
Alexander R. Brunelle, Christopher B. Horner, Karen Low, Gerardo Ico, Jin Nam
ACTA BIOMATERIALIA
(2018)
Article
Chemistry, Multidisciplinary
T. Lim, G. Ico, K. Jung, K. N. Bozhilov, J. Nam, A. A. Martinez-Morales
Article
Chemistry, Multidisciplinary
G. Ico, A. Myung, B. S. Kim, N. V. Myung, J. Nam
Article
Nanoscience & Nanotechnology
Christopher B. Homer, Maricela Maldonado, Youyi Tai, R. M. Imtiaz Karim Rony, Jin Nam
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Nanoscience & Nanotechnology
Aihik Banerjee, Tanvi Jariwala, Youn-Kyung Baek, Dung Thi Hanh To, Youyi Tai, Junze Liu, Hyle Park, Nosang Myung, Jin Nam
Summary: The drawbacks of conventional drug administration are addressed by a magneto-, opto-stimuli responsive drug delivery system based on functionalized electrospun nanofibers with superparamagnetic iron oxide nanoparticles. This system allows on-demand drug delivery at specific times, overcoming the limitations of traditional drug delivery methods.
Article
Engineering, Biomedical
Youyi Tai, Gerardo Ico, Karen Low, Junze Liu, Tanvi Jariwala, David Garcia-Viramontes, Kyu Hwan Lee, Nosang V. Myung, B. Hyle Park, Jin Nam
Summary: The study introduces a functional material-based technology to develop patient-specific in vitro neural models, utilizing hydro-acoustic actuation to remotely activate the piezoelectric effect of P(VDF-TrFE) scaffolds for multi-phenotypic differentiation of neural stem cells. The mechano-electrical stimulation induced by the deflection of the scaffold leads to enhanced interactions among cellular components, resulting in improved neural connectivity and functionality in the 3D neuron-glial interface.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Polymer Science
Youyi Tai, Aihik Banerjee, Robyn Goodrich, Lu Jin, Jin Nam
Summary: Polymeric biomaterials with chemical modification have been used to functionalize scaffolds for cell and tissue engineering applications. However, due to the complexity of in vivo cellular microenvironments, additional physical stimuli are often necessary to further enhance tissue and cell behaviors. The incorporation of extrinsic stimuli into functionalized polymeric scaffold systems shows significant improvements in cell proliferation, differentiation, and tissue functionalities.
Article
Materials Science, Multidisciplinary
Sooyoun Yu, Joanna Milam-Guerrero, Youyi Tai, Steve Yang, Yun Young Choi, Jin Nam, Nosang Myung
Summary: This study systematically investigated the size- and conformation-dependent piezoelectric properties of polyacrylonitrile (PAN) nanofibers. It was found that the electrospinning process and post-thermal treatment could increase the proportion of the electroactive phase in the nanofibers, leading to a higher piezoelectric charge constant.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Robyn Goodrich, Youyi Tai, Zuyang Ye, Yadong Yin, Jin Nam
Summary: The biophysical microenvironment of cells during embryonic development undergoes dynamic changes, resulting in tissue specification. A versatile magneto-responsive hydrogel system composed of magnetic nanorods and a stress-responsive polymeric matrix is developed to regulate the physical stem cell niche. The system utilizes the anisotropic magnetic/shape factor of the nanorods to maximize strains on the polymeric network, allowing for precise control of hydrogel modulus. It also enables fast and reversible responses under magnetic fields and spatially controlled heterogeneity of modulus within the hydrogel.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Zhongxiang Wang, Youyi Tai, Jin Nam, Yadong Yin
Summary: This study investigates the evolution of size, morphology, phase, and surface properties of Mn2+-doped ZnS nanorods during calcination. It reveals a complex dependence of phase and ML performance on various factors. The phase composition has a significant impact on ML intensity, while photoluminescence is affected by optical absorption from carbon species generated by surface ligands.
CHEMISTRY OF MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Tanvi Jariwala, Gerardo Ico, Youyi Tai, Honghyun Park, Nosang Myung, Jin Nam
Summary: The utilization of piezoelectric electrospun nanofibers for drug delivery applications demonstrates ultra-sensitivity and mechanical responsiveness, allowing for drug release modulation through management of fiber diameter and applied pressure/shockwave dose.
ACS APPLIED BIO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Sanggon Kim, Gerardo Ico, Yaocai Bai, Steve Yang, Jung-Ho Lee, Yadong Yin, Nosang V. Myung, Jin Nam
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)