Synthesis, DNA Binding, and Antiproliferative Activity of Novel Acridine-Thiosemicarbazone Derivatives

Design, synthesis, characterization, cytotoxic and structure activity relationships of novel Ru(II) complexes

(2015) Sreekanth Thota et al.   CHINESE CHEMICAL LETTERS

Synthesis and characterization of thiosemicarbazonato molybdenum(VI) complexes: In vitro DNA binding, cleavage, and antitumor activities

(2015) Mouayed A. Hussein et al.   POLYHEDRON

Synthesis, characterization, crystal structure and cytotoxic properties of thiosemicarbazide Ni(II) and Zn(II) complexes

(2015) S. Mathan Kumar et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Design and synthesis of novel 5,6-disubstituted pyridine-2,3-dione-3-thiosemicarbazone derivatives as potential anticancer agents

(2014) Wenlin Xie et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel R-(+)-limonene-based thiosemicarbazones and their antitumor activity against human tumor cell lines

(2014) Fábio Vandresen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling

(2014) Antonio Rescifina et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of platinum(II) complexes of isatin thiosemicarbazones derivatives: In vitro anti-cancer and deoxyribose nucleic acid binding activities

(2014) Amna Qasem Ali et al.   INORGANICA CHIMICA ACTA

Thiosemicarbazone Cu(II) and Zn(II) complexes as potential anticancer agents: Syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction activity

(2014) Jia Shao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Targeting abasic site-containing DNA with annelated quinolizinium derivatives: the influence of size, shape and substituents

(2014) Katja Benner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of copper(II) complexes of isatin thiosemicarbazone derivatives: In vitro anti-cancer, DNA binding, and cleavage activities

(2014) Amna Qasem Ali et al.   POLYHEDRON

Synthesis, spectroscopic, anticancer and antibacterial studies of Ni(II) and Cu(II) complexes with 2-carboxybenzaldehyde thiosemicarbazone

(2014) Sulekh Chandra et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Synthesis of isatin thiosemicarbazones derivatives: In vitro anti-cancer, DNA binding and cleavage activities

(2014) Amna Qasem Ali et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Synthesis and antiproliferative activity of some steroidal thiosemicarbazones, semicarbazones and hydrozones

(2014) Chunfang Gan et al.   STEROIDS

Radiochemotherapy plus 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in advanced-stage cervical and vaginal cancers

(2013) Charles A. Kunos et al.   GYNECOLOGIC ONCOLOGY

Spectroscopic study one thiosemicarbazone derivative with ctDNA using ethidium bromide as a fluorescence probe

(2013) Shaoguang Geng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Spectroscopic, Viscositic and Molecular Modeling Studies on the Interaction of 3′-Azido-Daunorubicin Thiosemicarbazone with DNA

(2013) Fengling Cui et al.   JOURNAL OF FLUORESCENCE

Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery

(2013) Jia Sheng et al.   MEDICINAL RESEARCH REVIEWS

Synthesis, DNA Binding and Topoisomerase I Inhibition Activity of Thiazacridine and Imidazacridine Derivatives

(2013) Elizabeth Lafayette et al.   MOLECULES

DNA-intercalator interactions: structural and physical analysis using atomic force microscopy in solution

(2013) M. Maaloum et al.   Soft Matter

Iron Chelators with Topoisomerase-Inhibitory Activity and Their Anticancer Applications

(2012) V. Ashutosh Rao   ANTIOXIDANTS & REDOX SIGNALING

Amsacrine as a Topoisomerase II Poison: Importance of Drug–DNA Interactions

(2012) Adam C. Ketron et al.   BIOCHEMISTRY

Synthesis and cytotoxic activity of new acridine-thiazolidine derivatives

(2012) Francisco W.A. Barros et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Iron Chelators for the Treatment of Cancer

(2012) Y. Yu et al.   CURRENT MEDICINAL CHEMISTRY

3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

(2012) Jana Plsikova et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mechanistic Studies of Semicarbazone Triapine Targeting Human Ribonucleotide Reductasein Vitroand in Mammalian Cells

(2012) Yimon Aye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of amsacrine binding with DNA using UV–visible, circular dichroism and Raman spectroscopic techniques

(2012) Deepak Kumar Jangir et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Synthesis, characterization, fluorescence and DNA-binding studies of europium(III) pirates complexes with amide-based 2,3-dihydroxynaphthalene derivatives

(2012) Hanyu LI et al.   JOURNAL OF RARE EARTHS

Cytotoxic 3,6-bis((imidazolidinone)imino)acridines: Synthesis, DNA binding and molecular modeling

(2011) Ladislav Janovec et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Medicinal Chemistry of Novel Iron Chelators for the Treatment of Cancer

(2011) Zaklina Kovacevic et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

DNA binding, protein interaction, radical scavenging and cytotoxic activity of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde(2′-hydroxybenzoyl)hydrazone and its Cu(II) complexes: A structure activity relationship study

(2011) Duraisamy Senthil Raja et al.   INORGANICA CHIMICA ACTA

Studies of the fluorescence light-up effect of amino-substituted benzo[b]quinolizinium derivatives in the presence of biomacromolecules

(2011) Katja Faulhaber et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents

(2010) Chunmei Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles

(2010) André P. Liesen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Co(III), Ni(II), Zn(II) and Cd(II) complexes with 2-acetyl-2-thiazoline thiosemicarbazone: Synthesis, characterization, X-ray structures and antibacterial activity

(2010) E. Viñuelas-Zahínos et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclopalladated complexes containing tridentate thiosemicarbazone ligands of biological significance: Synthesis, structure and antimalarial activity

(2010) Prinessa Chellan et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

N(4)-tolyl-2-benzoylpyridine-derived thiosemicarbazones and their palladium(II) and platinum(II) complexes: Cytotoxicity against human solid tumor cells

(2010) Karina O.S. Ferraz et al.   POLYHEDRON

Interaction of ethidium bromide and caffeine with DNA in aqueous solution

(2009) S. F. Baranovsky et al.   Journal of Applied Spectroscopy

Synthesis and antitumor activity of novel amsacrine analogs: The critical role of the acridine moiety in determining their biological activity

(2008) Adriana Chilin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones

(2008) Kesavan Krishnan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS