Journal
ANALYTICAL METHODS
Volume 4, Issue 6, Pages 1612-1615Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ay25320h
Keywords
-
Funding
- National Natural Science Foundation of China [20872137/B020402]
- China Postdoctoral Science Foundation [2011M501421]
- US National Institutes of Health [GM089557]
Ask authors/readers for more resources
Target protein-magnetic nanoparticle (MNP) conjugates, i.e. alpha-glucosidase-MNP and protein tyrosine phosphatase 1B (PTP1B)-MNP, were prepared and evaluated for the first time for affinity extraction of enzyme inhibitors from herbal extracts. Four ligands extracted from Granati pericarpium were identified by ESI-MS analysis. In vitro tests indicated that they inhibited both a-glucosidase and PTP1B, two important target proteins for diabetic treatment.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
