Journal
ANALYTICAL METHODS
Volume 4, Issue 7, Pages 2141-2144Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ay25075f
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Funding
- UK National Measurement System
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Urine is a preferred specimen for nucleic acid-based detection of sexually transmitted infections (STIs) but represents a challenge for microfluidic devices due to low analyte concentrations. We present an extraction methodology enabling rapid on-chip nucleic acid purification directly from clinically relevant sample volumes up to 1 ml and subsequent PCR amplification detection.
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