Article
Chemistry, Analytical
Weijie Wu, Xinyi Liu, Mengfei Shen, Lisong Shen, Xing Ke, Daxiang Cui, Wanwan Li
Summary: A novel multicolor quantum dot nanobead-based FLISA platform has been established for highly sensitive multiplexed detection of lung cancer tumor markers. The use of multicolor QDNBs as fluorescent labels enables high detection sensitivity and construction of multiplexed fluorescent biosensors, showing potential for clinical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Junwen Xu, Xiaowei Wei, Xiao Zhang, Zehan Cai, Yong Wei, Wei Liu, Jian Yang, Yawen Li, Xiaoxiao Cai, Tingting Bai, Zhirui Guo, Xiaojun Qu, Qingyi Zhu, Yefei Zhu
Summary: This study presented a microscopic imaging method for multiplexed detecting BC miRNAs using core-shell-shell bifunctional MFBs, incorporating CHA and TdT-mediated DNA polymerization. The strategy achieved sensitive and precise detection of miRNAs in clinical serum specimens, demonstrating consistency with qRT-PCR.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Nanoscience & Nanotechnology
Xin Ting Zheng, Yingying Zhong, Huan Enn Chu, Yong Yu, Yu Zhang, Jiah Shin Chin, David Lawrence Becker, Xiaodi Su, Xian Jun Loh
Summary: Effective wound care requires a comprehensive assessment of healing status. Researchers have developed a carbon dot-doped hydrogel sensor array for the simultaneous colorimetric detection of five wound biomarkers, enabling a holistic assessment of inflammation and infection.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Tae Won Nam, Yeonkyung Park, Yeon Sik Jung, Hyun Gyu Park
Summary: In this study, a polychromatic quantum dot array (PQDA) was developed for accurate quantification of multiple miRNAs. The PQDA, manufactured using advanced patterning techniques, showed a wide dynamic range and high specificity, enabling the identification of target miRNAs with high sensitivity.
Article
Food Science & Technology
Wenshuo Zhang, Hongda Zhong, Pingping Zhao, Aiguo Shen, Houbin Li, Xinghai Liu
Summary: Carbon quantum dots (CDs) show great potential in detecting food ingredients and contaminants due to their easy preparation, good biocompatibility, and adjustable modification. The design of probes for CDs can be categorized into three types, with the introduction of functional groups on the surface being a key factor. The intermolecular interactions of different target substances play a role in determining the choice of carbon source and synthesis method.
Article
Spectroscopy
Xieyin Li, Yuqian Zhang, Mian Wei, Manman Wang, Jing Wang, Guifu Zuo
Summary: A rod-like melem with high fluorescence quantum yield was prepared to enhance the chemiluminescence intensity, and a CL sensor based on this system was designed for the detection of reduced glutathione.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Yi-Chen Chen, Yu-Han Syu, Jhen-Yan Huang, Chun-Yi Lin, Yang-Hsiang Chan
Summary: We designed polymer dot-magnetic nanoparticle nanohybrids for signal enhancement in a test strip platform. The multicolor emissions of the Pdots enable multiplexing detection. We successfully detected two mycotoxins, aflatoxin B1 and zearalenone, with detection limits of 2.15 ng mL(-1) and 4.87 ng mL(-1), respectively.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Yan Zhang, Jinping Hu, Xiao-Yun Yang, Chun-yang Zhang
Summary: This method utilizes single-molecule detection and bidirectional strand displacement amplification to simultaneously detect UDG and hAAG with high sensitivity and good selectivity, enabling quantification of multiple DNA glycosylases at the single-cell level.
Article
Chemistry, Analytical
Mariana P. Sousa, Ana Margarida L. Piloto, Ana Claudia Pereira, Fernando C. Schmitt, Ruben Fernandes, Felismina T. C. Moreira
Summary: This study developed a CA 15-3 biosensor for ultrasensitive monitoring of breast cancer, which is a simple and sensitive method capable of detecting other molecules of interest in human serum matrices.
Article
Biochemical Research Methods
Divita Mathur, Meghna Thakur, Sebastian A. Diaz, Kimihiro Susumu, Michael H. Stewart, Eunkeu Oh, Scott A. Walper, Igor L. Medintz
Summary: Cell-free synthetic biology is a valuable tool for developing portable biosensors. By using a modular quantum dot-based reporter platform, it is possible to detect multiple analytes simultaneously.
ACS SYNTHETIC BIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Shuangyan Ding, Hailiang Hu, Xianglin Yue, Kaiwen Feng, Xiaoyu Gao, Qiuling Dong, Mingqi Yang, Ugur Tamer, Ganhui Huang, Jinsheng Zhang
Summary: A new detection method based on quantum dots was developed to detect Salmonella in milk, with a detection limit 10 times better than conventional sandwich ELISA. The biosensor showed good specificity for detecting Salmonella.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Chemistry, Analytical
Rongfang Li, Zhiwei Jing, Guomin Yang, Ruo Yuan, Fang Xin Hu, Shihong Chen
Summary: This study successfully applied nickel single-atom catalysts (Ni SACs) in the graphitic carbon nitride (g-C3N4)-H2O2 electrochemiluminescence (ECL) system and significantly enhanced its cathodic emission. The developed system was also able to detect hepatitis B virus (HBV) DNA with excellent performance.
ANALYTICAL CHEMISTRY
(2023)
Article
Spectroscopy
Yu-Ching Lin, Pei-Ying Lin, Shu-Ling Hsieh, Chen-Yu Tsai, Anil Kumar Patel, Reeta Rani Singhania, Rajendranath Kirankumar, Cheng-Di Dong, Chiu-Wen Chen, Shuchen Hsieh
Summary: This article describes an efficient and rapid detection method of formaldehyde by synthesizing APTES quantum dots, which react with formaldehyde to generate fluorescence quenching for detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Nanoscience & Nanotechnology
Hong-Rae Kim, Ji-Hong Bong, Jun-Hee Park, Zhiquan Song, Min-Jung Kang, Dong Hee Son, Jae-Chul Pyun
Summary: A hypersensitive photosensor based on CsPbBr3 quantum dots was developed for chemiluminescence immunoassays, showing high sensitivity and reduced trap states, making it feasible for detecting various diseases.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
Shengnan Fan, Xiaoqing Li, Fanghui Ma, Minghui Yang, Juan Su, Xiang Chen
Summary: This study reported a sensitive fluorescence assay for the accurate detection of LDH activity in serum using sulfur quantum dots (SQDs) and nicotinamide adenine dinucleotide (NAD(+)). The method achieved detection of LDH in the range from 500 to 40,000 U L-1 with a limit of detection of 262 U L-1. It has potential clinical applications.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Energy & Fuels
Yuhao Zhang, Hongling Ma, Xilin Shi, Hongwu Yin, Shengnan Zhang
Summary: This study focuses on the structure of China's salt mines and the design of horizontal salt cavern gas storage (HSCGS). By establishing a Yield-Dilatancy-Failure (YDF) model, the minimum pressure and casing shoe position have been determined, providing reference for the design of HSCGS.
ENERGY SOURCES PART A-RECOVERY UTILIZATION AND ENVIRONMENTAL EFFECTS
(2023)
Review
Food Science & Technology
Xiaoxue Zhu, Xin-Huai Zhao, Qiang Zhang, Na Zhang, Olugbenga P. Soladoye, Rotimi E. Aluko, Yuhao Zhang, Yu Fu
Summary: This article reviews the latest research progress on the relationship between celiac disease (CD) and gluten. It emphasizes the structure and function of gluten peptides related to CD, gluten detection methods, the effects of processing on gluten, and gluten-free diets. The limitations in current CD research are also discussed. This study facilitates a comprehensive understanding of CD and gluten, providing a theoretical reference for future research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Xilong Wang, Bei Le, Na Zhang, Kathrine H. Bak, Yuhao Zhang, Yu Fu
Summary: Collagen peptides from fish have excellent bioactive and functional properties, making them important functional ingredients in the food industry. However, the off-flavour in fish collagen peptides limits their application. Therefore, researching the removal of off-flavour compounds from fish collagen peptides is of great importance.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Hefei Liu, Yuan Qin, Hung-Yu Chen, Jiangbin Wu, Jiahui Ma, Zhonghao Du, Nan Wang, Jingyi Zou, Sen Lin, Xu Zhang, Yuhao Zhang, Han Wang
Summary: This paper reviews the progress of artificial neuronal devices based on emerging volatile switching materials, focusing on the demonstrated neuron models implemented in these devices and their utilization for computational and sensing applications. Furthermore, it discusses the inspirations from neuroscience and engineering methods to enhance the neuronal dynamics that are yet to be realized in artificial neuronal devices and networks towards achieving the full functionalities of biological neurons.
ADVANCED MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Kunran Xu, Huawei Zhang, Yishi Li, Yuhao Zhang, Rui Lai, Yi Liu
Summary: This article discusses the importance and challenges of tiny machine learning (TinyML), which executes AI workloads on resource and power strictly restricted systems. It introduces an extremely tiny backbone for constructing high efficiency CNN models for various visual tasks. Additionally, a specially designed neural co-processor (NCP) is interconnected with MCU to build an ultra-low power TinyML system, achieving record-breaking ultra-low power consumption of 160mW while implementing object detection and recognition at 30FPS.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS II-EXPRESS BRIEFS
(2023)
Article
Engineering, Electrical & Electronic
Boyan Wang, Ming Xiao, Zichen Zhang, Yifan Wang, Yuan Qin, Qihao Song, Guo-Quan Lu, Khai Ngo, Yuhao Zhang
Summary: Size optimization of Achip is crucial for accurate cost analysis and design of multichip modules, especially for high-cost WBG and UWBG power devices. This study presents a new electrothermal approach to optimize Achip for a given set of specifications, considering breakdown voltage, conduction current, and switching frequency. The approach takes into account conduction and switching losses, as well as heat dissipation in the chip and package. It provides guidelines for power module design and offers more accurate cost analysis.
IEEE TRANSACTIONS ON ELECTRON DEVICES
(2023)
Article
Engineering, Electrical & Electronic
Joseph P. Kozak, Qihao Song, Ruizhe Zhang, Yunwei Ma, Jingcun Liu, Qiang Li, Wataru Saito, Yuhao Zhang
Summary: This article presents a comparative study of the parametric shift and recovery of three mainstream GaN HEMTs in repetitive overvoltage switching. The study shows that the devices exhibit shifts in threshold voltage and saturation current during the switching process, and these shifts saturate in a short period of time. The recovery process is dominated by hole detrapping and through-gate removal, with the gate stack playing a significant role. The article also suggests effective methods for poststress recovery.
IEEE TRANSACTIONS ON POWER ELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Congyue Zhang, Xiaobo Dou, Lin Wang, Yunfei Dong, Yu Ji
Summary: This paper presents a unified distributed cooperative voltage control approach for grid-following (GFL) and grid-forming (GFM) distributed generators (DGs) in island microgrids. The approach employs a unified modeling method and a novel range-consensus-based distributed control algorithm. The proposed method improves the voltage regulation and anti-interference ability of the system, and its effectiveness is validated through simulation results and a hardware-in-the-loop test.
IEEE TRANSACTIONS ON POWER SYSTEMS
(2023)
Review
Physics, Applied
Ruizhe Zhang, Yuhao Zhang
Summary: This paper investigates avalanche and non-avalanche breakdown mechanisms in wide bandgap and ultra-wide bandgap devices and comparatively introduces various breakdown voltage characterization methods. Additionally, it discusses the device physics behind time- and frequency-dependent breakdown voltage and enabling device structures for avalanche breakdown, while identifying research gaps for understanding breakdown in wide bandgap and ultra-wide bandgap power devices.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2023)
Article
Mathematics, Applied
Yuhao Zhang, Haiyun Dong, Kun Wang
Summary: In this paper, we propose an unconditionally stable and decoupled identical-relation-preserving scheme for solving the incompressible Navier-Stokes equations with variable density. By introducing scalar auxiliary variables and converting the equations into an equivalent form, we construct a linear decoupled finite element scheme. The scheme is proven to preserve the mass, momentum, and energy identical relations and is efficient in numerical implementation. Numerical examples are provided to verify the correctness and efficiency of the proposed scheme, including an extension to a coupled nonlinear model with temperature.
COMPUTERS & MATHEMATICS WITH APPLICATIONS
(2023)
Article
Gastroenterology & Hepatology
Chao Sheng, Liping Sun, Zhangyan Lyu, Limin Li, Yuhao Zhang, Yu Zhang, Yacong Zhang, Hongji Dai, Yubei Huang, Fengju Song, Yuan Yuan, Kexin Chen
Summary: A modified ABC method was developed to improve gastric cancer screening performance in China, especially among Helicobacter pylori-infected but serum pepsinogen test-negative individuals. The study showed that this modified method effectively identified high-risk population for gastric cancer among the targeted individuals in China.
Article
Chemistry, Inorganic & Nuclear
Jing Sun, Xiongkai Tang, Jiaqi Tang, Yuhao Zhang, Zilin Li, Hui Chaolumen, Shuo Guo, Hui Shen
Summary: Little progress has been made in developing alternative bottom-up synthetic strategies for N-heterocyclic carbene (NHC)-stabilized gold nanoclusters, but this study presents a simple and straightforward approach using imidazolium salts instead of free carbenes or NHC-coordinated gold complexes as precursors. The researchers successfully synthesized an NHC-stabilized Au13Br4 cluster using a one-pot and one-step process involving chemical reduction. This work not only expands the Au13 library with a new NHC-ligated superatom, but also provides a facile and reasonable method to explore similar analogues.
INORGANIC CHEMISTRY
(2023)
Article
Nuclear Science & Technology
Haiqi Zhao, Daogang Lu, Yuhao Zhang, Xueyuan Zhang
Summary: This paper investigates the influence of different heat exchanger (DHX) layout schemes on the performance of a pool-type sodium-cooled fast reactor (SFR) through numerical simulations. The results show that installing DHXs in both cold and hot pools can achieve the long-term cooling stage of natural convection earlier and result in a more uniform temperature distribution in the hot pool. However, a local asymmetrical temperature distribution is observed in the cold pool.
PROGRESS IN NUCLEAR ENERGY
(2023)
Article
Nuclear Science & Technology
Yuhao Zhang, Xueyuan Zhang, Haiqi Zhao, Daogang Lu
Summary: The China Experimental Fast Reactor (CEFR) has a pool-type primary circuit. The sticking of the main circulating pump shaft in the secondary circuit is an important accident. To investigate this accident, the three-dimensional thermal-hydraulic phenomena in the sodium pool were simulated using a modular modeling and integrated coupling calculation method. The simulation results provided numerical reference for the safety design and assessment of CEFR.
PROGRESS IN NUCLEAR ENERGY
(2023)
Article
Chemistry, Physical
Mengting Jin, Yanhao Wang, Mengyue Gu, Xuewen Zhao, Rongzheng Zhao, Yuhao Zhang, Yonghong Cheng, Jinying Zhang
Summary: This study successfully controlled the growth of layered violet phosphorus along a specific direction with the assistance of tin, resulting in needle-shaped phosphorus with enhanced photocatalytic degradation ability.
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)