Article
Biophysics
Kenichi Nagase, Akari Okada, Junnosuke Matsuda, Daiju Ichikawa, Yutaka Hattori, Hideko Kanazawa
Summary: In this study, a thermoresponsive cationic block copolymer brush-grafted beads were developed as packing materials for ADSC separation columns. These columns can adsorb ADSCs at 37 degrees C and elute them at 4 degrees C, while other cells are not adsorbed. This separation column can be used to isolate ADSCs without cell surface modification, while maintaining cell activity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Polymer Science
Kokila Thirupathi, Thi Tuong Vy Phan, Madhappan Santhamoorthy, Vanaraj Ramkumar, Seong-Cheol Kim
Summary: The study developed a temperature and pH-responsive poly(N-isopropyl acrylamide)-co-poly(acrylamide) (PNIPAM-co-PAAm) using free radical polymerization. The resulting PNIPAm-co-PAAm-Mela HG system showed temperature-responsive phase transition characteristics and efficient drug release under pH and temperature stimuli. Additionally, the synthesized PNIPAm-co-PAAm-Mela HG exhibited biocompatibility on a human liver cancer cell line.
Article
Polymer Science
Chia-Hsin Ko, Cristiane Henschel, Geethu P. Meledam, Martin A. Schroer, Peter Mueller-Buschbaum, Andre Laschewsky, Christine M. Papadakis
Summary: The temperature-dependent phase behavior and self-assembly behavior of a thermoresponsive amphiphilic diblock copolymer in aqueous solution were studied, revealing a lower critical solution temperature (LCST) behavior at 31.1 degrees Celsius and the formation of different structures of micelles.
Article
Polymer Science
Adil Usman, Cheng Zhang, Jiacheng Zhao, Hui Peng, Nyoman D. Kurniawan, Changkui Fu, David J. T. Hill, Andrew K. Whittaker
Summary: A series of terpolymers with thermoresponsive properties were synthesized, and it was found that above the LCST, the F-19 MRI imaging intensity decreased due to enhanced dipolar interactions of the F-19 spins. By incorporating a hydrophobic model drug through an acid cleavable hydrazone linkage, a thermo- and pH-responsive F-19 MRI agent was designed.
Article
Polymer Science
Jun He, Dongni Lin, Ying Chen, Li Zhang, Jianbo Tan
Summary: A new method has been developed in this study to prepare PNIPAM-based block copolymer nanoparticles with different morphologies through aqueous photoinitiated polymerization-induced self-assembly, and it was found that the reaction temperature plays a crucial role in both morphology and polymerization kinetics of the nanoparticles.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Inyoung Choi, Saeeun Jang, Seunggyeom Jung, Seohyun Woo, Jinyoung Kim, Cheol Bak, Yongmin Lee, Sukho Park
Summary: This paper presents a 4D printed smart soft carrier with a hemispherical hollow and openable lid. The carrier is made of thermo-responsive hydrogels and utilizes superparamagnetic iron oxide nanoparticles for magnetic control. It can transport cargo underwater and handle living marine organisms. The flexibility of 4D printing allows for customization of the carrier's size, making it adaptable for various objects.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Physical
Yongfang Yao, Chetan Patel, Rohit L. Vekariya, Shin-ichi Yusa, Chetan B. Sangani, Yongtao Duan, Sadafara Pillai, Hiren Patel, Nadavala Siva Kumar, Mehul Khimani
Summary: Stimuli-responsive di-block copolymers were synthesized, with the LCST of PNIPAM being independent of molecular weight and no LCST behavior observed for PBVIB58 in aqueous media. The addition of sodium chloride can bring PBVIB58's LCST to room temperature. The cloud point temperature of both block copolymers increases with the degree of polymerization of PBVIB.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Polymer Science
Erigene Bakangura, David Fournier, Fanny Coumes, Patrice Woisel, Daniel Grande, Benjamin Le Droumaguet
Summary: Functional nanoporous polymeric materials were prepared from novel PS-b-PEO diblock copolymer precursors containing reversible boronate ester junction. The generation of oriented cylindrical nanopores was achieved by selective etching of PEO under mild acidic conditions.
Article
Biochemistry & Molecular Biology
Lais Ramos Monteiro Lima, Everton Lucas de Lima Ramos, Maria Francilene Souza Silva, Fabio de Oliveira Silva Ribeiro, Jeanlex S. Sousa, Claudia Pessoa, Durcilene Alves Silva, Judith P. A. Feitosa, Haroldo C. B. Paula, Regina Celia Monteiro de Paula
Summary: In this study, aminated poly(N-isopropylacrylamide) was successfully grafted onto oxidized galactomannan polysaccharide from Delonix regia via Schiff base reaction. The self-organizing ability of the obtained nanoparticle copolymers was investigated, showing promising potential for drug delivery with good cell viability and transition temperature close to human body temperature. The use of free aldehyde groups in the oxidized polysaccharide for pro-drug formation with substances possessing NH2 groups was also highlighted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Shu Wang, Purushottam Poudel, Felix H. Schacher, Leonid I. Kaberov
Summary: In this work, a method for synthesizing temperature and light-responsive copolymers by introducing azobenzene fragments in the side chain of poly(2-oxazoline)s is proposed. The obtained copolymers exhibited thermo-responsive behavior and reversible isomerization of azobenzene units under UV and visible light exposure. The presence of nanoparticles in the aqueous solutions of the copolymers was confirmed, and the size of these nanoparticles changed in response to UV irradiation.
Article
Polymer Science
Lu Lian, Qingqing Wang, Fujin Duan, Youliang Zhao
Summary: Rational macromolecular design can enable polymers to exhibit thermoresponsive behaviors according to specific requirements. By synthesizing poly(amido thioether)s with different side groups, it is possible to achieve single or dual phase transitions that are concentration-independent, exhibit good thermal stability, and show both UCST and LCST behaviors.
Review
Chemistry, Multidisciplinary
Tiefan Huang, Zhixin Su, Kun Hou, Jianxian Zeng, Hu Zhou, Lin Zhang, Suzana P. Nunes
Summary: This review summarizes the important developments and achievements in stimuli-responsive membranes, including the commonly utilized stimuli and strategies to prepare them. It discusses the control of membrane pore structure and surface properties, as well as the smart applications for separations. The remaining challenges and future prospects in this field are also reviewed.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Polymer Science
Shuqi Dong, Li Liu, Hanying Zhao
Summary: In this study, oxidation-responsive amphiphilic block copolymers were synthesized and self-assemblies with different morphologies were achieved by adjusting the hydrophobic block length. Hybrid polymersomes with Cu2+-cross-linked membrane were fabricated, featuring a responsive property to competitive ligands, thanks to the metal-ligand interaction.
Article
Polymer Science
Chia-Hsin Ko, Cristiane Henschel, Geethu P. Meledam, Martin A. Schroer, Renjun Guo, Luka Gaetani, Peter Mueller-Buschbaum, Andre Laschewsky, Christine M. Papadakis
Summary: The self-assembly of the thermoresponsive amphiphilic diblock copolymer PMMA(21)-b-PNIPAM(283) in various water/methanol mixtures was studied. It was found that the solvent composition significantly affected the internal morphology of micelles and the conformation of dissolved chains.
Article
Materials Science, Multidisciplinary
Sharmita Bera, Juthi Pal, Satyagopal Sahoo, Dibakar Dhara
Summary: It is crucial to replace the traditional toluene chlorination process for benzaldehyde production with a more environmentally friendly method. In this study, polymer-conjugated magnetic nanoparticles were developed as green catalysts. These nanoparticles showed high catalytic activity in the synthesis of benzaldehyde using styrene oxidation reaction at room temperature in water. The catalysts could be easily recovered and reused without significant loss in activity.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Engineering, Environmental
Asya Drenkova-Tuhtan, Michael Schneider, Matthias Franzreb, Carsten Meyer, Carsten Gellermann, Gerhard Sextl, Karl Mandel, Heidrun Steinmetz
Article
Biochemical Research Methods
Moritz Ebeler, Florian Pilgram, Kai Wolz, Gunnar Grim, Matthias Franzreb
BIOTECHNOLOGY JOURNAL
(2018)
Article
Chemistry, Multidisciplinary
J. Huebner, R. Heinzler, C. Arlt, S. Hohmann, G. Brenner-Weiss, M. Franzreb
REACTION CHEMISTRY & ENGINEERING
(2017)
Article
Biotechnology & Applied Microbiology
Barbara Schmieg, Adrian Schimek, Matthias Franzreb
ENGINEERING IN LIFE SCIENCES
(2018)
Article
Biochemical Research Methods
Moritz Ebeler, Ola Lind, Nils Norrman, Ronnie Palmgren, Matthias Franzreb
Article
Polymer Science
Gowthamy Venkidasubramonian, Domenic Kratzer, Vanessa Trouillet, Nicolas Zydziak, Matthias Franzreb, Leonie Barner, Joerg Lahann
Article
Engineering, Biomedical
Lisa Rodling, Esther Magano Volz, Annamarija Raic, Katharina Braendle, Matthias Franzreb, Cornelia Lee-Thedieck
ADVANCED HEALTHCARE MATERIALS
(2018)
Article
Engineering, Chemical
Ellen Hack, Dominik Hummer, Matthias Franzreb
SEPARATION AND PURIFICATION TECHNOLOGY
(2019)
Article
Chemistry, Applied
Raphael Heinzler, Thomas Fischoeder, Lothar Elling, Matthias Franzreb
ADVANCED SYNTHESIS & CATALYSIS
(2019)
Article
Biochemistry & Molecular Biology
Thomas Fischoeder, Samanta Cajic, Valerian Grote, Raphael Heinzler, Udo Reichl, Matthias Franzreb, Erdmann Rapp, Lothar Elling
Article
Chemistry, Multidisciplinary
Raphael Greifenstein, Tim Ballweg, Tawheed Hashem, Eric Gottwald, David Achauer, Frank Kirschhoefer, Michael Nusser, Gerald Brenner-Weiss, Elaheh Sedghamiz, Wolfgang Wenzel, Esther Mittmann, Kersten S. Rabe, Christof M. Niemeyer, Matthias Franzreb, Christof Woell
Summary: We have demonstrated a MOF-based continuous flow enzyme reactor system that allows efficient and stable catalysis in organic solvents. The stability and productivity of the enzyme were significantly improved under aqueous conditions, without the need for additional functionalization, making the fabrication process time- and cost-efficient using label-free enzymes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Engineering, Chemical
Carolin Prechtl, Manfred Kraut, Matthias Franzreb, Gerald Brenner-Weiss, Roland Dittmeyer
CHEMICAL ENGINEERING & TECHNOLOGY
(2017)
Article
Nanoscience & Nanotechnology
Benedikt Ketterer, Huey Wen Ooi, Dominik Brekel, Vanessa Trouillet, Leonie Barner, Matthias Franzreb, Christopher Barner-Kowollik
ACS APPLIED MATERIALS & INTERFACES
(2018)
Article
Biotechnology & Applied Microbiology
Raphael Heinzler, Jonas Huebner, Thomas Fischoeder, Lothar Elling, Matthias Franzreb
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2018)