Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 406, Issue 23, Pages 5695-5702Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-014-7812-x
Keywords
Bioavailability; Bioreporter; Bisphenol A; Endocrine-disrupting compounds; Saccharomyces cerevisiae; Thermal paper
Funding
- Academy of Finland
- Finnish Doctoral Programme in Environmental Science and Technology
Ask authors/readers for more resources
Bioluminescent Saccharomyces cerevisiae yeast-based bioreporters were used to monitor bisphenol A and other estrogenic chemicals in thermal paper samples collected mainly from Finland on two occasions in 2010/2011, and 2013. The bisphenol A-targeted (BPA-R) and the human oestrogen receptor (hER alpha) bioreporters were applied to analyse both non-treated and extracted paper samples. Bisphenol A was readily bioavailable to the yeast bioreporters on the non-treated paper samples without any pre-treatment. Detected concentrations ranged from a detection limit of 9-142 mu g/g to over 20 mg/g of bisphenol A equivalents in the thermal papers. Low bisphenol A like activities were detected in many samples, and were considered to be caused by residual bisphenol A or other types of bisphenols, such as bisphenol S. Most of the thermal paper samples were toxic to the yeast bioreporters. The toxicity did not, however, depend on the bisphenol A concentration of the samples. The yeast bioreporters were demonstrated to be a robust and cost-efficient method to monitor thermal paper samples for their bisphenol A content and estrogenicity. Thermal paper was considered as a potential BPA source for both human exposure and environmental emission.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available