Article
Biochemical Research Methods
Tianpei Cai, Yanqiang Zhou, Huachun Liu, Jianmin Li, Xiaoxiao Wang, Shanwen Zhao, Bolin Gong
Summary: Monodisperse RAM-MIPs were synthesized for solid-phase extraction of SAR residues from egg samples, showing superior enrichment and selectivity compared to traditional MIPs. The SAR imprinting factor was 6.05 and the selectivity coefficient between SAR and other fluoroquinolones was 1.86-2.64. The limit of quantitation for SAR was 4.23 ng g -1 with a mean SAR recovery from spiked egg samples of 94.0-101.3%. Intra-day and inter-day relative standard deviations were 1.1-9% and 1.5-3.3%, respectively.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Chemistry, Analytical
Xiu Liu, Junli Pu, Jianming Li, Bolin Gong
Summary: A novel restricted-access polymer was prepared and used for the enrichment of fluoroquinolones in untreated egg samples. The polymer exhibited good adsorption performance, selective binding, and the ability to eliminate matrix interference.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Analytical
Luxiu Li, Ya Cui, Lingling Ren, Chunyang Li, Yehao Liu, Zhongxiu Jin
Summary: A simple and efficient dispersive solid-phase microextraction method based on magnetic dummy molecularly imprinted polymer nanoparticles was developed for the extraction of five phthalate monoesters from human urine samples. The prepared nanoparticles showed high selectivity, good adsorption capacity, excellent reusability, and fast adsorption rates. Furthermore, the method demonstrated good linearity and recovery rates for all five phthalate monoesters in human urine samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Polymer Science
Renyuan Song, Jiawei Xie, Xiaofeng Yu, Jinlong Ge, Muxin Liu, Liping Guo
Summary: Molecularly imprinted polymer microspheres with porous structures were prepared and used for the solid-phase extraction of drug molecules in urine samples. The results showed that the method had outstanding selectivity and template recognition effect, which could be applied in drug separation and functional materials science fields.
Article
Chemistry, Analytical
Xiaolei Zhao, Lei Lu, Mengzhen Zhu, Huilin Liu, Jinxing He, Fuping Zheng
Summary: Highly hydrophilic magnetic molecularly imprinted polymers were prepared for the detection of trace levels of sulfonamides in animal-derived samples, showing excellent specific adsorption properties for the target template compound. The method, with good linear performance and high recoveries in spiked samples, avoids the use of organic solvents and simplifies the pretreatment process. This approach holds great potential for rapid detection of drug residues.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Chemistry, Analytical
Xinyu Wang, Yan Feng, Haiyan Chen, Yan Qi, Jianrong Yang, Shuang Cong, Yongxin She, Xiaolin Cao
Summary: The study prepared dummy template molecularly imprinted polymers using precipitation polymerization method and characterized the obtained polymers. The polymers showed high adsorption capacity, efficiency and specific recognition ability towards N-nitrosamines. A solid phase extraction process based on the polymers coupled with high performance liquid chromatography-tandem mass spectrometry was established and demonstrated good linearity, low limits of detection and quantification, as well as satisfactory recoveries. The method provided a convenient way to enrich and detect N-nitrosamines in complex food matrix.
MICROCHEMICAL JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Federica Pessagno, Matthew Blair, Mark J. Muldoon, Panagiotis Manesiotis
Summary: In this study, organocatalyst-selective molecularly imprinted polymers were successfully prepared using strong binding affinity. These polymers demonstrated exceptional binding for the organocatalyst targets and were able to reversibly capture the desired compounds from reaction mixtures. Rapid and straightforward solid-phase extraction protocols allowed for efficient catalyst recovery and reuse.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Sarah H. Megahed, Mohammad Abdel-Halim, Amr Hefnawy, Heba Handoussa, Boris Mizaikoff, Nesrine A. El Gohary
Summary: This study used molecularly imprinted polymers (MIPs) for selective extraction of quinic acid (QA) from coffee bean extract. Computational modeling and equilibrium rebinding studies were performed to optimize the preparation of MIP C, which showed better binding performance than other MIPs tested. The applied molecularly imprinted solid-phase extraction (MISPE) using MIP C was able to selectively extract QA from aqueous coffee extract, with reduced interference from other components.
Article
Biochemical Research Methods
Siyu Guo, Shanshan Wu, Shanwen Zhao, Xiaoxiao Wang, Tianpei Cai, Jianmin li, Bolin Gong
Summary: Unique restricted access media-magnetic molecularly imprinted polymers (RAM-MMIPs) were prepared and used for the extraction of florfenicol (FF) from fetal bovine serum samples. The optimized conditions resulted in materials with uniform imprinted layer, acceptable adsorption amounts, rapid binding kinetics, and satisfactory selectivity. The method showed advantages of simple, fast, and efficient operation, with relatively small amount of RAM-MMIPs adsorbent used.
Article
Nanoscience & Nanotechnology
Alessandra Maria Bossi, Alessio Bucciarelli, Devid Maniglio
Summary: Nanosized biomimetics prepared by molecular imprinting are showing potential as plastic antibodies in medicine for cell imaging and targeted therapies. Utilizing natural polymer silk fibroin to synthesize biocompatible MIP SF-NPs demonstrates high affinity recognition sites and biocompatibility.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Chemistry, Analytical
Foad Mashayekhi Suzaei, Alex D. Batista, Boris Mizaikoff, Sima Rahimi, Seyed Mosayeb Daryanavard, Mohamed Abdel-Rehim
Summary: In recent years, there have been significant efforts to develop methods for early diagnosis, treatment, and monitoring of cancers using molecularly imprinted technology. These methods have demonstrated high selectivity, accuracy, and low limits of detection, making them important tools for early diagnosis and treatment monitoring.
Article
Chemistry, Analytical
Mingxin Xu, Jie Li, Qingyun Chang, Xiaohuan Zang, Shuaihua Zhang, Chun Wang, Zhi Wang
Summary: A molecularly imprinted triazine-based conjugated microporous polymer composite was developed for the solid-phase extraction (SPE) of three phenolic endocrine disrupting chemicals in beverages. The method involved derivatization and detection by gas chromatography-electron capture detector. Under optimized conditions, the limits of detection of the analytes ranged from 0.12 to 1.20 μg L-1 and the linear response range was 0.40-50.0 μg L-1. The method showed good recoveries and potential for the monitoring of trace phenolic endocrine disrupting chemicals in real beverage samples.
MICROCHEMICAL JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Guangli Zhao, Yue Zhang, Dani Sun, Shili Yan, Yuhao Wen, Yixiao Wang, Guisheng Li, Huitao Liu, Jinhua Li, Zhihua Song
Summary: The abuse and residues of antibiotics have a significant impact on the environment and organisms, making their determination crucial. Molecularly imprinted polymers (MIPs), prepared via molecular imprinting technology (MIT), have found wide applications in the analytical detection of antibiotics. This review discusses the recent advances in MIPs for antibiotic residue analysis.
Article
Engineering, Environmental
Shikha Bhogal, Irshad Mohiuddin, Ki-Hyun Kim, Ashok Kumar Malik, Kuldeep Kaur
Summary: A highly effective method using restricted access medium magnetic molecularly imprinted polymer (RAM-MMIP) for selective identification and isolation of phthalates (PTHs) has been established. The RAM-MMIP was synthesized using Fe3O4@SiO2 as support material, diethyl phthalate and dicyclohexyl phthalate as dual dummy templates, and (3-glycidyloxypropyl)trimethoxysilane as the silane coupling agent. The RAM-MMIP showed selectivity for PTHs and recyclability for multiple cycles, with successful application for extraction of PTHs from plastic packaged foods.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yue Wang, Yuan Xu, Ruixia Gao, Xuemeng Tian, Jake Heinlein, Sameer Hussain, Lisa D. Pfefferle, Xiaoyi Chen, Xiaojing Zhang, Yi Hao
Summary: This study develops lightweight hollow double-layer hybrid magnetic molecularly imprinted polymers (HD-MMIPs) using green and sustainable chemistry, which improved the adsorption capacity and the rebinding rate of tetracycline (TC) compared to traditional surface molecularly imprinted polymers (SMIPs). The Fe3O4 nanoparticles embedded in the HD-MMIPs significantly facilitated the separation process. The HD-MMIPs also showed potential in monitoring and controlling TC contamination in real samples.
Review
Chemistry, Analytical
Jaime Millan-Santiago, Rafael Lucena, Soledad Cardenas
Summary: Lignocellulosic materials have emerged as a sustainable alternative in microextraction techniques, adhering to principles of Green Analytical Chemistry. Their porosity, shape, and rigidity allow for use in ambient ionization mass spectrometry techniques, particularly in wooden-tip electrospray ionization mass spectrometry. They can be used for direct analysis of complex samples, with the potential for surface modification to enhance interaction with target compounds.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Analytical
Francisco Antonio Casado-Carmona, Juan Manuel Jimenez-soto, Rafael Lucena, Soledad Cardenas
Summary: Sampling at multiple locations is crucial for providing complete and representative information due to the spatial heterogeneity of environmental systems. A portable, simple, and low-cost device has been developed for the simultaneous on-site extraction of multiple environmental water samples, demonstrating potential applications for atrazine and simazine isolation and preconcentration in environmental water analysis.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biochemical Research Methods
Beatriz Fresco-Cala, Angela Lopez-Lorente, Alex D. Batista, Mehmet Dinc, Joachim Bansmann, R. Juergen Behm, Soledad Cardenas, Boris Mizaikoff
Summary: The development of synthetic particles that mimic real viruses is essential for the advancement of molecularly imprinted polymer-based sorbent materials. In this study, gold nanoparticles were synthesized and modified to serve as surrogates for adenovirus type 5. The successful attachment of the most abundant protein of the virus, hexon protein, to the surface of the nanoparticles was achieved through both non-covalent and covalent methods. This research demonstrates the importance of developing synthetic particles that closely resemble viruses for the development of advanced sorbent materials.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Carmina Vejar-Vivar, Jaime Millan-Santiago, Claudia Mardones, Rafael Lucena, Soledad Cardenas
Summary: This study evaluates polydopamine inner wall-coated hypodermic needles as microextraction devices and electrospray ionization emitters for determining illicit drugs in oral fluid samples.
Article
Biochemical Research Methods
Inmaculada Lopez-Ruiz, Guillermo Lasarte-Aragones, Rafael Lucena, Soledad Cardenas
Summary: Paper-based sorptive phases have been developed with deep eutectic solvents (DES) as coating for the isolation and analysis of selected triazine herbicides in environmental water samples. The method demonstrates good sensitivity, accuracy, and precision, with wide applicability.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Saloua Hammadi, Jaime Millan-Santiago, Latifa Latrous El Atarche, Rafael Lucena, Soledad Cardenas
Summary: This article describes the use of wooden tips as substrates under a hybrid microextraction format, which combines the extraction capacities of wood and an organic solvent. 1-octanol is selected as the solvent and the extraction capabilities of octanol-supported wooden tips are studied using non-steroidal anti-inflammatory drugs as model analytes. The impact of wood matrix compounds on determining the analytes by mass spectrometry is also studied.
MICROCHEMICAL JOURNAL
(2023)
Article
Biochemical Research Methods
Carlos Calero-Canuelo, Francisco Antonio Casado-Carmona, Rafael Lucena, Soledad Cardenas
Summary: This article describes the synthesis of mixed-mode cationic exchange (MCX) tapes as sorptive phases in bioanalysis, and it faces the determination of methadone and tramadol in saliva as the model analytical problem. The tapes are synthesized using aluminum foil as a substrate, which is subsequently covered with double-sided adhesive tape where the MCX particles finally adhere. Under the optimum conditions and using direct infusion mass spectrometry as the instrumental technique, detection limits as low as 3.3 μg·L-1 were obtained. The precision and accuracy of the method were also evaluated and found to be satisfactory.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Engineering, Environmental
Francisco Antonio Casado-Carmona, Rafael Lucena, Soledad Cardenas
Summary: This article presents a new device based on open-source technologies for on-site extraction of isoflavones from environmental waters. The device is operated by an Arduino microcontroller and integrates sensors to provide real-time information. The extraction unit utilizes a planar sorptive phase and the samples are analyzed in the lab using liquid chromatography coupled with mass spectrometry. The method shows good precision and accuracy, and the importance of isotopically labeled compounds for normalizing extraction variables is discussed.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Physical
Jose Estrada-Pomares, Susana Ramos-Terron, Guillermo Lasarte-Aragones, Rafael Lucena, Soledad Cardenas, Daily Rodriguez-Padron, Rafael Luque, Gustavo de Miguel
Summary: This study presents the synthesis and characterization of two bismuth-based halide perovskites. Cs2AgBiBr6 exhibits better absorption in the visible region compared to Cs3Bi2Br9. Both materials can be used as photocatalysts for the oxidation of vanillyl alcohol.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Review
Environmental Sciences
Jaime Millan-Santiago, Francisco Antonio Casado-Carmona, Rafael Lucena, Soledad Cardenas
Summary: Polymeric nanocomposites are widely used as sorbents for extracting pollutants from environmental waters before their final instrumental analysis. These materials are highly versatile and can be adapted to a given analytical problem by selecting the appropriate polymer/nanomaterial combination. The adaptability is enhanced by their easy preparation in the laboratory and the availability of different formats (particles, membranes, monoliths, or fibers). This article provides a general overview of the potential of polymeric nanocomposites, with a focus on the practical aspects of synthesis and microextraction techniques. It aims to inspire researchers by showcasing the almost endless possibilities of these materials in sample preparation and highlighting the main trends in the near future.
CURRENT OPINION IN ENVIRONMENTAL SCIENCE & HEALTH
(2022)
