Article
Green & Sustainable Science & Technology
Fatima C. Teixeira, Antonio P. S. Teixeira, C. M. Rangel
Summary: In this study, new doped Nafion membranes were prepared by casting with AzBPs as dopants. The proton conduction properties of the modified membranes were significantly improved compared to the reference Nafion membrane. The membrane with AzBP1 as dopant showed the best proton conductivity.
Article
Chemistry, Physical
Fatima C. Teixeira, Ana de Sa, Antonio P. S. Teixeira, V. M. Ortiz-Martinez, A. Ortiz, I Ortiz, C. M. Rangel
Summary: The study focused on the development of new Nafion membranes by incorporating aryl- or azaheteroaromatic bisphosphonate compounds as dopants, resulting in enhanced proton conductivity properties compared to commercial Nafion membranes. These doped membranes showed improved performance in fuel cells at different temperatures, with a maximum power output of around 383 mW cm(-2) at 70 degrees C. The membranes also demonstrated potential advantages in restricting gas crossover, as indicated by higher open circuit potentials compared to Nafion membranes under the same conditions.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Engineering, Environmental
Y. Prykhodko, K. Fatyeyeva, L. Hespel, S. Marais
Summary: Over 50% of energy is currently produced by burning non-renewable fossil fuels, leading to the release of greenhouse gases and environmental pollution. As a result, research on renewable energy sources, storage, and energy transformation devices has become increasingly important in recent years. Fuel cells, particularly proton exchange membrane fuel cells, are considered a promising energy device with ongoing developments in membrane technology.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Environmental Sciences
Asif Jamil, Sikander Rafiq, Tanveer Iqbal, Hafiza Aroosa Aslam Khan, Haris Mahmood Khan, Babar Azeem, M. Z. Mustafa, Abdulkader S. Hanbazazah
Summary: Fuel cells are environmentally friendly technology with high efficiency and economic advantages. Proton exchange membranes, especially for hydrogen fuel cells, have great potential but face challenges in terms of cost and degradation of proton exchange capacity over time.
Review
Chemistry, Physical
Anuj Kumar, Shumaila Ibraheem, Sajjad Ali, T. Maiyalagan, Muhammad Sufyan Javed, Ram K. Gupta, Ali Saad, Ghulam Yasin
Summary: Due to the hydrophobic nature of the fluorocarbon backbone, Nafion membranes are preferred for high H+ conductivity. However, they are limited by a higher price, pH splitting, and bio-fouling, leading researchers to search for better alternatives. Conducting polymers like polyaniline and polypyrrol can be used as electrolyte membranes for fuel cells, and their conductivity can be enhanced through doping techniques. This review provides a detailed discussion on these conducting polymers and their applications, particularly in composite membranes, and evaluates their effects on methanol crossover, H+-conductivity, gas diffusion, and thermal stability for practical DMFC applications.
SURFACES AND INTERFACES
(2022)
Review
Chemistry, Physical
Shahbaz Ahmad, Tahir Nawaz, Asghar Ali, Mehmet Fatih Orhan, Ayesha Samreen, Arunachala M. Kannan
Summary: Proton exchange membrane fuel cells are considered efficient and clean energy conversion devices, but their high manufacturing cost remains a major barrier to their general acceptance and commercialization. Lowering the cost of the electrolyte and catalyst is the main strategy for reducing fuel cell cost. The development of low-cost and high-performance electrolyte membranes is a top priority.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Polymer Science
Tushar Kanti Maiti, Jitendra Singh, Subrata Kumar Maiti, Jagannath Majhi, Arihant Ahuja, Manjinder Singh, Anasuya Bandyopadhyay, Gaurav Manik, Sujay Chattopadhyay
Summary: In this study, the introduction of sulfonic acid functionalized graphene oxide (SGO) into Perfluorosulfonic acid (PFSA) membranes improved the glass transition temperature (Tg), mechanical properties, proton conductivity, and single-cell performance. The loading of SGO increased the Tg and modulus of PFSA composite membranes, leading to enhanced proton conductivity and fuel cell performance.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Liyu Zhu, Yucheng Li, Peng Ye, Jingyang Zhao, Jing Liu, Jiandu Lei, Luying Wang, Ruisheng Xue
Summary: This article presents an ultra-stable and highly proton conductive self-healing proton exchange membrane made by complexation between Nafion and poly(vinyl alcohol) (PVA), followed by incorporation of sodium lignosulfonate (SLS) intercalation-modified graphene oxide (GO) and post-modification with 4-formylbenzoic acid (FBA). Compared to recast Nafion, the composite membranes exhibit improved mechanical properties and higher proton conductivity. Moreover, the incorporated PVA gives the membranes superior self-healing capabilities. This study opens up new possibilities for the development of reliable and durable proton exchange membranes for fuel cells.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Review
Polymer Science
Oleg N. Primachenko, Elena A. Marinenko, Alexey S. Odinokov, Svetlana V. Kononova, Yuri V. Kulvelis, Vasily T. Lebedev
Summary: This review focuses on key problems in the development of modern proton-conducting membranes for hydrogen power, particularly for use in fuel cells at high temperatures without catalyst poisoning. It discusses new synthesis approaches and the modification of membranes with chemically stable nanoparticles. Advanced structural methods play a crucial role in understanding molecular ordering and the formation of conducting channels in membranes, with neutron scattering being highlighted as a powerful tool for analysis of ionomers and nanoscale structures in membrane materials. Integration of novel methods such as emulsion polymerization and the use of nanodiamonds and other nanoparticles in polymer matrices shows promise for creating new generations of membrane materials with enhanced functional properties.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Chemistry, Physical
Fatemeh Mahdi, Leila Naji, Alireza Rahmanian
Summary: This study presents a fabrication method for a membrane electrode assembly (MEA) with low Pt loading based on a Nafion/sulfonated graphene oxide (SGO) nanocomposite membrane. The fabricated MEA showed improved physicochemical and electrochemical characteristics compared to MEAs based on pure Nafion or Nafion/GO membranes. The best Nafion/SGO MEA exhibited higher water uptake, electrochemical surface area, and proton conductivity, as well as high durability in acidic solutions.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Physical
Hyunseung Lee, Hongdae Seo, Seong Ku Kim, Insung Bae
Summary: The aligned nanostructure of perfluorinated polymer electrolytes, achieved through capillary force lithography, enables increased proton conductivity. A hierarchical structure is realized through soft lithography, allowing control over the structures of proton-transporting channels. The line-patterned membranes show enhanced proton conductivities, as confirmed by electrochemical impedance analysis. Moreover, an increased interfacial contact area improves the power generation efficiency of the membrane-electrode assembly in proton-exchange membrane fuel cells.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Energy & Fuels
Seung-Young Choi, Muhammad Mara Ikhsan, Kyeong Sik Jin, Dirk Henkensmeier
Summary: The physicochemical properties of PFSA polymers are closely related to their nanostructure, but the accurate morphology at the nanoscale is still controversial. This study focuses on the crystalline domain and ionic domain of two PFSA membranes using small-angle X-ray scattering. The hydration process significantly alters both domains, and the behavior depends on the side-chain length of the membranes.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Article
Chemistry, Physical
Shaoxiong Zhai, Zhongrui Lu, Yuna Ai, Xiaoyang Jia, Yumeng Yang, Xin Liu, Miao Tian, Xingming Bian, Jun Lin, Shaojian He
Summary: This study successfully improved the performance of proton exchange membranes under low humidity by synthesizing phospho-tungstic acid functionalized covalent organic framework nanohybrids, further advancing the development of PEM fuel cells.
JOURNAL OF POWER SOURCES
(2023)
Review
Biochemistry & Molecular Biology
Jonathan Ramirez-Nava, Mariana Martinez-Castrejon, Rocio Lley Garcia-Mesino, Jazmin Alaide Lopez-Diaz, Oscar Talavera-Mendoza, Alicia Sarmiento-Villagrana, Fernando Rojano, Giovanni Hernandez-Flores
Summary: Microbial fuel cells (MFCs) are electrochemical devices focused on bioenergy generation and organic matter removal using membranes as separators. There are various membranes or separators available for MFCs, including NF-117 membrane, but one of the challenges is the high cost. Research efforts should be increased to develop more economic membranes with favorable properties for satisfactory cell performance.
Article
Chemistry, Physical
Lei Liu, Yijing Xing, Zhiyong Fu, Yifan Li, Zhuoqun Li, Haibin Li
Summary: In this study, a novel approach for preparing membrane electrode assemblies (MEAs) is proposed to optimize the interface combination and durability of proton exchange membrane (PEM) and catalyst layers (CLs). This approach combines a wet-contact interface design strategy and expanded polytetrafluoroethylene (ePTFE) reinforcing technology. The MEAs prepared using the wet-contact process show significantly reduced interfacial resistance and charge-transfer resistance, improved electrochemical surface area, and superior power performance compared to conventional MEAs. The insertion of ePTFE reinforcement skeletons into the PFSA membrane also reduces hydrogen crossover and mechanical degradation.
JOURNAL OF POWER SOURCES
(2023)
Article
Materials Science, Textiles
Sangeetha Dharmalingam, Omkumar Meenakshisundaram, Vijayakumar Elumalai, Rajendra S. Boopathy
Summary: This work aimed to develop a natural fiber-reinforced epoxy composite with enhanced compatibility by amino silane treatment of Luffa fiber. The amine modification of the fiber surface was confirmed through FTIR and SEM. The amine-functionalized composites showed improved thermal, mechanical, and morphological properties compared to plain epoxy composites.
JOURNAL OF NATURAL FIBERS
(2021)
Article
Biotechnology & Applied Microbiology
Vaidhegi Kugarajah, Moogambigai Sugumar, Sangeetha Dharmalingam
ENZYME AND MICROBIAL TECHNOLOGY
(2020)
Article
Engineering, Environmental
Vaidhegi Kugarajah, Sangeetha Dharmalingam
CHEMICAL ENGINEERING JOURNAL
(2020)
Article
Chemistry, Physical
Sangeetha Dharmalingam, Omkumar Meenakshisundaram, Vaidhegi Kugarajah
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2020)
Article
Materials Science, Multidisciplinary
Dinesh Kumar Ravikumar, Sandeep Ragavan, Sangeetha Dharmalingam
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2020)
Article
Environmental Sciences
Felix Swamidoss Victor, Vaidhegi Kugarajah, Mohan Bangaru, Shivendu Ranjan, Sangeetha Dharmalingam
Summary: The study successfully developed a nanocomposite filter media by blending PVDF with TNT through electrospinning, which demonstrated a high bacterial filtration efficiency. Through analysis and evaluation of the nanocomposite filter media, it was found to have great potential for application in clean air management.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Engineering, Biomedical
Rajalakshmi Ekambaram, Moogambigai Sugumar, Elamathi Swaminathan, Arul Princy Micheal Raj, Sangeetha Dharmalingam
Summary: The study introduces a novel electrospun polymeric nanofibrous scaffold enriched with pharmaceutical bioactive materials extracted from Morinda citrifolia for efficient skin wound healing therapy. The scaffold demonstrated excellent keratinocyte proliferation and adhesion in in vitro analysis and exhibited antibacterial efficacy. Chemical analysis revealed that the pharmaceutical components in Morinda citrifolia played an active role in promoting healing.
BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Physical
Vaidhegi Kugarajah, Moogambigai Sugumar, Elamathi Swaminathan, Nagaraj Balasubramani, Sangeetha Dharmalingam
Summary: By incorporating sulphonated zinc oxide nanorods into a sulphonated polymer, the membrane exhibits improved water uptake and ion transfer capacity, making it suitable for microbial fuel cells.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Engineering, Biomedical
Rajalakshmi Ekambaram, Vikas Paraman, Lokeshwar Raja, Manoj Kumar Suresh, Sangeetha Dharmalingam
Summary: This study focused on a novel approach for periodontal regeneration, utilizing zirconia nanoparticles loaded with curcumin incorporated into polymer nanofibrous scaffolds. The materials demonstrated good cyto-compatibility and antibacterial properties, showing potential for effective periodontal regeneration applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Vaidhegi Kugarajah, John Solomon, Kavinila Rajendran, Sangeetha Dharmalingam
Summary: This research explores the use of biocathodes with eggshell as a low-cost and efficient alternative to platinum-based catalysts in microbial fuel cells, resulting in improved electricity generation and nitrate removal. Microbial consortia analysis revealed the presence of denitrifying bacteria such as Pseudomonas, Azoarcus, Thauera, and Wolinella, contributing to better performance and indicating potential for scaling up MFCs.
PROCESS BIOCHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Rajalakshmi Ekambaram, Moogambigai Sugumar, Swetha Karuppasamy, Prabalaya Prasad, Sangeetha Dharmalingam
Summary: This study focuses on the design and development of wheatgrass-enriched nano-fibrous scaffolds for wound healing. The bio-active ingredients in wheatgrass extract showed high potential in binding to the wound healing enzyme COX-2. The synthesized nanofibrous bio-material demonstrated active properties in promoting skin wound healing.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Polymer Science
Sangeetha Dharmalingam, Omkumar Meenakshisundaram, Felix Swamidoss Victor
Summary: This study investigates the effect of amine-functionalization of luffa fibers on the drilling characteristics of luffa/epoxy composites. The results show that the amine-functionalized composites exhibit better machinability and reduced delamination, attributed to the improved interfacial bonding and compatibility between the fiber and the polymer matrix.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rajalakshmi Ekambaram, Saisupriyalakshmi Saravanan, Sangeetha Dharmalingam
Summary: Electro-spinnable polymeric materials combined with sulphonated poly ether ether ketone and resveratrol have been demonstrated to be an effective 2D nanomaterial for skin wound healing. The fabricated nanocomposites exhibited enhanced skin cell proliferation and adhesion, as well as a uniform nano-sized distribution. The controlled release of resveratrol showed good biocompatibility and the potential to treat wounds with bacterial infections.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2022)
Article
Polymer Science
Saranya Rathinavel, Moogambigai Sugumar, Elamathi Swaminathan, Sudharshan Kubendren, Kalaimagal Samvasivan, Dharmalingam Sangeetha
Summary: Researchers synthesized nanofibrous scaffolds of polycaprolactone (PCL) incorporated with the extract of P. amboinicus for wound healing application. The fabricated nanofiber showed a well-structured, hydrophilic and antibacterial property, making it suitable for promoting wound healing.
JOURNAL OF POLYMER RESEARCH
(2023)
Article
Chemistry, Applied
Rajalakshmi Ekambaram, Saisupriyalakshmi Saravanan, Nishiya Selvam, Sangeetha Dharmalingam
Summary: This study reported the fabrication of novel nanofiber materials using green synthesis for combating skin cancer cells, with good antibacterial and antioxidant properties demonstrated through comprehensive characterizations. The nano-composite fibrous scaffold showed promise as an effective transdermal patch for melanoma applications.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS
(2021)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
