Article
Engineering, Electrical & Electronic
Sudip Kuila, Surajit Bagchi
Summary: In this work, an inexpensive, rapid, and reproducible Nitrate sensing system was developed and characterized to monitor and diagnose Asthmatic conditions using exhaled breath condensate (EBC) as a biosample. The system showed a fast response and high agreement with standard nitrate tests.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Pedro Conceicao, Joana F. B. Barata, Miguel A. Hernandez-Rodriguez, Paula S. S. Lacerda, Maria G. P. M. S. Neves, Lus D. Carlos, Tito Trindade
Summary: This work presents an example of luminescent ratiometric thermal sensor using 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin (TPFPP) and colloidal ZnS/AOT quantum dots (QDs). The nanoassemblies prepared based on the inner filter effect showed good temperature reversibility and a maximum relative thermal sensitivity of 0.95%°C-1 at 50°C.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Engineering, Electrical & Electronic
Qingrong Ma, Buayishamu Kutilike, Nuerguli Kari, Shawket Abliz, Abliz Yimit
Summary: Hybrid TCPP-g-C3N4 composites were facilely synthesized through grinding and ethanol dispersion, and their aggregation behaviors in different pH conditions were studied. It was found that the composite under basic conditions showed fine response to SO2 and H2S, with the gas-sensitive mechanism being protonation and deprotonation process according to UV-vis spectroscopy.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2021)
Review
Biochemistry & Molecular Biology
Diana Mathew, Subramaniam Sujatha
Summary: The advancement of porphyrins as artificial nucleases has shown potential therapeutic applications. Through chemical modifications of the porphyrin macrocycle, improvements have been made to enhance spectroscopic properties and adapt them as artificial receptors for molecule recognition. Research in the past two decades has focused on porphyrin-DNA interactions, evolving from simple to more complex entities. Specific emphasis has been placed on the effects of porphyrins on DNA cleavage potency.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Engineering, Electrical & Electronic
Min Shao, Haonan Sun, Rong Zhang, Lipin Li, Yinggang Liu, Xueguang Qiao
Summary: An in-fiber humidity sensor based on black phosphorus (BP)-polyvinyl alcohol (PVA) was proposed and experimentally demonstrated. The maximum sensitivity of the sensor was found to be 0.6106 nm/%RH in the humidity range of 40-50%RH. The combination of BP and PVA not only improved the humidity sensitivity of the sensor but also enhanced the stability of BP in air. The sensor showed low instability, a measurement error brought by temperature, and a fast response time suitable for human breathing measurement.
OPTICAL FIBER TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Rasha M. Kamel, Ahmed Shahat, Aly H. Atta, Mohamed M. A. Farag-Allah
Summary: The study created an optical, chemical sensor using mesoporous silica surface for colorimetric recognition of Cu(II) and Pd(II) ions with high sensitivity. The sensor was characterized and modeled for adsorption efficiency, showing effective detection and extraction of target ions from E-wastes.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Analytical
Noel Nesakumar, Soorya Srinivasan, Subbiah Alwarappan
Summary: This article provides a detailed review on the synthesis methods of graphene quantum dots (GQDs) and their applications in biosensing, including fluorescence, photoluminescence, chemiluminescence, electrochemiluminescence, fluorescence resonance energy transfer, and electrochemical techniques. The review sheds light on critical issues and widens the potential applications of GQDs for improved analytical response in future biosensor designs.
Review
Chemistry, Analytical
Peuli Nath, Kazi Ridita Mahtaba, Aniruddha Ray
Summary: Fluorescence-based detection techniques are widely used in biomedical and environmental research for their high sensitivity, selectivity, and short response time. However, the bulky and expensive readout devices and the need for supervision limit their accessibility in resource-limited settings. To overcome these challenges, efforts have been made to integrate fluorescence-based assays into miniature platforms and couple them with portable readout devices like smartphones and wearable sensors, enabling point-of-care detection of bio-chemical analytes. This review highlights some recently developed portable fluorescence-based assays by discussing the design of fluorescent sensor molecules, their sensing strategy, and the fabrication of point-of-care devices.
Article
Chemistry, Analytical
Jialiang Chen, Yuanzhang Zhao, Ying Wan, Longyi Zhu, Bin Li, Jiangnan Wu, Lisen Li, Yaqi Huang, Yuansheng Li, Xuwei Long, Shengyuan Deng
Summary: This study demonstrates the great potential of the electrochemiluminescence (ECL) technique in probing microscopic biointerfacial events and establishes its effectiveness in profiling ion-channel activities through modeling an artificial lipoid-supported porin ensemble. The researchers explore the basic ECL properties, brightness response, membrane-binding strengths, and anionic transmembrane kinetics, and identify a new ECL symporter. The findings provide insights for the evaluation of life-mimicking membrane permeation and broaden the potential applications of ECL in measuring diverse surface-confined transient scenarios.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Somasundaram Chandra Kishore, Kanagesan Samikannu, Raji Atchudan, Suguna Perumal, Thomas Nesakumar Jebakumar Immanuel Edison, Muthulakshmi Alagan, Ashok K. Sundramoorthy, Yong Rok Lee
Summary: This study provides an overview of the latest wireless and smartphone-supported chemical sensors. The market opportunities for these sensor systems include environmental monitoring, healthcare and medicine, food quality, sport, and fitness. The study suggests that advancements in technology will lead to smaller, lighter, cost-effective, versatile, and durable devices. Wireless and smartphone-supported chemical sensors are expected to play a significant role in the sensor Internet of Things.
Article
Chemistry, Analytical
Vedran Budinski, Denis Donlagic
Summary: This paper introduces a miniature all-silica flow-injection sensor with optical fiber-coupled microcell for spectral absorption measurements and microfluidic reagent injection system, allowing for colorimetric chemical sensing in compact spaces and at very low flow rates.
Article
Chemistry, Analytical
Meiting Hou, Liangfei Fan, Xia Fan, Xin Liang, Weihua Zhang, Yubin Ding
Summary: A ratiometric sensor array Py-PP was constructed to discriminate GAGs, showing excellent discrimination ability towards Hep, HA, Chs, and DS. The sensor array was effective in both PBS and 5% serum media, and could detect trace GAG contaminants in Hep with 100% accuracy. The Py-PP sensor array proved to be a powerful tool for accurate discrimination of GAGs.
ANALYTICA CHIMICA ACTA
(2021)
Article
Engineering, Chemical
Suherman Suherman, Muh Supwatul Hakim, Agus Kuncaka
Summary: A new optical chemical sensor was developed using the Sol-Gel method for determination of Ni2+ ions in aqueous solutions. The sensor showed optimal response towards Ni2+ ions at pH 8.5 with a contact time of 10 minutes. The calibration curve had a linear concentration range of 1-5 mg L-1, with a detection limit of 0.111 mg L-1.
Article
Energy & Fuels
Diego Valencia
Summary: This study used quantum chemical calculations to investigate V-or Ni-containing petroporphyrins, focusing on their electronic structure and chemical bonding characteristics. The addition of alkyl substituents and metal centers was found to affect the chemical bonds and aromaticity in the rings. In-depth studies were conducted on the N-M chemical bonds, revealing higher covalency in the N-Ni bonds. The Laplacian Bond Orders explained the resistance of these compounds in crude oils.
Article
Chemistry, Analytical
Dongmin Jia, Qingwen Pan, Ruiyue Hu, Weihua Zhang, Yubin Ding
Summary: Boronate affinity-based indicator displacement assay is a promising approach to develop high performance saccharide sensors, but improving the sensitivity in aqueous solutions has been difficult due to the hydrophilic and hydromimetic nature of saccharides. Inspired by the natural photosynthesis system, an enhanced FRET complex named 4Esculetin-BAAP was designed with high energy donor to acceptor ratio to improve light harvesting efficiency. The sensor array 4EBSA was constructed using complex 4Esculetin-BAAP and showed accurate and sensitive recognition of monosaccharides in both PBS and serum samples. It was also capable of distinguishing glucose and its phosphorylated product in mixed form in serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)