Article
Optics
Tonglei Cheng, Xiaoyu Chen, Xin Yan, Xuenan Zhang, Fang Wang, Takenobu Suzuki, Yasutake Ohishi
Summary: A nonlinear temperature sensor based on dispersive wave (DW) and soliton in a silica microstructured optical fiber was proposed. By detecting the central wavelength shift of DW and soliton, the sensor showed high sensitivity to temperature changes. Experiments and theory demonstrated that both DW and soliton can be used effectively for high sensitivity temperature sensing applications.
Article
Polymer Science
Federica Bertela, Chiara Battocchio, Giovanna Iucci, Simona Ceschin, Dario Di Lernia, Flaminia Mariani, Andrea Di Giulio, Maurizio Muzzi, Iole Venditti
Summary: Ecosystems worldwide are being impacted by microplastic particles, which are widely present in water, sediments, and aquatic organisms. However, these particles are rarely used in laboratory studies due to their limited availability and high cost, especially for tracing purposes. In this study, a new, easy, and cost-effective method for preparing fluorescent microplastic particles is proposed. The particles, made of P(S-co-MMA) polymer with a diameter of 0.7-9 microns, are fluorescently labeled with either rhodamine B isothiocyanate (RITC) or fluorescein isothiocyanate (FITC). The loading of the dyes is optimized, and the particles are characterized using various techniques. Preliminary tests on aquatic organisms demonstrate the potential use of these fluorescent microplastic particles in bioimaging studies.
Article
Agriculture, Multidisciplinary
Jin Wang, Xing Shen, Peng Zhong, Zhaodong Li, Qiushi Tang, Xinan Huang, Anatoly V. Zherdev, Boris B. Dzantiev, Sergei A. Eremin, Zhili Xiao, Hongtao Lei, Xiangmei Li
Summary: A heterologous immunoassay strategy was designed to enhance the sensitivity for the detection of banned dye RB in fraudulent food in this study. The proposed immunoassay can be used for the surveillance screening of RB in a range of seasoning foods, indicating the heterologous strategy is an effective approach to enhance sensitivity in an immunoassay.
CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE
(2021)
Article
Chemistry, Analytical
Laura D. Casto-Boggess, Matin Golozar, Anna L. Butterworth, Richard A. Mathies
Summary: Fluorescence labeling and detection platforms are powerful tools for high-sensitivity bioanalysis, especially when targeting trace levels of analytes. This study optimized the labeling and detection of Pacific Blue-tagged amino acids, achieving 100 pM sensitivities and high-efficiency separations. The research developed a quantitative optimization model that can be applied to various reactive probes and targets, making it particularly useful for analyzing trace amine and amino acid biosignatures in extraterrestrial samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Ilaria Fratoddi, Chiara Battocchio, Giovanna Iucci, Daniele Catone, Antonella Cartoni, Alessandra Paladini, Patrick O'Keeffe, Silvia Nappini, Sara Cerra, Iole Venditti
Summary: This paper presents the synthesis of silver nanoparticles (AgNPs) functionalized with fluorescent molecules, specifically xanthene-based dyes, and evaluates their chemical structure and optical properties. Characterization of AgNPs-RITC and AgNPs-FITC was conducted using UV-Vis spectroscopy, dynamic light scattering (DLS), and synchrotron radiation X-ray photoelectron spectroscopy (SR-XPS). The study demonstrated the potential of these AgNPs in biosensing and imaging applications by combining plasmonics and fluorescence.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Physical
Subhabrata Mabhai, Malay Dolai, Surya Kanta Dey, Anamika Dhara, Sujata Maiti Choudhury, Bhriguram Das, Satyajit Dey, Atanu Jana, Deb Ranjan Banerjee
Summary: The study successfully synthesized a new luminescent sensor that can detect three metal ions with high sensitivity and selectivity. The different effects of different metal ions allowed for efficient recognition and detection of Al3+, Cr3+, and Cu2+.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Chemistry, Applied
Lei Jiang, Lin Yuan, Yingying Xiang, Fei Song, Wenjun Jiang, Xiuling Ji, Yujiao Tu
Summary: Researchers developed yellow fluorescent carbon dots for the quick detection of As3+ in the environment. They obtained good detection ranges of 0-5 μg/L and 0-50 μg/L using fluorescence and UV absorbance methods, respectively. The fluorescence quenching process of As3+ towards the carbon dots was verified.
Article
Agronomy
Wantong Jia, Huilin Yu, Jinyu Fan, Jiyue Zhang, Hongyu Pan, Xianghui Zhang
Summary: Our study investigated the role of histidine kinases in Cochliobolus heterostrophus. Deletion of the HK coding gene ChNIK1 increased the sensitivity of the fungus to A-ITC. Other HK genes did not affect A-ITC sensitivity, but were essential for conidiation and response to other stress factors.
PEST MANAGEMENT SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Zhibin Yu, Chang Li, Zhengwei Chen, Yunfei Li, Xing Han
Summary: This study established a thermo-mechanical coupling model for laser quenching of ASTM 1045 material and obtained the transient law of temperature and microstructural transformation during quenching through numerical simulation. The model was validated through experiments and process parameters of laser quenching were sampled and analyzed using the Monte-Carlo method.
METALS AND MATERIALS INTERNATIONAL
(2021)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Article
Chemistry, Analytical
Jianli Zhang, Alexander D. Wiener, Raymond E. Meyer, Cheuk W. Kan, David M. Rissin, Bharathi Kolluru, Christopher George, Carmen I. Tobos, Dandan Shan, David C. Duffy
Summary: This study presents methods to improve the quantification of digital bead assays (DBA), such as digital enzyme-linked immunosorbent assay (ELISA), which are widely used for highly sensitive protein measurement in clinical research and diagnostics. By changing the calculation method for the average number of enzymes per bead (AEB) and improving the determination of average product fluorescence intensity, the accuracy and robustness of DBA can be significantly improved.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
M. Tutov, A. A. Sergeev, N. Shamich, A. K. Chepak, A. Yu Mironenko
Summary: In this study, a series of branched organosilicon compounds with varying numbers of rhodamine 6G groups were synthesized using the click conjugation strategy. Physical and photophysical methods were used to characterize the compounds and it was found that the absorption cross section of conjugated chromophores is inversely related to their local concentration, while fluorescence intensity is dependent on dendrimer concentration. The fluorescence quenching mechanisms were hypothesized to be PET and PDT based on experimental data, theoretical calculations, and literature review.
Article
Chemistry, Multidisciplinary
Shiqi Hu, Haiping Jiang, Jianqiang Zhu, Jinqiang Wang, Shunhao Wang, Jianbin Tang, Zhuxian Zhou, Sijin Liu, Youqing Shen
Summary: Research shows that rhodamine B isothiocyanate derivatives (RBITCs) exhibit unique tumor-specific fluorescence, which can be utilized for cancer imaging and early diagnosis.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Chemistry, Analytical
Minglu Zhang, Shuo Wang, Yu Fu, Meng Meng, Hongzhen Jin, Wei Zhao
Summary: Biothiols, particularly cysteine (Cys), play crucial roles in human pathophysiology and have significant potential as clinical biomarkers for various diseases. In this study, a near-infrared (NIR) fluorescence probe named CyOH-NCS was developed to specifically detect Cys in physiological conditions and living systems. The probe showed excellent performance in visualizing Cys in living cells, zebrafish, and mice. Additionally, the probe exhibited responsive hydrogen sulfide (H2S) release, suggesting its potential dual application in pathophysiological studies.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Natpapas Wiriyachaiporn, Siriwan Sirikaew, Nawakarn Chitchai, Pareena Janchompoo, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Ekawat Pasomsub, Deanpen Japrung
Summary: The visual colorimetric rapid screening system, based on a lateral flow device, demonstrated good specificity to influenza A and B nucleoproteins without cross reactivity to other closely related respiratory viruses. It showed high sensitivity, detecting as low as 0.04 and 1 ng of influenza A and B protein content per test, respectively, within 10 minutes. Comparing to commercial tests, the system exhibited a four-to-eight-fold higher sensitivity and correlated well with standard molecular approaches in pre-clinical evaluation.
Article
Chemistry, Organic
Smita Bait, Suvidha Shinde, Ravindra Adivarekar, Nagaiyan Sekar
Summary: In this study, fluorescent acid azo dyes with excited state intramolecular proton transfer (ESIPT) core, based on benzothiazole and benzimidazole, were synthesized and characterized. The spectral characteristics of these dyes in different solvents showed distinct Stokes shifts. The dyed wool and silk fabrics exhibited high exhaustion percentages and demonstrated antibacterial and UV protective properties.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Virology
Drishya Prakashan, Narlawar S. Shrikrishna, Manisha Byakodi, K. Nagamani, Sonu Gandhi
Summary: The COVID-19 pandemic has highlighted the need for a rapid diagnostic device. Lateral flow immunoassays (LFIA) have the advantage of providing quick results, being easy to handle, and cost-effective. This study developed an LFIA using antibody-labeled gold nanoparticles for the detection of the Receptor-Binding Domain (RBD) of SARS-CoV-2. The optimized LFIA strips showed a limit of detection of 1ng/ml and high sensitivity and specificity when compared to the gold standard. The developed LFIA can be used as a portable and cost-effective diagnostic device for rapid detection of SARS-CoV-2.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Review
Chemistry, Multidisciplinary
Zeba Khan, Nagaiyan Sekar
Summary: Xanthene dyes have remarkable photophysical properties and photostability, making them promising candidates for imaging/sensing/tracking/labeling probes. However, their emission wavelength ≤ 600 nm and small Stokes shift restrict their use in biological applications. This review provides a comprehensive list of deep red to NIR xanthene-hemicyanine and xanthene-coumarin hybrids, along with synthetic strategies and discussions on the effects of substituents, pi-conjugation, and ring structure on their photophysical properties. Applications of these hybrids based on fluorophore-linker strategy and spirocyclization are also discussed. This review emphasizes the structure-spectroscopic relationships, which will aid in the design of new deep red to NIR xanthene analogs.
Article
Environmental Sciences
Maitri Shah, Pratik Kolhe, Sonu Gandhi
Summary: In this study, a sensitive detection method against the toxic pesticide endosulfan was proposed using multiwalled carbon nanotubes (MWCNT). The detection limit for endosulfan was found to be 0.184 ppt in standard buffer. The fabricated immunosensor showed good cross reactivity with other pesticides and can be used for successful detection of endosulfan in the agricultural sector.
Article
Biophysics
Subhasis Mahari, Drishya Prakashan, Sonu Gandhi
Summary: This study developed an immunochromatographic (ICG) strip for the detection of Salmonella using in-house generated antibodies conjugated with gold nanoparticles. The strip was integrated with a colorimetric method and the ColorGrab application on a smartphone. The developed diagnostic platform showed the ability to detect Salmonella in a linear range of 107-100 CFU/mL, and the results were further confirmed by the smartphone-based ColorGrab application. The ICG strips were validated with spiked fecal, meat, and milk samples, providing results in 10 minutes and remaining stable for 28 days at 4°C and 37°C. Therefore, the in-house fabricated ICG strip can be utilized as a portable and cost-effective diagnostic device for rapid detection of Salmonella strains in food samples.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Materials Science, Textiles
Praful. S. S. Patil, Puja. O. O. Gupta, Gauri. S. S. Ingole, Nagaiyan Sekar
Summary: Anthrone- and aniline-based azo dyes were synthesized, characterized, and applied to various fabrics. The dyed fabrics showed different fastness properties, with polyester and nylon performing better than wool and acrylic. The dyes also exhibited strong ultraviolet protection activity and antibacterial properties. In addition, the chemical reactivity descriptors were calculated using density functional theory.
FIBERS AND POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Supriya H. Ramugade, Sekar Nagaiyan
Summary: Disperse Red 177(9a), Disperse Red 343(9b), Disperse Blue 165(9c), Disperse Blue 165.1(9d), Disperse Blue 366 (9e), and Disperse Blue 148(9f) were studied in a solvent. The use of 9 (a-f) azo disperse dyes on polyester fabric, along with traditional and silicone nanomicelle techniques, resulted in equal washing, light, and rubbing fastness. The reduction in particle size of azo dyes through nanoemulsions allowed for direct transportation into the fiber core, eliminating the need for auxiliary dyes.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
(2023)
Article
Biotechnology & Applied Microbiology
Akanksha Roberts, Himani Dhanze, G. Taru Sharma, Sonu Gandhi
Summary: A rapid immunosensor for the detection of Japanese encephalitis virus (JEV) has been developed using a smartphone-based portable device. The immunosensor showed high sensitivity and specificity, and demonstrated good accuracy and sensitivity in clinical testing. This technique has the potential to be developed into a one-step rapid diagnostic tool for JEV, especially in rural areas.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Article
Environmental Sciences
Narlawar Sagar Shrikrishna, Ajeet Kaushik, Sonu Gandhi
Summary: This study investigates the use of silica alcogel as an immobilization matrix for the development of a nano-enabled chromagrid-lightbox sensing system. The system is capable of detecting monocrotophos pesticide in environmental and food samples using a smartphone. The developed system is eco-friendly and can be manufactured using recyclable waste plastic.
Review
Chemistry, Applied
Vandana Kumari Shukla, Goutam Chakraborty, Alok K. Ray, Sekar Nagaiyan
Summary: BODIPY dyes have excellent features but their application is limited due to narrow absorption and emission range. Recent developments in introducing fused BODIPYs and aza-BODIPYs have shown promise in red shifting the photophysical properties. This review summarizes their properties, synthesis, and applications in biomedical and optoelectronic fields.
Article
Chemistry, Multidisciplinary
Harshada More, Vandana Kumari Shukla, Praful Patil, Nagaiyan Sekar
Summary: This study investigates the growth inhibitory potential of fifteen coumarin molecules with substitutions at positions C-3 and C-6 using DFT and TD-DFT. The experimentally determined toxicity values are correlated to the calculated molecular descriptors, revealing direct or inverse trends.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
(2023)
Article
Green & Sustainable Science & Technology
Raghuraj Singh Chouhan, Sonu Gandhi, Suresh K. Verma, Ivan Jerman, Syed Baker, Marko Strok
Summary: The demand for alternative energy sources from non-recyclable waste materials is a hot topic in future industries. Microbial Fuel Cells (MFC) represent a new energy source with unique qualities, harnessing energy from waste materials, providing localized power solutions, and promoting efficient power conversion. Improving MFC performance through research on anode materials, such as carbon nanotubes, graphene, graphitic carbon nitride, MXene, and their nanocomposites, is an important focus. This review provides a comprehensive summary of recent developments, mechanism and operational principles, applications, challenges and future perspectives related to MFC anode materials.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2023)
Article
Chemistry, Physical
Suryapratap J. Sharma, Nagaiyan Sekar
Summary: In this study, three quinoid zwitterionic dye sensitizers were investigated for their applications in dye-sensitized solar cells and nonlinear optical properties. The computational results showed that one of the dyes (ZIDM) exhibited better charge transfer and higher light harvesting efficiency compared to the others. It was also found that the dyes could easily bind with the TiO2 cluster through a monodentate binding mode. Moreover, ZIDM demonstrated higher nonlinear optical properties than the other dyes.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Physical
Suryapratap J. Sharma, Keval K. Sonigara, Hiren K. Machhi, Saurabh S. Soni, Nagaiyan Sekar
Summary: Dye-sensitizers designed from coumarin backbone have versatile performance in dye-sensitized solar cells (DSSC). In this study, different coumarin-based sensitizers were designed and computational calculations were performed to predict their light harvesting capability and non-linear optical properties. The reaction between the sensitizers and TiO2 revealed different binding modes for different anchoring groups. Sensitizers with 2-cyanoacrylic acid anchors showed a more planar geometry and higher power conversion efficiency in the DSSC device.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Environmental Sciences
Maitri Shah, Pratik Kolhe, Sonu Gandhi
Summary: In this study, a novel nanohybrid was synthesized for the sensitive detection of endosulfan, and was used to fabricate an electrochemical electrode. The nanohybrid exhibited excellent optoelectrical potential and chemical characteristics, showing promising applications.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
