Article
Chemistry, Analytical
Aitor Sorribes-Soriano, Francesc Albert Esteve-Turrillas, Sergio Armenta, Jose Manuel Herrero-Martinez
Summary: In this study, a molecularly imprinted polymer (MIP)-coated stir bar for recognizing diazepam was prepared. The MIP was synthesized using methacrylic acid as a functional monomer, diazepam as a template, ethylene glycol dimethacrylate as a crosslinker, and azobisisobutyronitrile as an initiator. The resulting polymer-modified stir bar was characterized and used in a stir-bar-sorptive-extraction (SBSE) method in combination with ion mobility spectrometry (IMS) or ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS/MS). The MIP-SBSE coupled with UHPLC-MS/MS showed satisfactory results in quantifying traces of diazepam in water samples, while the MIP-SBSE using IMS exhibited high sensitivity for rapid screening of the compound in different matrices.
MICROCHEMICAL JOURNAL
(2023)
Article
Environmental Sciences
Jing Wang, Zhehao Wang, Zhonglin Chen, Pengwei Yan, Jimin Shen, Jing Kang
Summary: This paper proposes a new method for preparing a molecularly imprinted polymer (MIPs)-coated magnetic stir bar for bisphenol A (BPA). The MIPs coating exhibited better adsorption capacity and selectivity for BPA compared to the non-imprinted coating. The method is simple, convenient, selective, and sensitive, making it suitable for the analysis and detection of trace amounts of BPA in complex samples.
Article
Chemistry, Multidisciplinary
Yahan Cui, Liyan Jiang, Huiyu Li, Di Meng, Yanhua Chen, Lan Ding, Yang Xu
Summary: The study developed a new method for determining sulfa antibiotics in feeds by molecularly imprinted electrospun nanofibre membrane (MIM) assisted stir bar sorptive extraction, achieving selective enrichment of SAs.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Review
Polymer Science
Abderrahman Lamaoui, Abdellatif Ait Lahcen, Aziz Amine
Summary: This review explores the potential of molecularly imprinted polydopamine (MIPda) in cutting-edge sensing applications, including its preparation, sensing applications, and synthesis methods. It also discusses the challenges and prospects for future developments in this research field.
Review
Biochemical Research Methods
Man He, Yuxin Wang, Qiulin Zhang, Lijuan Zang, Beibei Chen, Bin Hu
Summary: This review summarizes the recent progress of stir bar sorptive extraction (SBSE) in the past six years, focusing on the preparation methods and new materials for coated stir bars. The discussion also includes the development and prospects of SBSE as an efficient sample pretreatment technique in real sample analysis.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Review
Chemistry, Analytical
Sayyed Hossein Hashemi, Massoud Kaykhaii
Summary: This article reviews the various applications, advantages and disadvantages of nano-coatings as media for micmextraction by stir bar, analyzing the critical evaluation of currently available methods. It is shown that using nano-coatings as coatings can improve the efficiency of stir bar sorption extraction.
Article
Chemistry, Analytical
Dinh-Hai-Ngan Nguyen, Quang-Hai Le, Tuan-Linh Nguyen, Van-Tuan Dinh, Hoai-Nam Nguyen, Hong -Nam Pham, Tien-Anh Nguyen, Luong-Lam Nguyen, Thi-Mai-Thanh Dinh, Van-Quynh Nguyen
Summary: This work presents the development and application of micropatterned molecular imprinting in a conductive polymer film for the detection of diclofenac molecules. The technique involves combining nanosphere lithography and electrochemical polymerization to generate a nanos-tructured polymer on a glassy carbon electrode. The resulting molecularly imprinted polymer electrode shows good recognition properties for diclofenac molecules in phosphate-buffered saline solution, with increased sensitivity and a lower limit of detection compared to a non-molecular imprinted polymer electrode.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Somchai Boonpangrak
Summary: Molecularly imprinted polymers (MIPs) are highly specific materials for the detection of molecules of interest in analytical chemistry. MIPs possess chemical and physical resistance, inexpensive synthesis, and ease of preparation, making them suitable for various applications. Lipid-soluble vitamin-imprinted polymers have significant applications in vitamin detection.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Elif Esen, Bilgen Osman, M. Nalan Demir
Summary: MLT-imprinted microbeads were prepared for SPE of MLT from edible plants. The MIP showed high adsorption capacity and selectivity for MLT, leading to efficient extraction from various plant samples for HPLC analysis. The SPE method using MLT-PEMATrp microbeads was highly effective and had a low LOD.
MICROCHEMICAL JOURNAL
(2021)
Review
Polymer Science
Erinn K. Reville, Elizabeth H. Sylvester, Sarah J. Benware, Shreeya S. Negi, Erik B. Berda
Summary: Molecularly imprinted polymers (MIPs) combine the complexity of receptor proteins with the tunability of synthetic research, and have potential in the recognition of target molecules. The aim of MIP research is to achieve similar recognition accuracy as receptor proteins while tailoring functional properties for advanced applications.
Article
Chemistry, Applied
Christine Unger, Peter A. Lieberzeit
Summary: Molecularly imprinted polymers show potential in replacing biological recognition species, such as antibodies, in sensing applications. However, challenges remain in generating surface imprints, increasing binding capacity, and selectivity.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Review
Polymer Science
Ike Susanti, Mutakin Mutakin, Aliya N. Hasanah
Summary: Molecularly imprinted mesoporous silica (MIP-MS) enhances the analytical performance of solid-phase extraction sample preparation, influenced by various materials and conditions including template molecular concentration, chemical ratio, type and concentration of functional monomer. Factors affecting the analytical performance in adsorption-desorption study include pH, mass sorbent, eluting solvent, and washing solvent.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Article
Chemistry, Analytical
P. Garcia-Atienza, F. A. Esteve-Turrillas, S. Armenta, J. M. Herrero-Martinez
Summary: Drug abuse can be easily identified through oral fluid analysis. A selective and sensitive methodology using a molecularly imprinted polymer (MIP) as a solid phase extraction sorbent, followed by ion mobility spectrometry, has been proposed for the fast identification of drug abuse in oral samples.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Analytical
Thomas Bouvarel, Nathalie Delaunay, Valerie Pichon
Summary: This review discusses the latest developments in miniaturization of molecularly imprinted polymers to meet the societal demand for reliable, fast, affordable, and solvent/sample saving analyses. Different polymerization routes for producing miniaturized molecularly imprinted polymers in capillaries or chip channels are investigated, along with their potential applications in various separation techniques.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Lan Luo, Chengkai Lv, Yukun Xing, Fen Ma, Jie Kong, Fangfang Chen
Summary: This study developed porous designed molecularly imprinted polymers (PMIPs) based on cleavage hyperbranched polymers for thiamine hydrochloride controlled release. The PMIPs showed higher drug loading and longer release time compared to the porous non-imprinted polymers (PNIPs), providing a path for fabricating improved imprinted materials with higher adsorption capacity and faster recognition kinetics.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)