Article
Biochemistry & Molecular Biology
Curtis A. Gibbs, David S. Weber, Jeffrey J. Warren
Summary: Short-range non-covalent interactions between amino acid residues play a crucial role in determining protein structures and functions. The interactions between the thioether of methionine and the aromatic rings of tyrosine, tryptophan, and/or phenylalanine are highly favorable. A new bioinformatics survey of protein structures reveals the presence of clusters formed by the localization of these aromatic residues around the methionine thioether. These clusters, known as 3-bridge clusters, show a network of interactions involving the methionine sulfur, methylene, methyl groups, and nearby aromatic residues. The findings suggest potential functional roles of 3-bridge clusters in proteins.
Article
Chemistry, Applied
Emma Alexander, Jose Chavez, Luca Ceresa, Michael Seung, Danh Pham, Zygmunt Gryczynski, Ignacy Gryczynski
Summary: We observe efficient room temperature phosphorescence from coumarin 106 embedded in a poly (vinyl alcohol) film. This phosphorescence occurs at 465 nm, which is outside the absorption band, when directly excited to the triplet state. The phosphorescence properties, such as spectra, lifetimes, and temperature dependence, are similar for UV and blue excitations but the emission anisotropy differs significantly.
Article
Chemistry, Multidisciplinary
Chuangxu Cai, Feifei Wang, Xiuyun Xiao, Wangjian Sheng, Shu Liu, Jun Chen, Jie Zheng, Ran Xie, Zengbing Bai, Huan Wang
Summary: This study presents a method for the modification and macrocyclization of thiazole-containing peptides through palladium-catalyzed δ-C(sp(2))-H olefination. The thiazole and neighboring amide bonds act as directing groups, enabling site-specific olefination of phenylalanine, tryptophan, and tyrosine residues. This chemistry has a broad substrate scope and provides easy access to peptide-peptide conjugates and peptide macrocycles.
CHEMICAL COMMUNICATIONS
(2022)
Article
Biophysics
Jelena D. Pajovic, Radovan J. Dojcilovic, Slavka Kascakova, Matthieu Refregiers, Dusan K. Bozanic, Vladimir Djokovic
Summary: Functionalized gold nanoparticles using amino acid tryptophan and vitamin riboflavin showed enhanced resonance energy transfer (RET) efficiency, leading to a different photobleaching dynamics compared to molecules in solution. This effect was utilized for detection of the nanoparticles within autofluorescent biological material.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Multidisciplinary Sciences
Shaymus Contorno, Richard E. Darienzo, Rina Tannenbaum
Summary: The study focused on utilizing Raman spectroscopy to analyze aromatic amino acids as a potential biomarker for breast cancer detection. Results showed that cancerous breast tissues and cells exhibit significant overexpression of aromatic amino acids, suggesting the possibility of using these Raman bands as a diagnostic tool for breast cancer.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Alexander Mordhorst, Priyavathi Dhandapani, Susann Matthes, Valentina Mosienko, Michael Rothe, Mihail Todiras, Julie Self, Wolf-Hagen Schunck, Anja Schutz, Michael Bader, Natalia Alenina
Summary: Serotonin synthesis involves the hydroxylation of tryptophan, with most vertebrates having two known enzymes for this step. However, even in animals lacking these two enzymes, there is still some serotonin production, suggesting the presence of a third enzyme. The study found evidence that phenylalanine hydroxylase (PAH) may act as a third tryptophan hydroxylase in mammals, contributing to serotonin levels in the blood and potentially serving as a local source of serotonin in organs where other TPHs are not expressed.
Review
Biochemistry & Molecular Biology
Ancuta Dinu, Constantin Apetrei
Summary: In recent years, the development of sensors and biosensors has become a hot topic in interdisciplinary research, attracting researchers from various fields. This paper synthesizes the most relevant studies on the construction and functioning of versatile devices, as well as electrochemical sensors and biosensors. It focuses on the role and importance of the amino acids phenylalanine, tyrosine, and tryptophan in the central nervous system, and the application of conductor polymers and molecularly imprinted polymers in achieving electrochemical sensors and biosensors. The paper also analyzes the performance of sensors and biosensors developed so far for amino acid detection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
M. S. S. Vinod Mouli, Harsha Gopal Agrawal, Mohit Kumar, Ashutosh Kumar Mishra
Summary: The luminescence and self-assembly behavior of two aromatic dipeptides with structural variation were investigated in this study. The results indicate the significant influence of structural variation on the functional behavior of short peptide motifs.
Article
Endocrinology & Metabolism
Shelley R. Winn, Sandra Dudley, Tanja Scherer, Nicole Rimann, Beat Thoeny, Sydney Boutros, Destine Krenik, Jacob Raber, Cary O. Harding
Summary: The study found that lifelong weekly pegvaliase treatment can prevent cognitive deficits associated with hyperphenylalaninemia in mice, particularly with significant improvements in overall growth of the mice with early treatment. However, cognitive deficits may reappear after discontinuation of treatment, especially when treatment is stopped in adulthood.
MOLECULAR GENETICS AND METABOLISM
(2022)
Article
Chemistry, Analytical
Yuting Jin, Rongfang Yan, Shuo Wang, Xianghong Wang, Xuemei Zhang, Yiwei Tang
Summary: A novel fluorescence platform was developed for the determination of enrofloxacin, which utilized FDNP-cDNA and Fe3O4-Apt modified nanoparticles. The platform demonstrated good selectivity and sensitivity.
Article
Chemistry, Analytical
Skaidre Jankovskaja, Maxim Morin, Anna Gustafsson, Chris D. Anderson, Boglarka Lehoczki, Johan Engblom, Sebastian Bjorklund, Meinda Rezeli, Gyorgy Marko-Varga, Tautgirdas Ruzgas
Summary: This study assessed various sampling approaches for tryptophan and kynurenine and found that the phenylalanine/tryptophan ratio may be a possible alternative biomarker for non-invasive skin cancer detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Psychology, Biological
Xueting Zhang, Kazufumi Yoshihara, Noriyuki Miyata, Tomokazu Hata, Altanzul Altaisaikhan, Shu Takakura, Yasunari Asano, Satoshi Izuno, Nobuyuki Sudo
Summary: The study found that a lack of dietary precursors of important neurotransmitters – tryptophan, tyrosine, and phenylalanine, resulted in decreased food intake and body weight, increased activity levels, and reduced concentrations of monoamines in the brain.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Pharmacology & Pharmacy
Zakaria Hafidi, Lourdes Perez, Mohammed El Achouri, Ramon Pons
Summary: Cationic surfactants based on phenylalanine and tryptophan were synthesized using renewable raw materials and a green synthetic procedure. The synthesis, acid-base equilibrium, aggregation properties, and antibacterial activity of these surfactants were investigated. The surfactants showed promising antibacterial efficacy and had a high affinity for DPPC bilayers, although their antibacterial activity was reduced when incorporated in vesicles.
Article
Pharmacology & Pharmacy
Lourdes Perez, Maria Teresa Garcia, Aurora Pinazo, Edgar Perez-Matas, Zakaria Hafidi, Elena Bautista
Summary: Cationic surfactants have been explored for their potential as drug vehicles, gene therapy tools, and antimicrobial agents. This study synthesized a library of amino acid-based surfactants and systematically modified their head group architecture and hydrophobic moiety. The structure-activity relationships established here may offer insights for designing effective biodegradable antimicrobial materials.
Article
Chemistry, Multidisciplinary
Kai Cui, Alexander V. Soudackov, Matthew C. Kessinger, Jeremiah Xu, Gerald J. Meyer, Sharon Hammes-Schiffer
Summary: The pH dependence of proton-coupled electron transfer (PCET) reactions can be explained by a general, multichannel kinetic model. Multiple sequential and concerted PCET channels, involving different forms of redox species, contribute to a weak pH dependence of PCET apparent rate constants. This model has been used to understand the weak pH dependence observed in an electrochemical PCET reaction involving a ruthenium-based water oxidation catalyst.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Igor Khmelinskii, Vladimir Makarov
Summary: ATP production in Saccharomyces cerevisiae cells is accelerated by both direct and indirect mitochondrial photo-activation (MPA). Direct MPA directly activates cytochrome c, while indirect MPA uses electronically excited cytochrome c generated by energy transfer from a Co/BN film to activate ATP synthesis. The findings support the hypothesis of indirect MPA in ATP production in the vertebrate retina.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Igor Khmelinskii, Vladimir I. Makarov
Summary: This article discusses different theoretical approaches to model mitochondrial swelling dynamics. It concludes that simple phenomenological kinetic models have limitations in terms of accuracy, while biophysical models that include mechanical properties of the inner mitochondrial membrane can model the transition to irreversible swelling.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
(2022)
Article
Spectroscopy
Anna Golczak, Malgorzata Insinska-Rak, Amirali Davoudpour, Daban Hama Saeed, Petra Menova, Viktor Mojr, Radek Cibulka, Igor Khmelinskii, Lucyna Mrowczynska, Marek Sikorski
Summary: The spectral and photophysical properties of two four-ring alloxazine derivatives, 1a and 1b, were investigated. The research found that 1a did not undergo excited-state proton transfer reactions in the presence of acetic acid as a catalyst. The quenching effect of acetic acid on the fluorescence of 1a was also studied. Furthermore, fluorescence lifetime imaging microscopy (FLIM) using 1a and 1b as fluorescence probes was applied to in vitro human red blood cells (RBCs) to evaluate their effects on the redox properties of RBCs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biology
Igor Khmelinskii, Vladimir Makarov
Summary: A theoretical biophysical model for analyzing mitochondrial swelling dynamics in vivo, capable of reproducing the transition from reversible to irreversible dynamics, is reported. Different results were obtained compared to the in vitro model.
Article
Food Science & Technology
Malgorzata Muzolf-Panek, Anna Gliszczynska-Swiglo
Summary: This study used response surface methodology to determine the optimal conditions for extracting phenolic compounds from black seed and obtained highly accurate models.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2022)
Article
Materials Science, Ceramics
Adam Kubiak, Marta Wojcieszak, Hubert Fuks, Elzbleta Gabala, Katarzyna Materna, Marek Sikorski, Teofil Jesionowski
Summary: A new microwave-assisted process was used for the crystallization of titania nanoparticles. The microwave crystallization is environmentally friendly, energy efficient, and has a short process time, resulting in pure materials without surface defects. The physicochemical properties of the synthesized TiO2 nanomaterials strongly depend on the microwave crystallization temperature.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Applied
Katarzyna Wlodarska, Anna Gliszczynska-Swiglo, Ewa Sikorska
Summary: The concentrations of phenolic acids and flavonoids were measured in different types of commercial apple juices using high-performance liquid chromatography. Chlorogenic acid was the dominant polyphenolic compound, followed by flavan-3-ols. Pattern recognition techniques were used to classify the juices based on their polyphenolic profiles, with satisfactory discrimination between juices made from concentrate and not from concentrate. HPLC combined with pattern recognition methods is a promising tool for grouping commercially available apple juices based on their polyphenolic profile.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Organic
Radek Cibulka, Marek Sikorski, Tomas Tobrman, Marek Cubinak, Naisargi Varma, Petr Oeser, Adam Pokluda, Tetiana Pavlovska
Summary: Palladium-catalyzed Suzuki reactions of brominated flavin derivatives are an effective method for synthesizing a broad range of 7/8-arylflavins. Introducing aryl/heteroaryl groups through direct C-C bond formation can tune the photophysical properties of flavin derivatives, leading to bathochromic shifts in absorption spectra and prolonged fluorescence lifetimes. Additionally, arylation of flavin derivatives reduces their ability to generate singlet oxygen.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Igor Khmelinskii, Vladimir Makarov
Summary: This study investigates the optical and electrical properties of Co/Ni bilayer nanofilms, revealing their semiconductor behavior describable using Schottky diode theory. These semiconducting properties make them suitable for special low-temperature low-consumption electronic devices.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2023)
Article
Multidisciplinary Sciences
Adam Kubiak, Naisargi Varma, Marek Sikorski
Summary: This paper proposes a novel LED-assisted deposition method for platinum nanoparticles on the titania surface. The process is supported by a UV-LED solution and utilizes two light sources with different wavelengths and power. The resulting TiO2-Pt material shows nano-platinum particles deposited on the titanium dioxide surface, and a decrease in luminescence intensity.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Physical
Igor Khmelinskii, Vladimir I. Makarov
Summary: Low-energy exciton transfer was observed in Muller cell intermediate filaments (IFs) from porcine retina. The transfer of these excitons to human alcohol dehydrogenase (ADH1A) enzyme accelerated the rate of ethanol oxidation. This suggests that IFs may transmit energy to enzyme molecules in vivo, providing a control mechanism for enzymatic reactions. The indirect activation of the ADH1A molecule in the IF...ADH1A...NAD...EtOH complex occurred through energy transfer from the 4 μm IR exciton.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Physical
Adam Kubiak, Anna Grzegorska, Elzbieta Gabala, Joanna Zembrzuska, Miroslaw Szybowicz, Hubert Fuks, Anna Szymczyk, Anna Zielinska-Jurek, Marek Sikorski, Teofil Jesionowski
Summary: A novel method incorporating carbon into the structure of titania has been proposed using a widely used and cheap surfactant, cetyltrimethylammonium bromide. The method allows for the synthesis of TiO2-C nanostructures with carbon deposited either on the surface or between the TiO2 nanoparticles. The research is innovative in the design of cheap LED solutions and facile synthesis of TiO2-C for energy-saving photocatalytic systems.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Izabela Buniowska, Norbert Wronski, Malgorzata Insinska-Rak, Marek Sikorski, Agnieszka Wolnicka-Glubisz
Summary: This study compared the effects of 3MeTARF and riboflavin on A431 cancer cells under irradiation. The results showed that 3MeTARF more effectively activated MAPK and induced cell death in skin cancer cells, suggesting its therapeutic potential in photodynamic oxidation processes.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Malgorzata Insinska-Rak, Anna Golczak, Mateusz Gierszewski, Zubair Anwar, Volodymyr Cherkas, Dorota Kwiatek, Ewa Sikorska, Igor Khmelinskii, Gotard Burdzinski, Radek Cibulka, Lucyna Mrowczynska, Jacek Lukasz Kolanowski, Marek Sikorski
Summary: This article reports the photophysical properties of 5-deazaalloxazine (1a) in different solvents. It is found that the triplet excited states of 1a in water and acetonitrile have microsecond lifetimes, and 1a can efficiently generate singlet oxygen under oxygen conditions. In addition, experiments using human red blood cell models show that 1a has antioxidant and cytotoxic activities.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
