Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes

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Nanoparticulate systems for brain delivery of drugs

(2012) Jörg Kreuter   ADVANCED DRUG DELIVERY REVIEWS

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Effects of Silver Nanoparticles on Primary Mixed Neural Cell Cultures: Uptake, Oxidative Stress and Acute Calcium Responses

(2012) Andrea Haase et al.   TOXICOLOGICAL SCIENCES

Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells

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Uptake and intracellular localization of submicron and nano-sized SiO2 particles in HeLa cells

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Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

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Internal benchmarking of a human blood–brain barrier cell model for screening of nanoparticle uptake and transcytosis

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State of the art of nanocrystals – Special features, production, nanotoxicology aspects and intracellular delivery

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Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

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Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics

(2011) Anna Salvati et al.   Nanomedicine-Nanotechnology Biology and Medicine

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

(2011) Carsten Schleh et al.   Nanotoxicology

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

(2011) A. Sood et al.   Nature Nanotechnology

Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population

(2011) Jong Ah Kim et al.   Nature Nanotechnology

Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines

(2011) Tiago dos Santos et al.   PLoS One

Rutile TiO2 particles exert size and surface coating dependent retention and lesions on the murine brain

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Cytokine signaling in the human brain capillary endothelial cell line hCMEC/D3

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Time and space resolved uptake study of silicananoparticles by human cells

(2010) Kayle Shapero et al.   Molecular BioSystems

Degradability of superparamagnetic nanoparticles in a model of intracellular environment: follow-up of magnetic, structural and chemical properties

(2010) Michael Lévy et al.   NANOTECHNOLOGY

Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line

(2010) Mariana G. Bexiga et al.   Nanotoxicology

Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

(2010) Valerian E. Kagan et al.   Nature Nanotechnology

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones

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Nanoparticles and the Brain: Cause for Concern?

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Nanoparticles can cause DNA damage across a cellular barrier

(2009) Gevdeep Bhabra et al.   Nature Nanotechnology

Structure and function of the blood–brain barrier

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