Journal
ANALYST
Volume 138, Issue 1, Pages 107-110Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2an36003a
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Funding
- National Natural Science Foundation of China [21175086]
- Natural Science Foundation of Shanxi Province [2010021010-2]
- China Postdoctoral Science Foundation [201104651, 20100471581]
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A simple method of room temperature phosphorescence is proposed for the determination of propranolol enantiomeric composition based on beta-cyclodextrin as the chiral host and bromocyclohexane as the heavy atom. Enantiomeric complexes are formed upon binding of the propranolol enantiomer to beta-cyclodextrin, and the sign of the resultant phosphorescence signals allows for the identity of the propranolol enantiomers configuration to be determined successfully.
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