Article
Biochemistry & Molecular Biology
Albert Layo Costa de Assis, Patricia de Araujo Rodrigues, Selene Maia de Morais, Ana Livya Moreira Rodrigues, Jessica Maria Pessoa Gomes, Tyciane de Souza Nascimento, Alfaete Vieira Oliveira, Mayara Sandrielly Soares de Aguiar, Geanne Matos de Andrade
Summary: This study evaluated the cytoprotective activity of B. sericea ethanolic extract (BSEE) in a Parkinson's disease cell model. The results showed that BSEE had antioxidant and anti-apoptotic effects, suggesting its potential as a cytoprotective agent for Parkinson's disease.
NEUROCHEMICAL RESEARCH
(2023)
Article
Plant Sciences
Laiza S. Biano, Alan S. Oliveira, David N. Palmeira, Luis Andre Silva, Ricardo L. C. De Albuquerque-Junior, Marcelo C. Duarte, Cristiane B. Correa, Renata Grespan, Josemar S. Batista, Enilton A. Camargo
Summary: The ethanol extract of Leonurus sibiricus aerial parts shows gastroprotective effects in mice, potentially through involvement of oxidative stress, NP-SH, KATP channels, and mucus production.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Joao Francisco Camara Neto, Matheus da Silva Campelo, Gilberto Santos Cerqueira, Joao Antonio Leal de Miranda, Jhonyson Arruda Carvalho Guedes, Raimundo Rafael de Almeida, Sandra de Aguiar Soares, Nilce Viana Gramosa, Guilherme Juliao Zocolo, Icaro Gusmao Pinto Vieira, Nagila Maria Pontes Silva Ricardo, Maria Elenir Nobre Pinho Ribeiro
Summary: This study aimed to characterize the chemical profile of Agaricus blazei Murill extract and evaluate its gastroprotective effect. The results showed that the extract had antioxidant activity and could protect the gastric mucosa.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Miriam Sannomiya, Clenilson Martins Rodrigues, Giovanna Castro Araujo Oliveira, Juliana Cajado Souza Carvalho, Leticia Serafim da Costa, Cristina de Castro Spadari, Marcelo Jose Pena Ferreira, Wagner Vilegas, Kelly Ishida
Summary: The study revealed that the leaves of Byrsonima fagifolia are rich in galloylquinic acid derivatives, which exhibit antifungal activity and low toxicity.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Miriam Sannomiya, Clenilson Martins Rodrigues, Giovanna Castro Araujo Oliveira, Juliana Cajado Souza Carvalho, Leticia Serafim da Costa, Cristina de Castro Spadari, Marcelo Jose Pena Ferreira, Wagner Vilegas, Kelly Ishida
Summary: The major compounds in the leaves of Byrsonima fagifolia were identified as galloylquinic acid derivatives, which exhibited antifungal activity and low toxicity.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Elizabeth Arlen Pineda-Pena, David Capistran-Amezcua, Adelfo Reyes-Ramirez, Santiago Xolalpa-Molina, Aracely Evangelina Chavez-Pina, Mario Figueroa, Andres Navarrete
Summary: The study investigated the gastroprotective effect of Caesalpinia coriaria pod extract against gastric ulcer models induced by ethanol and indomethacin, as well as its anti-inflammatory and antioxidative activities. The results showed that the extract exhibited anti-inflammatory and antioxidant properties, and gallic acid derivatives may be the main active compounds responsible for its actions.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Shu Fu, Jiamei Chen, Chen Zhang, Jinfeng Shi, Xin Nie, Yichen Hu, Chaomei Fu, Xiaofang Li, Jinming Zhang
Summary: Experimental results showed that the 20% ethanol extract of Periplaneta americana L. exerted gastroprotective effects by protecting gastric mucosa, suppressing inflammatory cytokines, and downregulating the MyD88/NF-κB pathway.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Plant Sciences
Ismaila Yada Sudi, Maryam Usman Ahmed, Bulus Adzu
Summary: The study investigated the chemical constituents and gastroprotective activity of Sphaeranthus senegalensis DC hydroethanolic extract. The results showed that the extract contained phenolics and flavonoids, was safe for oral administration, and exerted significant gastroprotective effects through gastroprotection, anti-secretory, and antioxidant activities.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Edilane Rodrigues Dantas De Araujo, Gerlane Coelho Bernardo Guerra, Anderson Wilbur Lopes Andrade, Julia Morais Fernandes, Valeria Costa Da Silva, Emanuella De Arago Tavares, Aurigena Antunes De Araujo, Raimundo Fernandes de Araujo Junior, Silvana Maria Zucolotto
Summary: The study found that Bryophyllum pinnatum extract demonstrated a significant healing effect on gastric ulcers, improving antioxidant defense system, reducing inflammation, and having cytoprotective effects. Quercetin 3-O-alpha-L-arabinopyranosyl-(1 -> 2)-O-alpha-L-rhamnopyranoside was identified as the major active compound.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Mengqi Li, Renzhi Lv, Xiaomeng Xu, Qi Ge, Songyi Lin
Summary: T. matsutake peptides attenuate ethanol-induced inflammatory responses and apoptosis by suppressing NF-kappa B signaling activation, thereby enhancing gastric epithelial barrier functions.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Food Science & Technology
Xiaoai Chen, Dan Yang, Qun Wang, Aimei Zhou
Summary: This study investigated the protective mechanism and main components of finger citron pickled products (FCPP) aqueous extract on gastric mucosa through in vitro and in vivo experiments. The results showed that FCPP aqueous extract could promote cell repair and secrete TFF2, while inhibiting the secretion of TNF-α in damaged cells. It also exhibited good antioxidant and anti-inflammatory properties.
Article
Biochemistry & Molecular Biology
Peerachit Tonchaiyaphum, Warangkana Arpornchayanon, Parirat Khonsung, Natthakarn Chiranthanut, Pornsiri Pitchakarn, Puongtip Kunanusorn
Summary: This study evaluated the gastroprotective activities of black rice bran ethanol extract (BRB) from the Thai black rice variety Hom Nil and found that its mechanism of action may be through antioxidant activity. BRB inhibited ulcer formation in gastric ulcer models, but did not affect gastric wall mucus or acidity. However, it could normalize tissue MDA levels through radical scavenging activity.
Article
Plant Sciences
Emmanuel Kofi Kumatia, Frederick Ayertey, Regina Appiah-Opong, Godfrey Kyaakyile Bagyour, Kenneth Opare Asare, Valentine Chi Mbatcho, Jonathan Dabo
Summary: The study aimed to standardize the ethanol leaf extract of Annickia polycarpa and investigate its anti-malaria properties and effects on hematological indices. Results showed that APLE exhibited significant anti-malarial activity, reversed physiological alterations caused by malaria, and demonstrated important therapeutic effects in mice.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Juan Luo, Jie Hu, Meiling Zhang, Yue Zhang, Jiashu Wu, Jinjun Cheng, Huihua Qu, Hui Kong, Yan Zhao
Summary: Nelumbinis Rhizomatis Nodus carbon dots (NRN-CDs) show significant gastroprotective effects on ethanol-induced gastric ulcers in rats, potentially through the regulation of oxidative stress and inflammatory factors. NRN-CDs could be developed as a promising drug for the treatment of gastric ulcers.
Article
Biochemistry & Molecular Biology
Rim Ben Mansour, Raja Serairi Beji, Hanen Wasli, Sami Zekri, Riadh Ksouri, Wided Megdiche-Ksouri, Susana M. Cardoso
Summary: Microencapsulated Myrtus communis L. essential oil showed significant gastroprotective activity in a rat model of gastric ulcer, potentially due to its anti-inflammatory and antioxidant properties.
