Article
Medicine, General & Internal
Ru-Ying Pang, Yao-Hua Shen, Xiao-Qin Jin, Hai-Feng Xu, Yang Wang, Bin-Xiang Zhu, Su-Feng Lin, Fei Xiao
Summary: This study evaluated the efficacy of combining different doses of dexmedetomidine or fentanyl with ropivacaine for labor analgesia. The results showed that dexmedetomidine (0.3 and 0.4 μg/ml) reduced the amount of ropivacaine administered and minimized opioid-related side effects. This study provided evidence for the potential of dexmedetomidine as an alternative to opioids for labor analgesia, and further research is needed to confirm its benefits.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Ming Yan, Qiao Wang, Yufeng Zhang, Jing Zhou, Enhui Cui, Jian Sun
Summary: This study demonstrates that the dural puncture epidural technique combined with programmed intermittent epidural bolus mode for labor analgesia provides faster analgesia, reduces the consumption of ropivacaine, and decreases the incidence of incomplete analgesia and intrapartum fever compared to conventional methods.
Article
Anesthesiology
H. S. Tan, C. W. Tan, R. Sultana, H. Y. Chen, T. Chua, N. Rahman, M. Gandhi, A. T. H. Sia, B. L. Sng
Summary: There is conflicting evidence regarding the association between epidural labour analgesia and risk of postpartum depression. This study found no significant difference in the risk of postpartum depression between patients who received epidural labour analgesia and those who utilized non-epidural analgesic modalities.
Article
Anesthesiology
E. Roofthooft, N. Filetici, M. Van Houwe, P. Van Houwe, A. Barbe, S. Fieuws, S. Rex, C. A. Wong, M. Van de Velde
Summary: The aim of neuraxial analgesia is to achieve excellent pain relief with the fewest adverse effects. The programmed intermittent epidural bolus technique has been introduced as a maintenance technique for epidural analgesia. Compared to patient-controlled epidural analgesia without background infusion, programmed intermittent epidural bolus is associated with less breakthrough pain, lower pain scores, higher local anaesthetic consumption, and comparable motor block.
Article
Anesthesiology
Shirley Andrade Santos, Hermann Dos Santos Fernandes, Fernando Souza Nani, Andreza Gonzaga Bartilotti, Rossana Pulcineli Vieira Francisco, Maria Jose Carvalho Carmona, Fernando Bliacheriene, Joaquim Edson Vieira
Summary: This study compared the effects of combined spinal-epidural technique (CSE) and epidural analgesia (EA) on catecholamines levels, uterine tone, and fetal heart rate. The results showed no significant differences in catecholamines levels between the two groups, suggesting that the theory of catecholamines decrease may not be valid for modern labor analgesia techniques.
ANAESTHESIA CRITICAL CARE & PAIN MEDICINE
(2022)
Article
Obstetrics & Gynecology
Hanna Oommen, Tor Oddbjorn Tveit, Leif T. Eskedal, Rachel Myr, David M. Swanson, Ingvild Vistad
Summary: The study found that the use of fentanyl during labor can result in breastfeeding difficulties, especially with EDA fentanyl and IV+EDA fentanyl. When IV fentanyl doses exceeded 200 μg, there was a reduction in exclusive breastfeeding and spontaneous suckling rates, along with an increase in breastfeeding problems.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Anesthesiology
Wiebke Falk, Anders Magnuson, Christina Eintrei, Ragnar Henningsson, Par Myrelid, Peter Matthiessen, Anil Gupta
Summary: This study found no significant difference in disease-free survival at 5 years between patients undergoing colorectal cancer surgery with thoracic epidural analgesia (TEA) versus patient-controlled intravenous analgesia (PCA) with morphine. While TEA provided better pain relief during the first 24 hours postoperatively, there were no other differences in outcomes compared to PCA.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Health Care Sciences & Services
Yu Wei, Yilong Wang, Yanhong Zhao, Chaomin Wu, Henry Liu, Zeyong Yang
Summary: It is unclear whether a high dosage of PCEA with a low dosage of background infusion during labor can be a safe and effective application.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Anesthesiology
Jennifer Bourges, Clement Gakuba, Felipe Plass, Jean-Louis Gerard, Therese Simone, Jean-Luc Hanouz
Summary: In nulliparous women over 35 weeks of gestational age, adding a programmed intermittent epidural bolus (PIEB) to patient-controlled epidural analgesia (PCEA) resulted in higher hourly consumption of levobupivacaine compared to PCEA alone. However, there were no significant differences between the two groups in terms of secondary outcomes.
ANAESTHESIA CRITICAL CARE & PAIN MEDICINE
(2021)
Article
Anesthesiology
Christoph Klivinyi, Gudrun Rumpold-Seitlinger, Christian Dorn, Larissa Sampl, Nikki Sivro, Kordula Lang-Illievich, Sabine Fleck, Sylvia Farzi, Helmar Bornemann-Cimenti
Summary: The study found that intraoperative physostigmine did not affect opioid consumption but increased mechanical pain thresholds, reduced hyperalgesia distance and wind-up ratios, and lowered postoperative pain scores. Patients in the physostigmine group also reported lower Pain Disability Index and higher satisfaction with pain control after 3 months, suggesting that physostigmine has antihyperalgesic effects and can attenuate sensitisation processes.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Medicine, General & Internal
Qinjun Chu, Yan Sun, Lihui Bai, Yafan Bai, Dongqing Zhang, Ping Zheng, Xiaogao Jin
Summary: This study aimed to compare the differences in inducing fever after delivery between epidural and combined spinal-epidural analgesia. The results showed no significant differences in the fever rate and fever latent period between the two methods. Therefore, further research is needed to confirm the similarity between epidural and combined spinal-epidural analgesia in the development of postpartum fever.
FRONTIERS IN MEDICINE
(2022)
Article
Nursing
Maria del Carmen Carrascosa, Araceli Navas, Catalina Artigues, Silvia Ortas, Elena Portells, Aina Soler, Miquel Bennasar-Veny, Alfonso Leiva
Summary: The study found that moderate aquatic aerobic exercise during pregnancy did not significantly affect the use of epidural analgesia during labor, but it did reduce labor pain. The intervention was also deemed safe for both pregnant women and their newborns.
Article
Anesthesiology
Harald Lenz, Lars O. Hoiseth, Marlin Comelon, Tomas Draegni, Leiv A. Rosseland
Summary: The study showed that inhaled methoxyflurane and IV fentanyl at 25 μg have similar analgesic effects for acute pain relief, both significantly better than placebo. IV fentanyl at 50 μg demonstrated superior analgesia compared to methoxyflurane.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Anesthesiology
Yujie Song, Weijia Du, Shuangqiong Zhou, Yao Zhou, Yibing Yu, Zhendong Xu, Zhiqiang Liu
Summary: In labor analgesia, the DPE technique with PIEB mode showed faster onset, reduced anesthetic drug consumption, and no increase in maternal or neonatal side effects compared to other techniques.
ANESTHESIA AND ANALGESIA
(2021)
Article
Medicine, General & Internal
Nadir Sharawi, Matthew Williams, Waseem Athar, Caroline Martinello, Kyle Stoner, Cameron Taylor, Nan Guo, Pervez Sultan, Jill M. Mhyre
Summary: This study aimed to compare the anesthesia effect of dural-puncture epidural (DPE) and standard epidural in cesarean delivery. The results showed that DPE technique resulted in a faster onset and better quality of anesthesia compared to the standard epidural technique. Therefore, in scheduled cesarean delivery, the DPE technique can provide better anesthesia effect.
Article
Public, Environmental & Occupational Health
Philippa Davie, Debra Bick, Sergio A. Silverio, Joseph Chilcot
Summary: This study examines whether the perceptions and practices of infant feeding are different among women who give birth to larger birthweight infants. The results suggest that larger infant birthweight may be a protective factor against breastfeeding difficulties, alleviating maternal concerns, but not reducing the demands of breastfeeding.
PSYCHOLOGY & HEALTH
(2023)
Review
Nursing
Yan-Shing Chang, Sarah Beake, Joyce Kam, Kris Yuet-Wan Lok, Debra Bick
Summary: This study aimed to examine and synthesise qualitative evidence on the views and experiences of women, peer supporters, and healthcare professionals regarding breastfeeding peer support. The findings indicated that breastfeeding peer support increased women's self-esteem and confidence while reducing social isolation. Peer supporters valued the experience, which gave them a sense of purpose and confidence, and felt good about helping the women they supported. Women appreciated peer supporters who showed care, spent time with them, shared experiences, provided realistic information, and offered practical and emotional support. Embedding peer supporters in healthcare systems, working alongside healthcare professionals, and building trustful relationships could be an effective strategy to reduce tensions between them.
Article
Obstetrics & Gynecology
George Daskalakis, Vasilios Pergialiotis, Magnus Domelloef, Harald Ehrhardt, Gian Carlo Di Renzo, Esin Koc, Ariadne Malamitsi-Puchner, Marian Kacerovsky, Neena Modi, Andrew Shennan, Diogo Ayres-de-Campos, Elko Gliozheni, Kristiina Rull, Thorsten Braun, Artur Beke, Katarzyna Kosinska-Kaczynska, Ana Luisa Areia, Simona Vladareanu, Tanja Premru Srsen, Thomas Schmitz, Bo Jacobsson
Summary: Corticosteroids should be given to pregnant women between 24 and 33 weeks of gestation, when preterm birth is expected within the next seven days, as they have been proven to reduce neonatal mortality and morbidity. In some cases, this period can be extended up to 34(+6) weeks. It is recommended to administer the corticosteroids within 7 days of delivery, even with a single dose, to improve neurodevelopmental outcome. Betamethasone or dexamethasone can be used as corticosteroids.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Cristina Fernandez Turienzo, Louise H. Hull, Kirstie Coxon, Mary Bollard, Pauline Cross, Paul T. Seed, Andrew H. Shennan, Jane Sandall
Summary: This study evaluated the implementation and effectiveness of the POPPIE care model, which combines midwifery continuity of care with a specialist obstetric clinic, for pregnant women at risk of preterm birth in London, UK. The results showed that the POPPIE model was feasible, acceptable, and implemented with high fidelity and sustainability. The importance of this study lies in providing a new care model for improving the care of pregnant women at risk of preterm birth.
Review
Endocrinology & Metabolism
Lily Hopkins, Angus Forbes, Janet E. Anderson, Debra Bick, Anna Brackenridge, Anita Banerjee, Mark Chamley, Kia-Chong Chua, Angela C. Flynn, Katherine Hunt, Helen R. Murphy, Helen Rogers, Sara L. White, Kirsty Winkley, Rita Forde
Summary: This study aims to examine the content and impact of interventions to increase the uptake of pre-pregnancy care for women with type 2 diabetes. The study found that previous interventions had a limited impact on improving pre-pregnancy care uptake in women with type 2 diabetes.
Review
Nutrition & Dietetics
Natasha Baker, Debra Bick, Louise Bamber, Claire A. Wilson, Louise M. Howard, Ioannis Bakolis, Tayana Soukup, Yan-Shing Chang
Summary: Women with severe mental illness face challenges in initiating and maintaining breastfeeding compared to women without mental illness. This systematic review examines infant feeding outcomes, experiences and support, interventions, and healthcare professionals' attitudes towards supporting breastfeeding in women with SMI.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Medicine, General & Internal
Ioannis Gallos, Adam Devall, James Martin, Lee Middleton, Leanne Beeson, Hadiza Galadanci, Fadhlun Alwy Al-beity, Zahida Qureshi, G. Justus Hofmeyr, Neil Moran, Sue Fawcus, Lumaan Sheikh, George Gwako, Alfred Osoti, Ashraf Aswat, Kristie-Marie Mammoliti, Kulandaipalayam N. Sindhu, Marcelina Podesek, Isobelle Horne, Rebecca Timms, Idnan Yunas, Jenipher Okore, Mandisa Singata-Madliki, Edna Arends, Aminu A. Wakili, A. Mwampashi, Sidrah Nausheen, Shah Muhammad, Pallavi Latthe, Cherrie Evans, Shahinoor Akter, Gillian Forbes, David Lissauer, Shireen Meher, Andrew Weeks, Andrew Shennan, Anne Ammerdorffer, Eleanor Williams, Tracy Roberts, Mariana Widmer, Olufemi T. Oladapo, Fabiana Lorencatto, Meghan A. Bohren, Suellen Miller, Fernando Althabe, Metin Gulmezoglu, Jeffrey M. Smith, Karla Hemming, Arri Coomarasamy
Summary: This study aimed to evaluate a multicomponent clinical intervention for early detection and treatment of postpartum hemorrhage. The results showed that the use of a blood-collection drape and treatment bundle reduced the risk of severe postpartum hemorrhage and improved detection and adherence to treatment.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Medicine, General & Internal
Clare Macdonald, Becky MacGregor, Sarah Hillman, Christine MacArthur, Debra Bick, Beck Taylor
Summary: This qualitative systematic review aims to explore the views and experiences of general practitioners (GPs) regarding their role in postnatal care. The study findings indicate that GPs perceive postnatal care as an opportunity for relationship building and health promotion. Addressing organizational barriers can positively influence GPs' motivation to provide optimal care.
Article
Medicine, General & Internal
Fiona E. McLardie-Hore, Della A. Forster, H. L. McLachlan, Touran Shafiei, Lisa H. Amir, Mary-Ann Davey, Heather Grimes, Lisa Gold
Summary: The study aimed to evaluate the effectiveness of a proactive telephone-based peer support breastfeeding intervention. The results showed that participants who received the intervention had higher breastfeeding rates at 6 months compared to those who received standard care. Considering the significant improvement in breastfeeding outcomes, this intervention is potentially cost-effective.
Article
Audiology & Speech-Language Pathology
Tristan Nickless, Lisa Gold, Richard Dowell, Bronwyn Davidson
Summary: This study investigated the perceptions of speech-language pathologists in accessing public funding models for children and young persons with communication and swallowing needs in independent practice in Australia. The research findings revealed that the current funding provisions do not align with evidence-based speech-language pathology management, highlighting the need for equitable and efficient funding that is acceptable to stakeholders. Further research is recommended to identify PFMs that facilitate access to speech-language pathology services and promote optimal outcomes.
INTERNATIONAL JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2023)
Article
Nursing
Sergio A. Silverio, Amanda Bye, Rosanna Hildersley, Olivia Chingara, Yan-Shing Chang, Debra Bick
Summary: Despite the long-term implications for maternal health, there is little focus on women's care and recovery following pregnancy complicated by hypertensive disorders of pregnancy (HDP). This study explored women's experiences of birth-recovery up to 12 months following HDP, and identified the need for tailored postnatal care and ongoing support from healthcare professionals.
Article
Medicine, Research & Experimental
Shawn Walker, Emma Spillane, Kate Stringer, Amy Meadowcroft, Tisha Dasgupta, Sian M. Davies, Jane Sandall, Andrew Shennan
Summary: OptiBreech Care is a feasible approach for providing care to breech presentation at term, with the goal of supporting physiologic breech birth attended by trained professionals. The study aimed to assess the feasibility of implementing OptiBreech team care prior to a planned pilot randomized controlled trial.
PILOT AND FEASIBILITY STUDIES
(2023)
Article
Obstetrics & Gynecology
Katy Kuhrt, Anastasia Martin, Lusako Paskali Mwaikasu, Andrew Shennan
Summary: Access to training and education in novel surgical and medical techniques is challenging in low-and-middle income settings, but video-based education tools can provide cost-effective and sustainable solutions, allowing clinicians in remote areas to develop new skills and improve patient care quality. A successful case in Tanzania showed how a clinician performed a transabdominal cerclage after studying a video developed by our team, resulting in successful pregnancy outcomes for two patients with poor obstetric histories. Video is a versatile medium that should be further integrated into surgical training curricula globally.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Medicine, General & Internal
Ioannis Gallos, Adam Devall, James Martin, Lee Middleton, Leanne Beeson, Hadiza Galadanci, Fadhlun Alwy Al-beity, Zahida Qureshi, G. Justus Hofmeyr, Neil Moran, Sue Fawcus, Lumaan Sheikh, George Gwako, Alfred Osoti, Ashraf Aswat, Kristie-Marie Mammoliti, Kulandaipalayam N. Sindhu, Marcelina Podesek, Isobelle Horne, Rebecca Timms, Idnan Yunas, Jenipher Okore, Mandisa Singata-Madliki, Edna Arends, Aminu A. Wakili, Ard Mwampashi, Sidrah Nausheen, Shah Muhammad, Pallavi Latthe, Cherrie Evans, Shahinoor Akter, Gillian Forbes, David Lissauer, Shireen Meher, Andrew Weeks, Andrew Shennan, Anne Ammerdorffer, Eleanor Williams, Tracy Roberts, Mariana Widmer, Olufemi T. Oladapo, Fabiana Lorencatto, Meghan A. Bohren, Suellen Miller, Fernando Althabe, Metin Gulmezoglu, Jeffrey M. Smith, Karla Hemming, Arri Coomarasamy
Summary: Early detection and bundled treatment of postpartum hemorrhage led to a lower risk of severe complications or death compared to usual care among patients undergoing vaginal delivery.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Letter
Obstetrics & Gynecology
Jenny Carter, Naomi Carlisle, Anna David, Jane Sandall, Paul Seed, Andrew Shennan, Rachel Tribe, Helena Watson
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
