Inhibitors of amino acids biosynthesis as antifungal agents

Inhibition of Nucleotide Biosynthesis Potentiates the Antifungal Activity of Amphotericin B

(2014) Dithi Banerjee et al.   PLoS One

Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents

(2013) Daryl L. Richie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A biochemical correlate of dimorphism in a zygomycete Benjaminiella poitrasii: characterization of purified NAD-dependent glutamate dehydrogenase, a target for antifungal agents

(2013) C. V. Joshi et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Synthesis and biological evaluation of potential threonine synthase inhibitors: Rhizocticin A and Plumbemycin A

(2013) Mathias Gahungu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus

(2013) Nicola Beckmann et al.   PLoS One

Homoisocitrate dehydrogenase fromCandida albicans: properties, inhibition, and targeting by an antifungal pro-drug

(2012) Iwona Gabriel et al.   FEMS YEAST RESEARCH

Cystathionine gamma-synthase is essential for methionine biosynthesis in Fusarium graminearum

(2012) Jing Fu et al.   Fungal Biology

Sulfonylureas Have Antifungal Activity and Are Potent Inhibitors of Candida albicans Acetohydroxyacid Synthase

(2012) Yu-Ting Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antifungal Activity of Homoaconitate and Homoisocitrate Analogs

(2012) Maria Milewska et al.   MOLECULES

The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

(2012) Jason D. Oliver et al.   PLoS One

Allosteric pathways in imidazole glycerol phosphate synthase

(2012) I. Rivalta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

δ1-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

(2011) Giuseppe Forlani et al.   AMINO ACIDS

Identification and Characterization of New Inhibitors of Fungal Homoserine Kinase

(2011) Gianfranco De Pascale et al.   CHEMBIOCHEM

Anti-virulence Strategy against Brucella suis: Synthesis, Biological Evaluation and Molecular Modeling of Selective Histidinol Dehydrogenase Inhibitors

(2011) Marie-Rose Abdo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structure based design of novel inhibitors for histidinol dehydrogenase from Geotrichum candidum

(2010) Sonia Pahwa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biosynthesis of Rhizocticins, Antifungal Phosphonate Oligopeptides Produced by Bacillus subtilis ATCC6633

(2010) Svetlana A. Borisova et al.   CHEMISTRY & BIOLOGY

Fungal Homoserine Kinase (thr1Δ) Mutants Are Attenuated in Virulence and Die Rapidly upon Threonine Starvation and Serum Incubation

(2010) Joanne M. Kingsbury et al.   EUKARYOTIC CELL

Homoserine Toxicity in Saccharomyces cerevisiae and Candida albicans Homoserine Kinase (thr1Δ) Mutants

(2010) Joanne M. Kingsbury et al.   EUKARYOTIC CELL

Evaluation of Lysine Biosynthesis as an Antifungal Drug Target: Biochemical Characterization of Aspergillus fumigatus Homocitrate Synthase and Virulence Studies

(2010) Felicitas Schöbel et al.   EUKARYOTIC CELL

Candida glabratatryptophan-based pigment production via the Ehrlich pathway

(2010) Sascha Brunke et al.   MOLECULAR MICROBIOLOGY

Disruption of Homocitrate Synthase Genes in Candida albicans Affects Growth But Not Virulence

(2010) Krzysztof Kur et al.   MYCOPATHOLOGIA

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

(2010) J. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic analysis of site-directed mutants of methionine synthase from Candida albicans

(2009) Priya Prasannan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis, antifungal activities and 3D-QSAR study of N-(5-substituted-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamides

(2009) Xing-Hai Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2 ) mutants is influenced by the carbon source and rapamycin

(2009) J. M. Kingsbury et al.   MICROBIOLOGY-SGM

Discovery of Pathogenicity Genes in the Crucifer Anthracnose FungusColletotrichum higginsianum, Using Random Insertional Mutagenesis

(2009) Aurélie Huser et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Threonine biosynthetic genes are essential in Cryptococcus neoformans

(2008) J. M. Kingsbury et al.   MICROBIOLOGY-SGM

Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast

(2008) M. Gustavsson et al.   RNA

Thiahomoisocitrate: A highly potent inhibitor of homoisocitrate dehydrogenase involved in the α-aminoadipate pathway

(2007) Takashi Yamamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Delineation of an in vivo inhibitor for Aspergillus glutamate dehydrogenase

(2007) Rajarshi Choudhury et al.   ENZYME AND MICROBIAL TECHNOLOGY