Arginine deprivation affects glioblastoma cell adhesion, invasiveness and actin cytoskeleton organization by impairment of β-actin arginylation

Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging

(2013) M. D. Allen et al.   CANCER RESEARCH

PHLP2 is essential and plays a role in ciliogenesis and microtubule assembly inTetrahymena thermophila

(2013) Cezary Bregier et al.   JOURNAL OF CELLULAR PHYSIOLOGY

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

(2013) Martje Tönjes et al.   NATURE MEDICINE

Molecular Identification of Carnosine N-Methyltransferase as Chicken Histamine N-Methyltransferase-Like Protein (HNMT-Like)

(2013) Jakub Drozak et al.   PLoS One

Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma

(2013) N Syed et al.   Cell Death & Disease

Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis

(2012) Sougata Saha et al.   BIOCHEMICAL PHARMACOLOGY

Post-translational modification and regulation of actin

(2012) Jonathan R Terman et al.   CURRENT OPINION IN CELL BIOLOGY

A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma

(2012) Thomas Yau et al.   INVESTIGATIONAL NEW DRUGS

Arginylation-dependent regulation of a proteolytic product of talin is essential for cell–cell adhesion

(2012) Fangliang Zhang et al.   JOURNAL OF CELL BIOLOGY

Arginylation regulates myofibrils to maintain heart function and prevent dilated cardiomyopathy

(2012) Satoshi Kurosaka et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Rapid re-expression of CD133 protein in colorectal cancer cell lines in vitro and in vivo

(2012) Susann Peickert et al.   LABORATORY INVESTIGATION

Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia

(2012) K Morrow et al.   LEUKEMIA

Targeting methionine auxotrophy in cancer: discovery & exploration

(2011) Vaidehi Agrawal et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Single amino acid arginine starvation efficiently sensitizes cancer cells to canavanine treatment and irradiation

(2011) Bozhena Vynnytska-Myronovska et al.   INTERNATIONAL JOURNAL OF CANCER

Myosin VI in PC12 cells plays important roles in cell migration and proliferation but not in catecholamine secretion

(2011) Łukasz Majewski et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase

(2011) Daniele Covini et al.   Recent Patents on Anti-Cancer Drug Discovery

A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients

(2010) T-S Yang et al.   BRITISH JOURNAL OF CANCER

Cancer cell sensitivity to arginine deprivationin vitrois not determined by endogenous levels of arginine metabolic enzymes

(2010) Yaroslav P Bobak et al.   CELL BIOLOGY INTERNATIONAL

Phase II Study of Pegylated Arginine Deiminase for Nonresectable and Metastatic Hepatocellular Carcinoma

(2010) Evan S. Glazer et al.   JOURNAL OF CLINICAL ONCOLOGY

Comparative evaluation of preclinical in vivo models for the assessment of replicating retroviral vectors for the treatment of glioblastoma

(2010) Juraj Hlavaty et al.   JOURNAL OF NEURO-ONCOLOGY

Arginylation Regulates Intracellular Actin Polymer Level by Modulating Actin Properties and Binding of Capping and Severing Proteins

(2010) Sougata Saha et al.   MOLECULAR BIOLOGY OF THE CELL

Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis

(2009) R. H. Kim et al.   CANCER RESEARCH

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Arginine Deprivation as a Targeted Therapy for Cancer

(2008) L. Feun et al.   CURRENT PHARMACEUTICAL DESIGN

Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase

(2008) Tawnya L. Bowles et al.   INTERNATIONAL JOURNAL OF CANCER

Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages

(2008) B.-S. Choi et al.   JOURNAL OF LEUKOCYTE BIOLOGY