Article
Plant Sciences
Abujunaid Khan, Madhukar S. Said, Balasaheb R. Borade, Rajesh Gonnade, Vitthal Barvkar, Ravindar Kontham, Syed G. Dastager
Summary: Three novel compounds and a new acid were identified from the strain Amycolatopsis sp. MCC 0218, and their chemical structures and activities against methicillin-susceptible and -resistant Staphylococcus aureus were determined.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Guangrong Liu, Mayila Kamilijiang, Aytursun Abuduwaili, Deng Zang, Nuermaimaiti Abudukelimu, Geyu Liu, Abulimiti Yili, Haji Akber AIsa
Summary: The optimum conditions for extracting Saussurea involucrata polysaccharide (SIP) were determined, and a new acidic polysaccharide SIP-II was isolated and characterized. SIP-II showed significant anti-inflammatory activity in LPS-stimulated macrophages, potentially making it a valuable ingredient in the functional food and pharmaceutical industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Tong Sun, Dong Hu, Zhizhang Guo, Hanwen Gong, Qiangwei Xin, Yandong Mu, Jie Weng, Jianshu Li, Xingyu Chen
Summary: Successfully treating bone infections is challenging due to the lack of targeted drug delivery. In this study, a modified beta-cyclodextrin (Asp6-beta-CD) was used to specifically target bone tissue and loaded with norfloxacin (NFX) to enhance its antibacterial activity. The results showed that Asp6-beta-CD@NFX efficiently targeted bone tissue, reduced inflammation, and promoted bone tissue repair.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Materials Science, Multidisciplinary
Alvin Lim Teik Zheng, Hisham N. Farrag, Sarah Sabidi, Tamaki Kato, Toshinari Maeda, Yoshito Andou
Summary: The study found that cyclic peptides immobilized on reduced graphene oxide exhibited selective antibacterial effects, with tyrosine and histidine-based peptides showing higher antibacterial activity. The enhanced antibacterial potency can be attributed to the synergistic effect between the antimicrobial peptides and graphene oxide.
Article
Energy & Fuels
Xi Wu, Chunshan Zheng, He Li, Jiexin Lu, Yi Lu, Shiliang Shi, Yuannan Zheng, Zheng Wang
Summary: This study analyzed the pore structure and surface morphology of coal samples treated with microwave-liquid nitrogen cyclic processing (MLCP). The results showed that MLCP can increase coal reservoir permeability, and the frequency of cycles has a significant impact on pore volume.
Article
Chemistry, Physical
Summaira Fayyaz, Farzana Shaheen, Saqib Ali, Samar Naseer, Scopelliti Rosario
Summary: The synthesis of five new antimicrobial organotin(IV) carbodithioates with different coordination geometries in solid and solution states showed significant activity against five different bacterial strains.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Review
Biophysics
Tahereh Seifi, Ali Reza Kamali
Summary: Graphene and its derivatives show promising anti-pathogenic properties, including antibacterial, antiviral, antifungal, and biofilm-forming performance. The factors influencing the antibacterial activity of graphene nanomaterials and the mechanisms involved are still controversial.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Jia-Xuan Yan, Qihao Wu, Mitasree Maity, Doug R. Braun, Imraan Alas, Xiao Wang, Xing Yin, Yanlong Zhu, Bailey A. Bell, Scott R. Rajski, Ying Ge, Douglas D. Richardson, Wendy Zhong, Tim S. Bugni
Summary: Cyclic peptides are a promising source of drug leads, but their structural complexity poses challenges for structure elucidation. Isotopic fine structure analysis, NMR, and mass spectrometry techniques were used to determine the sequence and stereochemistry of streptnatamide A, a cyclic peptide from a marine-derived Streptomyces sp. The analysis also tentatively identified and annotated a biosynthetic gene cluster for streptnatamide A based on genomic sequencing data. These analytical tools are valuable for overcoming the challenges of cyclic peptide structure elucidation and accelerating the development of bioactive cyclic peptides.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Tayebe Zandvakili, S. Jamil Fatemi, S. Yousef Ebrahimipour, Hadi Ebrahimnejad, Michal Dusek, Vaclav Eigner
Summary: The synthesized V(V) complex showed moderate and selective antibacterial activity against various strains, along with potential anti-biofilm properties and free-radical scavenging ability.
Article
Biochemical Research Methods
Charanjeet Singh, Sandeep Sharma, Sundeep Jaglan, Juan C. Aphesteguy, Silvia Jacobo, I. A. Abdel-Latif, Hasan B. Albargi, Ravinder Kaur, Jasbir Singh, Sarika Sharma
Summary: In this study, an alternative electrical method to determine the anti-bacterial activity of compounds was proposed. Polyaniline/magnetite (Fe3O4/PANI) and polyaniline/hydrochloric acid (HCl/PANI) nanocomposites were prepared and their anti-bacterial activity was tested. The electrical characteristics of the prepared composites were measured and found to be in agreement with the observed bacterial inhibition. By tuning the electrical parameters, bacterial growth in various compounds can be controlled effectively.
IEEE TRANSACTIONS ON NANOBIOSCIENCE
(2023)
Article
Chemistry, Physical
Arbia Ben Khelifa, Khaireddine Ezzayani, Mouhieddinne Guergueb, Frederique Loiseau, Eric Saint-Aman, Habib Nasri
Summary: A new magnesium(II) polymer compound has been synthesized and characterized, showing specific crystal structure, photophysical properties, spectroscopic characteristics, and potential antibacterial activity.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Engineering, Biomedical
Mariana Barbosa, Helvio Simoes, Sandra N. Pinto, Ana S. Macedo, Pedro Fonte, D. Miguel F. Prazeres
Summary: The study proposes a new strategy to modify cellulose-based materials with an antimicrobial peptide MP196 through a biomolecular recognition approach. The modified materials displayed significantly higher antibacterial activity against E. coli, P. aeruginosa, and S. aureus compared to materials prepared by physical adsorption of MP196. The biomolecular strategy provides a versatile concept for the functionalization of cellulose materials for various applications including drug delivery systems and tissue engineering.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Applied
Xianli Zhang, Xiaojie Yue, Bin Ma, Xing Fu, Heling Ren, Meihu Ma
Summary: The study evaluates the effect of ultrasonic pretreatment combined with glycation on the structural characteristics and antibacterial activity of ovotransferrin, showing that this technique is effective in improving the biological activity of OVT.
Article
Biochemistry & Molecular Biology
Adriana Corina Hangan, Roxana Liana Lucaciu, Alexandru Turza, Lucia Dican, Bogdan Sevastre, Emoeke Pall, Luminita Simona Oprean, Gheorghe Borodi
Summary: The discovery of new non-toxic metal complexes with biological activity is an active area of research. Two Cu+2 complexes with new ligands were synthesized and characterized by X-ray crystallography. Both complexes showed in vitro biological activities, with complex C2 being more active. The complexes exhibited distorted square pyramidal square-planar geometries and were characterized by FT-IR and UV-Vis spectroscopy. The antibacterial activity of the complexes against four Gram-positive and two Gram-negative bacteria was determined using the microdilution method, and cytotoxicity studies were carried out on tumor cell lines and a normal cell line. Flow cytometric assessment of apoptosis induced by the complexes was also performed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Yan Jiang, Zhipeng Shang, Xinyue Lv, Min Du, Li Ma, Guige Hou, Jing Chen, Chunhua Wang, Feng Zhao
Summary: A polysaccharide (HPP-1S) extracted from sea urchin gonads showed potential as a low toxic antitumor agent. It induced apoptosis in Hela cells and exhibited significant antitumor efficacy in nude mice.
CARBOHYDRATE POLYMERS
(2022)
